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    PHB1 prohibitin 1 [ Bos taurus (domestic cattle) ]

    Gene ID: 530409, updated on 27-Dec-2024

    Summary

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    Official Symbol
    PHB1provided by VGNC
    Official Full Name
    prohibitin 1provided by VGNC
    Primary source
    VGNC:VGNC:32808
    See related
    BGD:BT28516; Ensembl:ENSBTAG00000017120
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Bos taurus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Artiodactyla; Ruminantia; Pecora; Bovidae; Bovinae; Bos
    Also known as
    PHB
    Orthologs
    human mouse all
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    Genomic context

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    See PHB1 in Genome Data Viewer
    Location:
    chromosome: 19
    Exon count:
    8
    Annotation release Status Assembly Chr Location
    RS_2024_12 current ARS-UCD2.0 (GCF_002263795.3) 19 NC_037346.1 (37195939..37206559)

    Chromosome 19 - NC_037346.1Genomic Context describing neighboring genes Neighboring gene uncharacterized LOC132343059 Neighboring gene nerve growth factor receptor Neighboring gene zinc finger protein 652 Neighboring gene uncharacterized LOC112442651

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_037346.1 Chromosome 19 Reference ARS-UCD2.0 Primary Assembly

    Go to nucleotide: Graphics FASTA GenBank

    Expression

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    • Project title: Dominette sequence data
    • BioProject: PRJNA294306
    • Analysis date: Tue Dec 17 08:57:05 2024

    Bibliography

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    Related articles in PubMed

    1. Prohibitin as an oxidative stress biomarker in the eye. Lee H, et al. Int J Biol Macromol, 2010 Dec 1. PMID 20832420, Free PMC Article
    2. A whole-genome assembly of the domestic cow, Bos taurus. Zimin AV, et al. Genome Biol, 2009. PMID 19393038, Free PMC Article
    3. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. Strausberg RL, et al. Proc Natl Acad Sci U S A, 2002 Dec 24. PMID 12477932, Free PMC Article
    4. Manual GO annotation of predictive protein signatures: the InterPro approach to GO curation. Burge S, et al. Database (Oxford), 2012. PMID 22301074, Free PMC Article
    5. TreeGrafter: phylogenetic tree-based annotation of proteins with Gene Ontology terms and other annotations. Tang H, et al. Bioinformatics, 2019 Feb 1. PMID 30032202, Free PMC Article

    GeneRIFs: Gene References Into Functions

    Pathways from PubChem

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    General gene information

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    Markers

    Homology

    Clone Names

    • MGC127238

    Gene Ontology Provided by RefSeq

    Process Evidence Code Pubs
    involved_in mitochondrion organization IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in membrane IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    located_in mitochondrion IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    prohibitin 1
    Names
    prohibitin

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001034572.2 → NP_001029744.1  prohibitin 1

      See identical proteins and their annotated locations for NP_001029744.1

      Status: PROVISIONAL

      Source sequence(s)
      BC102094
      UniProtKB/Swiss-Prot
      Q3T165
      UniProtKB/TrEMBL
      A0AAA9TIW2
      Related
      ENSBTAP00000022759.3, ENSBTAT00000022759.5
      Conserved Domains (1) summary
      cd03401
      Location:27 → 221
      SPFH_prohibitin; Prohibitin family; SPFH (stomatin, prohibitin, flotillin, and HflK/C) superfamily

    RefSeqs of Annotated Genomes: GCF_002263795.3-RS_2024_12

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference ARS-UCD2.0 Primary Assembly

    Genomic

    1. NC_037346.1 Reference ARS-UCD2.0 Primary Assembly

      Range
      37195939..37206559
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_059878106.1 → XP_059734089.1  prohibitin 1 isoform X1

      UniProtKB/Swiss-Prot
      Q3T165
      UniProtKB/TrEMBL
      A0AAA9TIW2

    2. XM_059878105.1 → XP_059734088.1  prohibitin 1 isoform X1

      UniProtKB/Swiss-Prot
      Q3T165
      UniProtKB/TrEMBL
      A0AAA9TIW2

    3. XM_005220569.4 → XP_005220626.1  prohibitin 1 isoform X1

      See identical proteins and their annotated locations for XP_005220626.1

      UniProtKB/Swiss-Prot
      Q3T165
      UniProtKB/TrEMBL
      A0AAA9TIW2
      Conserved Domains (1) summary
      cd03401
      Location:27 → 221
      SPFH_prohibitin; Prohibitin family; SPFH (stomatin, prohibitin, flotillin, and HflK/C) superfamily
    Nucleotide Protein Strain
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q3T165.1 GenPept UniProtKB/Swiss-Prot:Q3T165

    Gene LinkOut

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