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    LINC02086 long intergenic non-protein coding RNA 2086 [ Homo sapiens (human) ]

    Gene ID: 105371809, updated on 10-Dec-2024

    Summary

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    Official Symbol
    LINC02086provided by HGNC
    Official Full Name
    long intergenic non-protein coding RNA 2086provided by HGNC
    Primary source
    HGNC:HGNC:52936
    See related
    AllianceGenome:HGNC:52936
    Gene type
    ncRNA
    RefSeq status
    VALIDATED
    Organism
    Homo sapiens
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
    Expression
    Biased expression in colon (RPKM 2.5), appendix (RPKM 0.5) and 4 other tissues See more
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    Genomic context

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    See LINC02086 in Genome Data Viewer
    Location:
    17q21.32
    Exon count:
    12
    Annotation release Status Assembly Chr Location
    RS_2024_08 current GRCh38.p14 (GCF_000001405.40) 17 NC_000017.11 (48642627..48707346)
    RS_2024_08 current T2T-CHM13v2.0 (GCF_009914755.1) 17 NC_060941.1 (49506223..49570947)
    RS_2024_09 previous assembly GRCh37.p13 (GCF_000001405.25) 17 NC_000017.10 (46719989..46784708)

    Chromosome 17 - NC_000017.11Genomic Context describing neighboring genes Neighboring gene H3K27ac-H3K4me1 hESC enhancer GRCh37_chr17:46702573-46703250 Neighboring gene ReSE screen-validated silencer GRCh37_chr17:46704661-46704816 Neighboring gene homeobox B9 Neighboring gene HOXB cluster antisense RNA 4 Neighboring gene microRNA 196a-1 Neighboring gene long intergenic non-protein coding RNA 3057 Neighboring gene H3K27ac-H3K4me1 hESC enhancer GRCh37_chr17:46718588-46719586 Neighboring gene H3K27ac-H3K4me1 hESC enhancer GRCh37_chr17:46719587-46720583 Neighboring gene H3K27ac-H3K4me1 hESC enhancer GRCh37_chr17:46723751-46724419 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 12339 Neighboring gene ribosomal protein L9 pseudogene 28 Neighboring gene ReSE screen-validated silencer GRCh37_chr17:46790297-46790470 Neighboring gene cytochrome c oxidase subunit 6B1 pseudogene 2 Neighboring gene NANOG-H3K27ac-H3K4me1 hESC enhancer GRCh37_chr17:46799826-46800340 Neighboring gene PRAC2 small nuclear protein Neighboring gene PRAC1 small nuclear protein

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Expression

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    • Project title: HPA RNA-seq normal tissues
    • Description: RNA-seq was performed of tissue samples from 95 human individuals representing 27 different tissues in order to determine tissue-specificity of all protein-coding genes
    • BioProject: PRJEB4337
    • Publication: PMID 24309898
    • Analysis date: Wed Apr 4 07:08:55 2018

    Bibliography

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    Related articles in PubMed

    1. LINC02086 promotes cell viability and inhibits cell apoptosis in breast cancer by sponging miR-6757-5p and up-regulating EPHA2. Han X, et al. World J Surg Oncol, 2023 Nov 27. PMID 38008720, Free PMC Article

    GeneRIFs: Gene References Into Functions

    What's a GeneRIF?
    1. LINC02086 promotes cell viability and inhibits cell apoptosis in breast cancer by sponging miR-6757-5p and up-regulating EPHA2.
      Title: LINC02086 promotes cell viability and inhibits cell apoptosis in breast cancer by sponging miR-6757-5p and up-regulating EPHA2.
    Submit: New GeneRIF Correction

    Phenotypes

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    Review eQTL and phenotype association data in this region using PheGenI

    Variation

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    See variants in ClinVar

    See studies and variants in dbVar

    See Variation Viewer (GRCh37.p13)

    General gene information

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    Other Names

    • CTD-2377D24.6
    • CTD-2377D24.8

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    RNA

    1. NR_189644.1 RNA Sequence

      Status: VALIDATED

      Source sequence(s)
      AC091179, AC103702

    2. NR_189645.1 RNA Sequence

      Status: VALIDATED

      Source sequence(s)
      AC091179, AC103702

    3. NR_189646.1 RNA Sequence

      Status: VALIDATED

      Source sequence(s)
      AC091179, AC103702

    4. NR_189647.1 RNA Sequence

      Status: VALIDATED

      Source sequence(s)
      AC091179, AC103702

    5. NR_189648.1 RNA Sequence

      Status: VALIDATED

      Source sequence(s)
      AC091179, AC103702

    RefSeqs of Annotated Genomes: GCF_000001405.40-RS_2024_08

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCh38.p14 Primary Assembly

    Genomic

    1. NC_000017.11 Reference GRCh38.p14 Primary Assembly

      Range
      48642627..48707346
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    Alternate T2T-CHM13v2.0

    Genomic

    1. NC_060941.1 Alternate T2T-CHM13v2.0

      Range
      49506223..49570947
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)
    Nucleotide Protein
    Heading Accession and Version

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