U.S. flag

An official website of the United States government

Format

Send to:

Choose Destination

Links from GEO Profiles

    • Showing Current items.

    TRIB2 tribbles pseudokinase 2 [ Bos taurus (domestic cattle) ]

    Gene ID: 352960, updated on 30-Jan-2025

    Summary

    Go to the top of the page Help
    Official Symbol
    TRIB2provided by VGNC
    Official Full Name
    tribbles pseudokinase 2provided by VGNC
    Primary source
    VGNC:VGNC:36309
    See related
    BGD:BT12305; EnsemblRapid:ENSBTAG00070006060
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Bos taurus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Artiodactyla; Ruminantia; Pecora; Bovidae; Bovinae; Bos
    Also known as
    TRB2; TRB-2
    Orthologs
    human mouse all
    NEW
    Try the new Gene table
    Try the new Transcript table

    Genomic context

    Go to the top of the page Help
    See TRIB2 in Genome Data Viewer
    Location:
    chromosome: 11
    Exon count:
    5
    Annotation release Status Assembly Chr Location
    RS_2024_12 current ARS-UCD2.0 (GCF_002263795.3) 11 NC_037338.1 (85237101..85266633, complement)

    Chromosome 11 - NC_037338.1Genomic Context describing neighboring genes Neighboring gene uncharacterized LOC112448944 Neighboring gene uncharacterized LOC104973452 Neighboring gene uncharacterized LOC101904537 Neighboring gene uncharacterized LOC132346620 Neighboring gene transfer RNA histidin (anticodon GUG)

    Genomic regions, transcripts, and products

    Go to the top of the page Help
    Genomic Sequence:
    NC_037338.1 Chromosome 11 Reference ARS-UCD2.0 Primary Assembly

    Go to nucleotide: Graphics FASTA GenBank

    Expression

    Go to the top of the page Help
    • Project title: Dominette sequence data
    • BioProject: PRJNA294306
    • Analysis date: Tue Dec 17 08:57:05 2024

    Bibliography

    Go to the top of the pageHelp

    Related articles in PubMed

    1. Identification of downregulated messenger RNAs in bovine granulosa cells of dominant follicles following stimulation with human chorionic gonadotropin. Ndiaye K, et al. Biol Reprod, 2005 Aug. PMID 15829623
    2. A whole-genome assembly of the domestic cow, Bos taurus. Zimin AV, et al. Genome Biol, 2009. PMID 19393038, Free PMC Article
    3. Manual GO annotation of predictive protein signatures: the InterPro approach to GO curation. Burge S, et al. Database (Oxford), 2012. PMID 22301074, Free PMC Article
    4. TreeGrafter: phylogenetic tree-based annotation of proteins with Gene Ontology terms and other annotations. Tang H, et al. Bioinformatics, 2019 Feb 1. PMID 30032202, Free PMC Article

    GeneRIFs: Gene References Into Functions

    General gene information

    Go to the top of the page Help

    Markers

    Homology

    Gene Ontology Provided by RefSeq

    Function Evidence Code Pubs
    enables ATP binding IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    enables mitogen-activated protein kinase kinase binding IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    enables protein kinase activity IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in positive regulation of proteasomal ubiquitin-dependent protein catabolic process IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in protein phosphorylation IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in regulation of MAP kinase activity IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in nucleus IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 

    General protein information

    Go to the top of the page Help
    Preferred Names
    tribbles homolog 2
    Names
    tribbles-like protein 2

    NCBI Reference Sequences (RefSeq)

    Go to the top of the page Help

    NEW Try the new Transcript table

    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_178317.3 → NP_847887.2  tribbles homolog 2

      See identical proteins and their annotated locations for NP_847887.2

      Status: PROVISIONAL

      Source sequence(s)
      AY360147
      UniProtKB/Swiss-Prot
      A4FV13, Q5GLH2, Q864R4
      Related
      ENSBTAP00070008113.1, ENSBTAT00070013892.1
      Conserved Domains (1) summary
      cd14022
      Location:67 → 308
      PK_TRB2; Pseudokinase domain of Tribbles Homolog 2

    RefSeqs of Annotated Genomes: GCF_002263795.3-RS_2024_12

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference ARS-UCD2.0 Primary Assembly

    Genomic

    1. NC_037338.1 Reference ARS-UCD2.0 Primary Assembly

      Range
      85237101..85266633 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_024998358.2 → XP_024854126.1  tribbles homolog 2 isoform X1

      Conserved Domains (1) summary
      cd14022
      Location:67 → 324
      PK_TRB2; Pseudokinase domain of Tribbles Homolog 2

    2. XM_024998359.2 → XP_024854127.1  tribbles homolog 2 isoform X2

      UniProtKB/Swiss-Prot
      A4FV13, Q5GLH2, Q864R4
      Conserved Domains (1) summary
      cd14022
      Location:67 → 308
      PK_TRB2; Pseudokinase domain of Tribbles Homolog 2

    3. XM_024998357.2 → XP_024854125.1  tribbles homolog 2 isoform X1

      Conserved Domains (1) summary
      cd14022
      Location:67 → 324
      PK_TRB2; Pseudokinase domain of Tribbles Homolog 2
    Nucleotide Protein Strain
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q5GLH2.1 GenPept UniProtKB/Swiss-Prot:Q5GLH2

    Gene LinkOut

    The following LinkOut resources are supplied by external providers. These providers are responsible for maintaining the links.

    Molecular Biology Databases
    Research Materials