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    HSD17B6 hydroxysteroid (17-beta) dehydrogenase 6 [ Bos taurus (domestic cattle) ]

    Gene ID: 533086, updated on 30-Jan-2025

    Summary

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    Gene symbol
    HSD17B6
    Gene description
    hydroxysteroid (17-beta) dehydrogenase 6
    See related
    BGD:BT18152; EnsemblRapid:ENSBTAG00070011731
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Bos taurus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Artiodactyla; Ruminantia; Pecora; Bovidae; Bovinae; Bos
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    Genomic context

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    See HSD17B6 in Genome Data Viewer
    Location:
    chromosome: 5
    Exon count:
    5
    Annotation release Status Assembly Chr Location
    RS_2024_12 current ARS-UCD2.0 (GCF_002263795.3) 5 NC_037332.1 (56674165..56696104, complement)

    Chromosome 5 - NC_037332.1Genomic Context describing neighboring genes Neighboring gene small nucleolar RNA U2-19 Neighboring gene small nucleolar RNA U2-30 Neighboring gene transfer RNA glycine (anticodon CCC) Neighboring gene transfer RNA phenylalanine (anticodon GAA) Neighboring gene DNA primase subunit 1 Neighboring gene uncharacterized LOC132345299

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_037332.1 Chromosome 5 Reference ARS-UCD2.0 Primary Assembly

    Go to nucleotide: Graphics FASTA GenBank

    Expression

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    • Project title: Dominette sequence data
    • BioProject: PRJNA294306
    • Analysis date: Tue Dec 17 08:57:05 2024

    Bibliography

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    Related articles in PubMed

    1. A whole-genome assembly of the domestic cow, Bos taurus. Zimin AV, et al. Genome Biol, 2009. PMID 19393038, Free PMC Article
    2. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. Strausberg RL, et al. Proc Natl Acad Sci U S A, 2002 Dec 24. PMID 12477932, Free PMC Article
    3. TreeGrafter: phylogenetic tree-based annotation of proteins with Gene Ontology terms and other annotations. Tang H, et al. Bioinformatics, 2019 Feb 1. PMID 30032202, Free PMC Article

    GeneRIFs: Gene References Into Functions

    Pathways from PubChem

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    General gene information

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    Homology

    Clone Names

    • MGC127926

    Gene Ontology Provided by RefSeq

    Function Evidence Code Pubs
    enables all-trans-retinol dehydrogenase (NAD+) activity IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in retinol metabolic process IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in steroid metabolic process IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in intracellular membrane-bounded organelle IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    17-beta-hydroxysteroid dehydrogenase type 6
    Names
    17-beta-HSD 6
    17-beta-HSD6
    3-alpha->beta-HSE
    3-alpha->beta-hydroxysteroid epimerase
    hydroxysteroid (17-beta) dehydrogenase 6 homolog
    oxidative 3-alpha hydroxysteroid dehydrogenase
    NP_001030472.1

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001035395.2 → NP_001030472.1  17-beta-hydroxysteroid dehydrogenase type 6 precursor

      See identical proteins and their annotated locations for NP_001030472.1

      Status: PROVISIONAL

      Source sequence(s)
      BC102626
      UniProtKB/Swiss-Prot
      Q3T001
      UniProtKB/TrEMBL
      F1MG20
      Related
      ENSBTAP00070015746.1, ENSBTAT00070026424.1
      Conserved Domains (2) summary
      cd09805
      Location:30 → 306
      type2_17beta_HSD-like_SDR_c; human 17beta-hydroxysteroid dehydrogenase type 2 (type 2 17beta-HSD)-like, classical (c) SDRs
      pfam00106
      Location:30 → 214
      adh_short; short chain dehydrogenase

    RefSeqs of Annotated Genomes: GCF_002263795.3-RS_2024_12

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference ARS-UCD2.0 Primary Assembly

    Genomic

    1. NC_037332.1 Reference ARS-UCD2.0 Primary Assembly

      Range
      56674165..56696104 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)
    Nucleotide Protein Strain
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q3T001.1 GenPept UniProtKB/Swiss-Prot:Q3T001

    Gene LinkOut

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