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    FRMD4A FERM domain containing 4A [ Bos taurus (domestic cattle) ]

    Gene ID: 510714, updated on 27-Dec-2024

    Summary

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    Official Symbol
    FRMD4Aprovided by VGNC
    Official Full Name
    FERM domain containing 4Aprovided by VGNC
    Primary source
    VGNC:VGNC:29114
    See related
    BGD:BT21478; Ensembl:ENSBTAG00000008279
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Bos taurus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Artiodactyla; Ruminantia; Pecora; Bovidae; Bovinae; Bos
    Orthologs
    human mouse all
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    Genomic context

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    See FRMD4A in Genome Data Viewer
    Location:
    chromosome: 13
    Exon count:
    35
    Annotation release Status Assembly Chr Location
    RS_2024_12 current ARS-UCD2.0 (GCF_002263795.3) 13 NC_037340.1 (28349307..29199106, complement)

    Chromosome 13 - NC_037340.1Genomic Context describing neighboring genes Neighboring gene transfer RNA aspartic acid (anticodon AUC) Neighboring gene uncharacterized LOC132346889 Neighboring gene pre-mRNA processing factor 18 Neighboring gene uncharacterized LOC104973746 Neighboring gene microRNA mir-2304 Neighboring gene transfer RNA glutamic acid (anticodon CUC) Neighboring gene craniofacial development protein 2-like Neighboring gene uncharacterized LOC132346888 Neighboring gene family with sequence similarity 107 member B Neighboring gene cerebral dopamine neurotrophic factor

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_037340.1 Chromosome 13 Reference ARS-UCD2.0 Primary Assembly

    Go to nucleotide: Graphics FASTA GenBank

    Expression

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    • Project title: Dominette sequence data
    • BioProject: PRJNA294306
    • Analysis date: Tue Dec 17 08:57:05 2024

    Bibliography

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    Related articles in PubMed

    1. A whole-genome assembly of the domestic cow, Bos taurus. Zimin AV, et al. Genome Biol, 2009. PMID 19393038, Free PMC Article
    2. Manual GO annotation of predictive protein signatures: the InterPro approach to GO curation. Burge S, et al. Database (Oxford), 2012. PMID 22301074, Free PMC Article
    3. TreeGrafter: phylogenetic tree-based annotation of proteins with Gene Ontology terms and other annotations. Tang H, et al. Bioinformatics, 2019 Feb 1. PMID 30032202, Free PMC Article

    GeneRIFs: Gene References Into Functions

    General gene information

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    Markers

    Homology

    Gene Ontology Provided by RefSeq

    Process Evidence Code Pubs
    involved_in establishment of epithelial cell polarity IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in adherens junction IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    located_in bicellular tight junction IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    located_in cytoskeleton IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    FERM domain-containing protein 4A

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001192267.1 → NP_001179196.1  FERM domain-containing protein 4A

      See identical proteins and their annotated locations for NP_001179196.1

      Status: PROVISIONAL

      Source sequence(s)
      NKLS02000013
      UniProtKB/TrEMBL
      A0AAA9TI08, E1BHJ3
      Related
      ENSBTAP00000010894.5, ENSBTAT00000010894.7
      Conserved Domains (5) summary
      smart00295
      Location:59 → 259
      B41; Band 4.1 homologues
      cd13191
      Location:255 → 365
      FERM_C_FRMD4A_FRMD4B; FERM domain C-lobe of FERM domain-containing protein 4A and 4B (FRMD4A and 4B)
      pfam00373
      Location:145 → 259
      FERM_M; FERM central domain
      pfam09379
      Location:62 → 123
      FERM_N; FERM N-terminal domain
      pfam11819
      Location:422 → 529
      DUF3338; Domain of unknown function (DUF3338)

    RefSeqs of Annotated Genomes: GCF_002263795.3-RS_2024_12

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference ARS-UCD2.0 Primary Assembly

    Genomic

    1. NC_037340.1 Reference ARS-UCD2.0 Primary Assembly

      Range
      28349307..29199106 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_059892529.1 → XP_059748512.1  FERM domain-containing protein 4A isoform X5

      UniProtKB/TrEMBL
      A0AAA9TFH0, A0AAA9TI08

    2. XM_059892528.1 → XP_059748511.1  FERM domain-containing protein 4A isoform X5

      UniProtKB/TrEMBL
      A0AAA9TFH0, A0AAA9TI08

    3. XM_059892530.1 → XP_059748513.1  FERM domain-containing protein 4A isoform X5

      UniProtKB/TrEMBL
      A0AAA9TFH0, A0AAA9TI08
      Related
      ENSBTAP00000095751.1, ENSBTAT00000118089.1

    4. XM_059892526.1 → XP_059748509.1  FERM domain-containing protein 4A isoform X3

      UniProtKB/TrEMBL
      A0AAA9TI08

    5. XM_059892525.1 → XP_059748508.1  FERM domain-containing protein 4A isoform X2

      UniProtKB/TrEMBL
      A0AAA9SAF7, A0AAA9TI08
      Related
      ENSBTAP00000082320.1, ENSBTAT00000103937.1

    6. XM_059892531.1 → XP_059748514.1  FERM domain-containing protein 4A isoform X6

      UniProtKB/TrEMBL
      A0AAA9TI08

    7. XM_059892532.1 → XP_059748515.1  FERM domain-containing protein 4A isoform X6

      UniProtKB/TrEMBL
      A0AAA9TI08

    8. XM_059892527.1 → XP_059748510.1  FERM domain-containing protein 4A isoform X4

      UniProtKB/TrEMBL
      A0AAA9SKL5

    9. XM_059892524.1 → XP_059748507.1  FERM domain-containing protein 4A isoform X1

      UniProtKB/TrEMBL
      A0AAA9SKL5
      Related
      ENSBTAP00000084421.1, ENSBTAT00000099633.1
    Nucleotide Protein Strain
    Heading Accession and Version

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