ATG7 autophagy related 7 [Homo sapiens (human)] - Gene

Summary

Official Symbol: ATG7provided by HGNC
Official Full Name: autophagy related 7provided by HGNC
Primary source: HGNC:HGNC:16935
See related: Ensembl:ENSG00000197548 MIM:608760; AllianceGenome:HGNC:16935
Gene type: protein coding
RefSeq status: REVIEWED
Organism: Homo sapiens
Lineage: Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
Also known as: GSA7; APG7L; SCAR31; APG7-LIKE
Summary: This gene encodes an E1-like activating enzyme that is essential for autophagy and cytoplasmic to vacuole transport. The encoded protein is also thought to modulate p53-dependent cell cycle pathways during prolonged metabolic stress. It has been associated with multiple functions, including axon membrane trafficking, axonal homeostasis, mitophagy, adipose differentiation, and hematopoietic stem cell maintenance. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Sep 2015]
Expression: Ubiquitous expression in ovary (RPKM 10.0), thyroid (RPKM 8.3) and 25 other tissues See more
Orthologs: mouse all
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Genomic context

Location:: 3p25.3

Exon count:: 32

Annotation release	Status	Assembly	Chr	Location
RS_2024_08	current	GRCh38.p14 (GCF_000001405.40)	3	NC_000003.12 (11272397..11576353)
RS_2024_08	current	T2T-CHM13v2.0 (GCF_009914755.1)	3	NC_060927.1 (11267348..11571596)
RS_2024_09	previous assembly	GRCh37.p13 (GCF_000001405.25)	3	NC_000003.11 (11314083..11606126)

Chromosome 3 - NC_000003.12 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Go to reference sequence details

Genomic Sequence:

Go to nucleotide: Graphics FASTA GenBank

Expression

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See details

Project title: Tissue-specific circular RNA induction during human fetal development
Description: 35 human fetal samples from 6 tissues (3 - 7 replicates per tissue) collected between 10 and 20 weeks gestational time were sequenced using Illumina TruSeq Stranded Total RNA
BioProject: PRJNA270632
Publication: PMID 26076956
Analysis date: Mon Apr 2 22:54:59 2018

Bibliography

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GeneRIFs: Gene References Into Functions

What's a GeneRIF?

circCUL3 drives malignant progression of cervical cancer by activating autophagy through sponge miR-223-3p upregulation of ATG7.
Title: circCUL3 drives malignant progression of cervical cancer by activating autophagy through sponge miR-223-3p upregulation of ATG7.
ATG7(2) Interacts With Metabolic Proteins and Regulates Central Energy Metabolism.
Title: ATG7(2) Interacts With Metabolic Proteins and Regulates Central Energy Metabolism.
IGF1R stimulates autophagy, enhances viability, and promotes insulin secretion in pancreatic beta cells in gestational diabetes mellitus by upregulating ATG7.
Title: IGF1R stimulates autophagy, enhances viability, and promotes insulin secretion in pancreatic β cells in gestational diabetes mellitus by upregulating ATG7.
ISG15 Promotes Progression and Gemcitabine Resistance of Pancreatic Cancer Cells Through ATG7.
Title: ISG15 Promotes Progression and Gemcitabine Resistance of Pancreatic Cancer Cells Through ATG7.
ATG7-mediated autophagy protects human gingival myofibroblasts from irradiation-induced apoptosis.
Title: ATG7-mediated autophagy protects human gingival myofibroblasts from irradiation-induced apoptosis.
Ablation of endothelial Atg7 inhibits ischemia-induced angiogenesis by upregulating Stat1 that suppresses Hif1a expression.
Title: Ablation of endothelial Atg7 inhibits ischemia-induced angiogenesis by upregulating Stat1 that suppresses Hif1a expression.
Improved Analysis of Prostate Cancer: VIM3, ATG7 and P53 Form a Complex and Activate miRNA 371a-3p.
Title: Improved Analysis of Prostate Cancer: VIM3, ATG7 and P53 Form a Complex and Activate miRNA 371a-3p.
Cytoplasmic Expression of TP53INP2 Modulated by Demethylase FTO and Mutant NPM1 Promotes Autophagy in Leukemia Cells.
Title: Cytoplasmic Expression of TP53INP2 Modulated by Demethylase FTO and Mutant NPM1 Promotes Autophagy in Leukemia Cells.
Increased Hepatic ATG7 mRNA and ATG7 Protein Expression in Nonalcoholic Steatohepatitis Associated with Obesity.
Title: Increased Hepatic ATG7 mRNA and ATG7 Protein Expression in Nonalcoholic Steatohepatitis Associated with Obesity.
Rare ATG7 genetic variants predispose patients to severe fatty liver disease.
Title: Rare ATG7 genetic variants predispose patients to severe fatty liver disease.

Submit: New GeneRIF Correction See all GeneRIFs (102)

Phenotypes

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Find tests for this gene in the NIH Genetic Testing Registry (GTR)

Review eQTL and phenotype association data in this region using PheGenI

Associated conditions

Description	Tests
Spinocerebellar ataxia, autosomal recessive 31 MedGen: C5543627 OMIM: 619422 GeneReviews: Not available	Compare labs

EBI GWAS Catalog

Description
Common variants in left/right asymmetry genes and pathways are associated with relative hand skill. EBI GWAS Catalog EBI GWAS CatalogPubMed
Discovery and refinement of loci associated with lipid levels. EBI GWAS Catalog EBI GWAS CatalogPubMed

Variation

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See variants in ClinVar

See studies and variants in dbVar

See Variation Viewer (GRCh37.p13)

See Variation Viewer (GRCh38)

HIV-1 interactions

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Replication interactions

Interaction	Pubs
Knockdown of autophagy related 7 homolog (ATG7) by siRNA inhibits HIV-1 replication in HeLa-derived TZM-bl cells	PubMed

Protein interactions

Protein	Gene	Interaction	Pubs
Tat	tat	The siRNA-mediated reduction of ATG7 protein reverses Torin-1-induced HIV-1 Tat degradation, suggesting ATG7 is involved in the lysosomal-mediated Tat degradation	PubMed
capsid	gag	Knockdown of autophagy factor ATG7 results in diminished levels of p24 yields in both primary monocyte- and U937-derived macrophages	PubMed

Go to the HIV-1, Human Interaction Database

Interactions

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Products	Interactant	Other Gene	Complex	Source	Pubs	Description

General gene information

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Markers

D3S3319 (e-PCR)
- UniSTS:12

SHGC-76717 (e-PCR)
- UniSTS:33306

SHGC-35171 (e-PCR)
- UniSTS:53537

SHGC-76706 (e-PCR)
- UniSTS:19260

D3S3137 (e-PCR)
- UniSTS:58948

D3S1263 (e-PCR), detects polymorphism
- UniSTS:39520

D3S3828 (e-PCR)
- UniSTS:56171

D3S3123 (e-PCR)
- UniSTS:2164

RH98571 (e-PCR)
- UniSTS:87169

D3S3429 (e-PCR)
- UniSTS:42385

D3S4030 (e-PCR)
- UniSTS:46488

D3S3454 (e-PCR)
- UniSTS:57768

STS-H83694 (e-PCR)
- UniSTS:47287

RH15949 (e-PCR)
- UniSTS:455

SHGC-57938 (e-PCR)
- UniSTS:28104

RH25345 (e-PCR)
- UniSTS:90316

D3S1263 (e-PCR), detects polymorphism
- UniSTS:35554

D3S3242 (e-PCR)
- UniSTS:153581

Gene Ontology Provided by GOA

Function	Evidence Code	Pubs
enables Atg12 activating enzyme activity	IBA Inferred from Biological aspect of Ancestor more info
enables Atg12 activating enzyme activity	IDA Inferred from Direct Assay more info	PubMed
enables Atg12 activating enzyme activity	IMP Inferred from Mutant Phenotype more info	PubMed
enables Atg12 activating enzyme activity	ISS Inferred from Sequence or Structural Similarity more info	PubMed
enables Atg8 activating enzyme activity	IBA Inferred from Biological aspect of Ancestor more info
enables protein binding	IPI Inferred from Physical Interaction more info	PubMed
enables protein homodimerization activity	IDA Inferred from Direct Assay more info	PubMed

Process	Evidence Code	Pubs
involved_in autophagosome assembly	IBA Inferred from Biological aspect of Ancestor more info
involved_in autophagosome assembly	IMP Inferred from Mutant Phenotype more info	PubMed
involved_in autophagy	IGI Inferred from Genetic Interaction more info	PubMed
acts_upstream_of_or_within autophagy	IMP Inferred from Mutant Phenotype more info	PubMed
involved_in autophagy	IMP Inferred from Mutant Phenotype more info	PubMed
involved_in autophagy	ISS Inferred from Sequence or Structural Similarity more info
involved_in cellular response to hyperoxia	IDA Inferred from Direct Assay more info	PubMed
involved_in cellular response to nitrogen starvation	IBA Inferred from Biological aspect of Ancestor more info
involved_in cellular response to starvation	IDA Inferred from Direct Assay more info	PubMed
involved_in cellular response to stress	IDA Inferred from Direct Assay more info	PubMed
involved_in defense response to virus	IMP Inferred from Mutant Phenotype more info	PubMed
involved_in macroautophagy	IMP Inferred from Mutant Phenotype more info	PubMed
involved_in mitophagy	IBA Inferred from Biological aspect of Ancestor more info
involved_in mitophagy	IGI Inferred from Genetic Interaction more info	PubMed
involved_in piecemeal microautophagy of the nucleus	IBA Inferred from Biological aspect of Ancestor more info
involved_in positive regulation of apoptotic process	IMP Inferred from Mutant Phenotype more info	PubMed
involved_in positive regulation of protein catabolic process	IMP Inferred from Mutant Phenotype more info	PubMed
acts_upstream_of_or_within positive regulation of protein modification process	IDA Inferred from Direct Assay more info	PubMed
acts_upstream_of_or_within protein lipidation	IDA Inferred from Direct Assay more info	PubMed
involved_in protein modification by small protein conjugation	IBA Inferred from Biological aspect of Ancestor more info
involved_in protein transport	IEA Inferred from Electronic Annotation more info
involved_in regulation of circadian rhythm	ISS Inferred from Sequence or Structural Similarity more info
involved_in rhythmic process	IEA Inferred from Electronic Annotation more info

Component	Evidence Code	Pubs
located_in axoneme	ISS Inferred from Sequence or Structural Similarity more info
is_active_in cytoplasm	IBA Inferred from Biological aspect of Ancestor more info
located_in cytoplasm	IDA Inferred from Direct Assay more info	PubMed
located_in cytosol	TAS Traceable Author Statement more info
located_in extracellular region	TAS Traceable Author Statement more info
located_in ficolin-1-rich granule lumen	TAS Traceable Author Statement more info
is_active_in phagophore assembly site	IBA Inferred from Biological aspect of Ancestor more info
is_active_in phagophore assembly site	IDA Inferred from Direct Assay more info	PubMed
located_in secretory granule lumen	TAS Traceable Author Statement more info

General protein information

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Preferred Names: ubiquitin-like modifier-activating enzyme ATG7

Names: APG7 autophagy 7-like; ATG12-activating enzyme E1 ATG7; hAGP7; ubiquitin-activating enzyme E1-like protein

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

NM_001136031.3 → NP_001129503.2 ubiquitin-like modifier-activating enzyme ATG7 isoform b

See identical proteins and their annotated locations for NP_001129503.2

Status: REVIEWED

Description

Transcript Variant: This variant (2) encodes isoform b.

Source sequence(s)

AC022001, AL122075, BC000091, DA177126

Consensus CDS

CCDS46752.1

UniProtKB/TrEMBL

B2RB57, B3KQM6

Related

ENSP00000347042.5, ENST00000354956.9

Conserved Domains (1) summary

cl25654
Location:15 → 675

ATG7_N; Ubiquitin-like modifier-activating enzyme ATG7 N-terminus
NM_001144912.2 → NP_001138384.1 ubiquitin-like modifier-activating enzyme ATG7 isoform c

Status: REVIEWED

Description

Transcript Variant: This variant (3) encodes isoform c.

Source sequence(s)

AC022001, AK303694, AL122075, BC000091, DA177126

Consensus CDS

CCDS46753.1

UniProtKB/TrEMBL

B2RB57, B3KQM6

Related

ENSP00000412580.2, ENST00000446450.6

Conserved Domains (3) summary

cd01486
Location:318 → 616

Apg7; Apg7 is an E1-like protein, that activates two different ubiquitin-like proteins, Apg12 and Apg8, and assigns them to specific E2 enzymes, Apg10 and Apg3, respectively. This leads to the covalent conjugation of Apg8 with phosphatidylethanolamine, an ...

TIGR01381
Location:15 → 614

E1_like_apg7; E1-like protein-activating enzyme Gsa7p/Apg7p

pfam16420
Location:13 → 282

ATG7_N; Ubiquitin-like modifier-activating enzyme ATG7 N-terminus
NM_001349232.2 → NP_001336161.1 ubiquitin-like modifier-activating enzyme ATG7 isoform a

Status: REVIEWED

Description

Transcript Variant: This variant (4) represents the longest transcript and encodes the longest isoform (a). Variants 1, 4, 5, 6, and 7 all encode the same isoform (a).

Source sequence(s)

AC020750, AC022001, AC026185, AC083855

Consensus CDS

CCDS2605.1

UniProtKB/Swiss-Prot

B4E170, E9PB95, O95352, Q7L8L0, Q9BWP2, Q9UFH4

UniProtKB/TrEMBL

B2RB57, B3KQM6

Related

ENSP00000510336.1, ENST00000693202.1

Conserved Domains (1) summary

cl25654
Location:15 → 702

ATG7_N; Ubiquitin-like modifier-activating enzyme ATG7 N-terminus
NM_001349233.2 → NP_001336162.1 ubiquitin-like modifier-activating enzyme ATG7 isoform a

Status: REVIEWED

Description

Transcript Variant: This variant (5), as well as variants 1, 4, 6, and 7, encodes the longest isoform (a).

Source sequence(s)

AC020750, AC022001, AC026185, AC083855

Consensus CDS

CCDS2605.1

UniProtKB/Swiss-Prot

B4E170, E9PB95, O95352, Q7L8L0, Q9BWP2, Q9UFH4

UniProtKB/TrEMBL

B2RB57, B3KQM6

Related

ENSP00000509725.1, ENST00000685771.1

Conserved Domains (1) summary

cl25654
Location:15 → 702

ATG7_N; Ubiquitin-like modifier-activating enzyme ATG7 N-terminus
NM_001349234.2 → NP_001336163.1 ubiquitin-like modifier-activating enzyme ATG7 isoform a

Status: REVIEWED

Description

Transcript Variant: This variant (6), as well as variants 1, 4, 5, and 7, encodes the longest isoform (a).

Source sequence(s)

AC020750, AC022001, AC026185, AC083855

Consensus CDS

CCDS2605.1

UniProtKB/Swiss-Prot

B4E170, E9PB95, O95352, Q7L8L0, Q9BWP2, Q9UFH4

UniProtKB/TrEMBL

B2RB57, B3KQM6

Conserved Domains (1) summary

cl25654
Location:15 → 702

ATG7_N; Ubiquitin-like modifier-activating enzyme ATG7 N-terminus
NM_001349235.2 → NP_001336164.1 ubiquitin-like modifier-activating enzyme ATG7 isoform a

Status: REVIEWED

Description

Transcript Variant: This variant (7), as well as variants 1, 4, 5, and 6, encodes the longest isoform (a).

Source sequence(s)

AC020750, AC022001, AC026185, AC083855

Consensus CDS

CCDS2605.1

UniProtKB/Swiss-Prot

B4E170, E9PB95, O95352, Q7L8L0, Q9BWP2, Q9UFH4

UniProtKB/TrEMBL

B2RB57, B3KQM6

Conserved Domains (1) summary

cl25654
Location:15 → 702

ATG7_N; Ubiquitin-like modifier-activating enzyme ATG7 N-terminus
NM_001349236.2 → NP_001336165.1 ubiquitin-like modifier-activating enzyme ATG7 isoform d

Status: REVIEWED

Description

Transcript Variant: This variant (8) encodes isoform d.

Source sequence(s)

AC020750, AC022001, AC026185, AC083855

UniProtKB/TrEMBL

B2RB57, B3KQM6

Conserved Domains (1) summary

cl25654
Location:15 → 663

ATG7_N; Ubiquitin-like modifier-activating enzyme ATG7 N-terminus
NM_001349237.2 → NP_001336166.1 ubiquitin-like modifier-activating enzyme ATG7 isoform e

Status: REVIEWED

Description

Transcript Variant: This variant (9) encodes isoform e.

Source sequence(s)

AC020750, AC022001, AC026185, AC083855

UniProtKB/TrEMBL

B2RB57, B3KQM6

Conserved Domains (1) summary

cl25654
Location:15 → 649

ATG7_N; Ubiquitin-like modifier-activating enzyme ATG7 N-terminus
NM_001349238.2 → NP_001336167.1 ubiquitin-like modifier-activating enzyme ATG7 isoform f

Status: REVIEWED

Description

Transcript Variant: This variant (10) encodes isoform f.

Source sequence(s)

AC020750, AC022001, AC026185, AC083855

Conserved Domains (1) summary

cd01486
Location:46 → 371

Apg7; Apg7 is an E1-like protein, that activates two different ubiquitin-like proteins, Apg12 and Apg8, and assigns them to specific E2 enzymes, Apg10 and Apg3, respectively. This leads to the covalent conjugation of Apg8 with phosphatidylethanolamine, an ...
NM_006395.3 → NP_006386.1 ubiquitin-like modifier-activating enzyme ATG7 isoform a

See identical proteins and their annotated locations for NP_006386.1

Status: REVIEWED

Description

Transcript Variant: This variant (1), as well as variants 4, 5, 6, and 7, encodes the longest isoform (a).

Source sequence(s)

AC022001, AK075221, AL122075, BC000091, DA177126

Consensus CDS

CCDS2605.1

UniProtKB/Swiss-Prot

B4E170, E9PB95, O95352, Q7L8L0, Q9BWP2, Q9UFH4

UniProtKB/TrEMBL

B2RB57, B3KQM6

Related

ENSP00000346437.3, ENST00000354449.7

Conserved Domains (1) summary

cl25654
Location:15 → 702

ATG7_N; Ubiquitin-like modifier-activating enzyme ATG7 N-terminus

RefSeqs of Annotated Genomes: GCF_000001405.40-RS_2024_08

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCh38.p14 Primary Assembly

Genomic

NC_000003.12 Reference GRCh38.p14 Primary Assembly

Range

11272397..11576353

Download

GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

XM_017005548.2 → XP_016861037.1 ubiquitin-like modifier-activating enzyme ATG7 isoform X4

UniProtKB/TrEMBL

B2RB57, B3KQM6

Conserved Domains (3) summary

cd01486
Location:357 → 682

Apg7; Apg7 is an E1-like protein, that activates two different ubiquitin-like proteins, Apg12 and Apg8, and assigns them to specific E2 enzymes, Apg10 and Apg3, respectively. This leads to the covalent conjugation of Apg8 with phosphatidylethanolamine, an ...

TIGR01381
Location:15 → 697

E1_like_apg7; E1-like protein-activating enzyme Gsa7p/Apg7p

pfam16420
Location:13 → 321

ATG7_N; Ubiquitin-like modifier-activating enzyme ATG7 N-terminus
XM_017005551.2 → XP_016861040.1 ubiquitin-like modifier-activating enzyme ATG7 isoform X10

UniProtKB/TrEMBL

B2RB57, B3KQM6
XM_047447304.1 → XP_047303260.1 ubiquitin-like modifier-activating enzyme ATG7 isoform X13

UniProtKB/TrEMBL

B2RB57, B3KQM6
XM_047447296.1 → XP_047303252.1 ubiquitin-like modifier-activating enzyme ATG7 isoform X1

UniProtKB/TrEMBL

B2RB57, B3KQM6
XM_011533277.4 → XP_011531579.1 ubiquitin-like modifier-activating enzyme ATG7 isoform X1

See identical proteins and their annotated locations for XP_011531579.1

UniProtKB/TrEMBL

B2RB57, B3KQM6

Conserved Domains (1) summary

TIGR01381
Location:15 → 693

E1_like_apg7; E1-like protein-activating enzyme Gsa7p/Apg7p
XM_006712932.5 → XP_006712995.1 ubiquitin-like modifier-activating enzyme ATG7 isoform X1

See identical proteins and their annotated locations for XP_006712995.1

UniProtKB/TrEMBL

B2RB57, B3KQM6

Conserved Domains (1) summary

TIGR01381
Location:15 → 693

E1_like_apg7; E1-like protein-activating enzyme Gsa7p/Apg7p
XM_006712931.5 → XP_006712994.1 ubiquitin-like modifier-activating enzyme ATG7 isoform X1

See identical proteins and their annotated locations for XP_006712994.1

UniProtKB/TrEMBL

B2RB57, B3KQM6

Conserved Domains (1) summary

TIGR01381
Location:15 → 693

E1_like_apg7; E1-like protein-activating enzyme Gsa7p/Apg7p
XM_017005543.2 → XP_016861032.1 ubiquitin-like modifier-activating enzyme ATG7 isoform X7

UniProtKB/TrEMBL

B2RB57, B3KQM6

Conserved Domains (3) summary

cd01486
Location:357 → 655

Apg7; Apg7 is an E1-like protein, that activates two different ubiquitin-like proteins, Apg12 and Apg8, and assigns them to specific E2 enzymes, Apg10 and Apg3, respectively. This leads to the covalent conjugation of Apg8 with phosphatidylethanolamine, an ...

TIGR01381
Location:15 → 666

E1_like_apg7; E1-like protein-activating enzyme Gsa7p/Apg7p

pfam16420
Location:13 → 321

ATG7_N; Ubiquitin-like modifier-activating enzyme ATG7 N-terminus
XM_047447301.1 → XP_047303257.1 ubiquitin-like modifier-activating enzyme ATG7 isoform X8

UniProtKB/TrEMBL

B2RB57, B3KQM6
XM_047447303.1 → XP_047303259.1 ubiquitin-like modifier-activating enzyme ATG7 isoform X12

UniProtKB/TrEMBL

B2RB57, B3KQM6
XM_047447294.1 → XP_047303250.1 ubiquitin-like modifier-activating enzyme ATG7 isoform X5

UniProtKB/TrEMBL

B2RB57, B3KQM6
XM_047447302.1 → XP_047303258.1 ubiquitin-like modifier-activating enzyme ATG7 isoform X11

UniProtKB/TrEMBL

B2RB57, B3KQM6
XM_047447305.1 → XP_047303261.1 ubiquitin-like modifier-activating enzyme ATG7 isoform X14

UniProtKB/TrEMBL

B2RB57, B3KQM6
XM_047447293.1 → XP_047303249.1 ubiquitin-like modifier-activating enzyme ATG7 isoform X3

UniProtKB/TrEMBL

B2RB57, B3KQM6
XM_047447300.1 → XP_047303256.1 ubiquitin-like modifier-activating enzyme ATG7 isoform X6

UniProtKB/TrEMBL

B2RB57, B3KQM6
XM_047447306.1 → XP_047303262.1 ubiquitin-like modifier-activating enzyme ATG7 isoform X15

UniProtKB/TrEMBL

B2RB57, B3KQM6
XM_024453312.2 → XP_024309080.1 ubiquitin-like modifier-activating enzyme ATG7 isoform X2

UniProtKB/TrEMBL

B2RB57, B3KQM6

Conserved Domains (1) summary

cl25654
Location:15 → 694

ATG7_N; Ubiquitin-like modifier-activating enzyme ATG7 N-terminus
XM_017005550.2 → XP_016861039.1 ubiquitin-like modifier-activating enzyme ATG7 isoform X9

UniProtKB/TrEMBL

B2RB57, B3KQM6
XM_047447298.1 → XP_047303254.1 ubiquitin-like modifier-activating enzyme ATG7 isoform X1

UniProtKB/TrEMBL

B2RB57, B3KQM6
XM_047447295.1 → XP_047303251.1 ubiquitin-like modifier-activating enzyme ATG7 isoform X1

UniProtKB/TrEMBL

B2RB57, B3KQM6
XM_047447299.1 → XP_047303255.1 ubiquitin-like modifier-activating enzyme ATG7 isoform X1

UniProtKB/TrEMBL

B2RB57, B3KQM6
XM_047447297.1 → XP_047303253.1 ubiquitin-like modifier-activating enzyme ATG7 isoform X1

UniProtKB/TrEMBL

B2RB57, B3KQM6
XM_017005542.2 → XP_016861031.1 ubiquitin-like modifier-activating enzyme ATG7 isoform X1

UniProtKB/TrEMBL

B2RB57, B3KQM6

Conserved Domains (1) summary

TIGR01381
Location:15 → 693

E1_like_apg7; E1-like protein-activating enzyme Gsa7p/Apg7p
XM_047447307.1 → XP_047303263.1 ubiquitin-like modifier-activating enzyme ATG7 isoform X16
XM_047447308.1 → XP_047303264.1 ubiquitin-like modifier-activating enzyme ATG7 isoform X17
XM_047447309.1 → XP_047303265.1 ubiquitin-like modifier-activating enzyme ATG7 isoform X18

RNA

XR_007095622.1 RNA Sequence
XR_007095623.1 RNA Sequence

Alternate T2T-CHM13v2.0

Genomic

NC_060927.1 Alternate T2T-CHM13v2.0

Range

11267348..11571596

Download

GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

XM_054344946.1 → XP_054200921.1 ubiquitin-like modifier-activating enzyme ATG7 isoform X4

UniProtKB/TrEMBL

B2RB57, B3KQM6
XM_054344952.1 → XP_054200927.1 ubiquitin-like modifier-activating enzyme ATG7 isoform X10

UniProtKB/TrEMBL

B2RB57, B3KQM6
XM_054344955.1 → XP_054200930.1 ubiquitin-like modifier-activating enzyme ATG7 isoform X13

UniProtKB/TrEMBL

B2RB57, B3KQM6
XM_054344939.1 → XP_054200914.1 ubiquitin-like modifier-activating enzyme ATG7 isoform X1

UniProtKB/TrEMBL

B2RB57, B3KQM6
XM_054344954.1 → XP_054200929.1 ubiquitin-like modifier-activating enzyme ATG7 isoform X12

UniProtKB/TrEMBL

B2RB57, B3KQM6
XM_054344948.1 → XP_054200923.1 ubiquitin-like modifier-activating enzyme ATG7 isoform X5

UniProtKB/TrEMBL

B2RB57, B3KQM6
XM_054344953.1 → XP_054200928.1 ubiquitin-like modifier-activating enzyme ATG7 isoform X11

UniProtKB/TrEMBL

B2RB57, B3KQM6
XM_054344956.1 → XP_054200931.1 ubiquitin-like modifier-activating enzyme ATG7 isoform X14

UniProtKB/TrEMBL

B2RB57, B3KQM6
XM_054344947.1 → XP_054200922.1 ubiquitin-like modifier-activating enzyme ATG7 isoform X20

UniProtKB/TrEMBL

B2RB57, B3KQM6
XM_054344950.1 → XP_054200925.1 ubiquitin-like modifier-activating enzyme ATG7 isoform X21

UniProtKB/TrEMBL

B2RB57, B3KQM6
XM_054344942.1 → XP_054200917.1 ubiquitin-like modifier-activating enzyme ATG7 isoform X19

UniProtKB/TrEMBL

B2RB57, B3KQM6
XM_054344943.1 → XP_054200918.1 ubiquitin-like modifier-activating enzyme ATG7 isoform X19

UniProtKB/TrEMBL

B2RB57, B3KQM6
XM_054344938.1 → XP_054200913.1 ubiquitin-like modifier-activating enzyme ATG7 isoform X19

UniProtKB/TrEMBL

B2RB57, B3KQM6
XM_054344949.1 → XP_054200924.1 ubiquitin-like modifier-activating enzyme ATG7 isoform X6

UniProtKB/TrEMBL

B2RB57, B3KQM6
XM_054344957.1 → XP_054200932.1 ubiquitin-like modifier-activating enzyme ATG7 isoform X15

UniProtKB/TrEMBL

B2RB57, B3KQM6
XM_054344951.1 → XP_054200926.1 ubiquitin-like modifier-activating enzyme ATG7 isoform X9

UniProtKB/TrEMBL

B2RB57, B3KQM6
XM_054344940.1 → XP_054200915.1 ubiquitin-like modifier-activating enzyme ATG7 isoform X2

UniProtKB/TrEMBL

B2RB57, B3KQM6
XM_054344941.1 → XP_054200916.1 ubiquitin-like modifier-activating enzyme ATG7 isoform X19

UniProtKB/TrEMBL

B2RB57, B3KQM6
XM_054344944.1 → XP_054200919.1 ubiquitin-like modifier-activating enzyme ATG7 isoform X19

UniProtKB/TrEMBL

B2RB57, B3KQM6
XM_054344945.1 → XP_054200920.1 ubiquitin-like modifier-activating enzyme ATG7 isoform X19

UniProtKB/TrEMBL

B2RB57, B3KQM6
XM_054344958.1 → XP_054200933.1 ubiquitin-like modifier-activating enzyme ATG7 isoform X22
XM_054344959.1 → XP_054200934.1 ubiquitin-like modifier-activating enzyme ATG7 isoform X17
XM_054344960.1 → XP_054200935.1 ubiquitin-like modifier-activating enzyme ATG7 isoform X23