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These reference sequences exist independently of genome builds. Explain
These reference sequences are curated independently of the genome
annotation cycle, so their versions may not match the RefSeq versions in the current
genome build. Identify version mismatches by comparing the version of the RefSeq in
this section to the one reported in Genomic regions,
transcripts, and products above.
mRNA and Protein(s)
-
NM_001126050.2 → NP_001119522.1 hepatoma-derived growth factor isoform b
Status: REVIEWED
- Description
- Transcript Variant: This variant (2) differs uses an alternate in-frame splice junction compared to variant 4. The resulting isoform (b) has the same N- and C-termini but is shorter compared to isoform d.
- Source sequence(s)
-
AL590666
- Consensus CDS
-
CCDS44247.1
- UniProtKB/TrEMBL
-
B7Z958
- Related
- ENSP00000357189.5, ENST00000368206.5
- Conserved Domains (1) summary
-
- cl02554
Location:40 → 108
- PWWP; The PWWP domain, named for a conserved Pro-Trp-Trp-Pro motif, is a small domain consisting of 100-150 amino acids. The PWWP domain is found in numerous proteins that are involved in cell division, growth and differentiation. Most PWWP-domain proteins ...
-
NM_001126051.1 → NP_001119523.1 hepatoma-derived growth factor isoform c
See identical proteins and their annotated locations for NP_001119523.1
Status: REVIEWED
- Description
- Transcript Variant: This variant (3) differs in the 5' UTR and coding sequence and uses an alternate in-frame splice junction compared to variant 4. The resulting isoform (c) has a shorter and distinct N-terminus and lacks an alternate internal segment compared to isoform d.
- Source sequence(s)
-
AL590666, D16431, DA207052, DA367806, F36780
- Consensus CDS
-
CCDS44248.1
- UniProtKB/TrEMBL
-
B7Z958
- Related
- ENSP00000357192.5, ENST00000368209.9
- Conserved Domains (1) summary
-
- cl02554
Location:21 → 85
- PWWP; The PWWP domain, named for a conserved Pro-Trp-Trp-Pro motif, is a small domain consisting of 100-150 amino acids. The PWWP domain is found in numerous proteins that are involved in cell division, growth and differentiation. Most PWWP-domain proteins ...
-
NM_001319186.2 → NP_001306115.1 hepatoma-derived growth factor isoform d
Status: REVIEWED
- Description
- Transcript Variant: This variant (4) encodes the longest isoform (d).
- Source sequence(s)
-
AL590666
- UniProtKB/TrEMBL
-
B7Z958
- Conserved Domains (1) summary
-
- cl02554
Location:40 → 108
- PWWP; The PWWP domain, named for a conserved Pro-Trp-Trp-Pro motif, is a small domain consisting of 100-150 amino acids. The PWWP domain is found in numerous proteins that are involved in cell division, growth and differentiation. Most PWWP-domain proteins ...
-
NM_001319187.2 → NP_001306116.1 hepatoma-derived growth factor isoform e
Status: REVIEWED
- Description
- Transcript Variant: This variant (5) differs in the 5' UTR and coding sequence and uses an alternate in-frame splice junction compared to variant 4. The resulting isoform (e) is shorter at the N-terminus and lacks an alternate internal segment compared to isoform d. Variants 5 and 6 both encode the same isoform (e).
- Source sequence(s)
-
AL590666
- UniProtKB/TrEMBL
- A8K8G0, B7Z958
- Conserved Domains (1) summary
-
- cl02554
Location:7 → 60
- PWWP; The PWWP domain, named for a conserved Pro-Trp-Trp-Pro motif, is a small domain consisting of 100-150 amino acids. The PWWP domain is found in numerous proteins that are involved in cell division, growth and differentiation. Most PWWP-domain proteins ...
-
NM_001319188.2 → NP_001306117.1 hepatoma-derived growth factor isoform e
Status: REVIEWED
- Description
- Transcript Variant: This variant (6) differs in the 5' UTR and coding sequence and uses an alternate in-frame splice junction compared to variant 4. The resulting isoform (e) is shorter at the N-terminus and lacks an alternate internal segment compared to isoform d. Variants 5 and 6 both encode the same isoform (e).
- Source sequence(s)
-
AL590666
- UniProtKB/TrEMBL
- A8K8G0, B7Z958
- Conserved Domains (1) summary
-
- cl02554
Location:7 → 60
- PWWP; The PWWP domain, named for a conserved Pro-Trp-Trp-Pro motif, is a small domain consisting of 100-150 amino acids. The PWWP domain is found in numerous proteins that are involved in cell division, growth and differentiation. Most PWWP-domain proteins ...
-
NM_004494.3 → NP_004485.1 hepatoma-derived growth factor isoform a
See identical proteins and their annotated locations for NP_004485.1
Status: REVIEWED
- Description
- Transcript Variant: This variant (1) differs in the 5' UTR and coding sequence and uses an alternate in-frame splice junction compared to variant 4. The resulting isoform (a) has a shorter and distinct N-terminus and lacks an alternate internal segment compared to isoform d.
- Source sequence(s)
-
AL590666
- Consensus CDS
-
CCDS1156.1
- UniProtKB/Swiss-Prot
- B3KU21, D3DVC9, P51858, Q5SZ07, Q5SZ08, Q5SZ09
- UniProtKB/TrEMBL
- A0A384NPW1, B2RDE8
- Related
- ENSP00000349878.5, ENST00000357325.10
- Conserved Domains (1) summary
-
- cd05834
Location:8 → 92
- HDGF_related; The PWWP domain is an essential part of the Hepatoma Derived Growth Factor (HDGF) family of proteins, and is necessary for DNA binding by HDGF. This family of endogenous nuclear-targeted mitogens includes HRP (HDGF-related proteins 1, 2, 3, 4, or HPR1, ...
RNA
-
NR_135008.2 RNA Sequence
Status: REVIEWED
- Description
- Transcript Variant: This variant (7) contains an alternate exon and uses an alternate splice junction compared to variant 4. This variant is represented as non-coding because the use of the 5'-most expected translational start codon renders the transcript a candidate for nonsense-mediated mRNA decay (NMD).
- Source sequence(s)
-
AL590666
The following sections contain reference sequences that belong to a
specific genome build. Explain
This section includes genomic Reference
Sequences (RefSeqs) from all assemblies on which this gene is annotated, such as
RefSeqs for chromosomes and scaffolds (contigs) from both reference and alternate
assemblies. Model RNAs and proteins are also reported here.
Reference GRCh38.p14 Primary Assembly
Genomic
-
NC_000001.11 Reference GRCh38.p14 Primary Assembly
- Range
-
156742107..156767366 complement
- Download
- GenBank, FASTA, Sequence Viewer (Graphics)
mRNA and Protein(s)
-
XM_047418832.1 → XP_047274788.1 hepatoma-derived growth factor isoform X1
- UniProtKB/TrEMBL
- A8K8G0, B7Z958
-
XM_047418831.1 → XP_047274787.1 hepatoma-derived growth factor isoform X1
- UniProtKB/TrEMBL
- A8K8G0, B7Z958
- Related
-
ENST00000465180.5
-
XM_047418833.1 → XP_047274789.1 hepatoma-derived growth factor isoform X1
- UniProtKB/TrEMBL
- A8K8G0, B7Z958
-
XM_011509455.3 → XP_011507757.1 hepatoma-derived growth factor isoform X1
See identical proteins and their annotated locations for XP_011507757.1
- UniProtKB/TrEMBL
- A8K8G0, B7Z958
- Conserved Domains (1) summary
-
- cl02554
Location:7 → 60
- PWWP; The PWWP domain, named for a conserved Pro-Trp-Trp-Pro motif, is a small domain consisting of 100-150 amino acids. The PWWP domain is found in numerous proteins that are involved in cell division, growth and differentiation. Most PWWP-domain proteins ...
-
XM_011509454.3 → XP_011507756.1 hepatoma-derived growth factor isoform X1
See identical proteins and their annotated locations for XP_011507756.1
- UniProtKB/TrEMBL
- A8K8G0, B7Z958
- Conserved Domains (1) summary
-
- cl02554
Location:7 → 60
- PWWP; The PWWP domain, named for a conserved Pro-Trp-Trp-Pro motif, is a small domain consisting of 100-150 amino acids. The PWWP domain is found in numerous proteins that are involved in cell division, growth and differentiation. Most PWWP-domain proteins ...
-
XM_011509453.3 → XP_011507755.2 hepatoma-derived growth factor isoform X1
- UniProtKB/TrEMBL
- A8K8G0, B7Z958
- Conserved Domains (1) summary
-
- cl02554
Location:7 → 60
- PWWP; The PWWP domain, named for a conserved Pro-Trp-Trp-Pro motif, is a small domain consisting of 100-150 amino acids. The PWWP domain is found in numerous proteins that are involved in cell division, growth and differentiation. Most PWWP-domain proteins ...
Alternate T2T-CHM13v2.0
Genomic
-
NC_060925.1 Alternate T2T-CHM13v2.0
- Range
-
155878940..155904217 complement
- Download
- GenBank, FASTA, Sequence Viewer (Graphics)
mRNA and Protein(s)
-
XM_054336208.1 → XP_054192183.1 hepatoma-derived growth factor isoform X1
- UniProtKB/TrEMBL
- A8K8G0, B7Z958
-
XM_054336207.1 → XP_054192182.1 hepatoma-derived growth factor isoform X1
- UniProtKB/TrEMBL
- A8K8G0, B7Z958
-
XM_054336209.1 → XP_054192184.1 hepatoma-derived growth factor isoform X1
- UniProtKB/TrEMBL
- A8K8G0, B7Z958
-
XM_054336205.1 → XP_054192180.1 hepatoma-derived growth factor isoform X1
- UniProtKB/TrEMBL
- A8K8G0, B7Z958
-
XM_054336206.1 → XP_054192181.1 hepatoma-derived growth factor isoform X1
- UniProtKB/TrEMBL
- A8K8G0, B7Z958
-
XM_054336204.1 → XP_054192179.1 hepatoma-derived growth factor isoform X1
- UniProtKB/TrEMBL
- A8K8G0, B7Z958