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    Phf11d PHD finger protein 11D [ Mus musculus (house mouse) ]

    Gene ID: 219132, updated on 27-Nov-2024

    Summary

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    Official Symbol
    Phf11dprovided by MGI
    Official Full Name
    PHD finger protein 11Dprovided by MGI
    Primary source
    MGI:MGI:1277133
    See related
    Ensembl:ENSMUSG00000068245 AllianceGenome:MGI:1277133
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Mus musculus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
    Also known as
    Phf11; Phf11l; D14Ertd668e
    Summary
    Predicted to enable metal ion binding activity. Predicted to be located in nuclear membrane and nucleoplasm. Predicted to be active in nucleus. Is expressed in alimentary system; axial musculature; orbito-sphenoid; submandibular gland primordium; and vibrissa. Orthologous to human PHF11 (PHD finger protein 11). [provided by Alliance of Genome Resources, Nov 2024]
    Expression
    Broad expression in bladder adult (RPKM 3.9), mammary gland adult (RPKM 3.6) and 22 other tissues See more
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    Genomic context

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    See Phf11d in Genome Data Viewer
    Location:
    14 C3; 14 31.48 cM
    Exon count:
    12
    Annotation release Status Assembly Chr Location
    RS_2024_02 current GRCm39 (GCF_000001635.27) 14 NC_000080.7 (59584646..59608004, complement)
    108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 14 NC_000080.6 (59347407..59365490, complement)

    Chromosome 14 - NC_000080.7Genomic Context describing neighboring genes Neighboring gene PHD finger protein 11A Neighboring gene STARR-positive B cell enhancer mm9_chr14:59916339-59916640 Neighboring gene PHD finger protein 11B Neighboring gene STARR-positive B cell enhancer ABC_E11570 Neighboring gene STARR-seq mESC enhancer starr_36838 Neighboring gene STARR-seq mESC enhancer starr_36839 Neighboring gene predicted gene, 45935 Neighboring gene PHD finger protein 11C Neighboring gene SET domain, bifurcated 2 Neighboring gene STARR-positive B cell enhancer ABC_E4112

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Expression

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    • Project title: Mouse ENCODE transcriptome data
    • Description: RNA profiling data sets generated by the Mouse ENCODE project.
    • BioProject: PRJNA66167
    • Publication: PMID 25409824
    • Analysis date: n/a

    Bibliography

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    Related articles in PubMed

    1. Functional analysis of a novel ENU-induced PHD finger 11 (Phf11) mouse mutant. Zhang Y, et al. Mamm Genome, 2014 Dec. PMID 25091723, Free PMC Article
    2. A novel view of the transcriptome revealed from gene trapping in mouse embryonic stem cells. Roma G, et al. Genome Res, 2007 Jul. PMID 17540781, Free PMC Article
    3. A comparison of whole-genome shotgun-derived mouse chromosome 16 and the human genome. Mural RJ, et al. Science, 2002 May 31. PMID 12040188
    4. Identification of transcripts with enriched expression in the developing and adult pancreas. Hoffman BG, et al. Genome Biol, 2008. PMID 18554416, Free PMC Article
    5. Large-scale cDNA analysis reveals phased gene expression patterns during preimplantation mouse development. Ko MS, et al. Development, 2000 Apr. PMID 10725249

    See all (18) citations in PubMed

    GeneRIFs: Gene References Into Functions

    What's a GeneRIF?
    1. Only Phf11d is present in multiple mouse tissue cDNAs.
      Title: Functional analysis of a novel ENU-induced PHD finger 11 (Phf11) mouse mutant.
    Submit: New GeneRIF Correction

    Variation

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    Alleles

    Alleles of this type are documented at Mouse Genome Informatics  (MGI)
    • Chemically induced (ENU) (1)  1 citation
    • Endonuclease-mediated (1) 

    General gene information

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    Markers

    Readthrough Gm45935

    Readthrough gene: Gm45935, Included gene: Setdb2, Included gene: Phf11c

    Homology

    Clone Names

    • MGC29273

    Gene Ontology Provided by MGI

    Function Evidence Code Pubs
    enables metal ion binding IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables molecular_function ND
    No biological Data available
    more info
    		  
    Process Evidence Code Pubs
    involved_in biological_process ND
    No biological Data available
    more info
    		  
    Component Evidence Code Pubs
    located_in nuclear membrane ISO
    Inferred from Sequence Orthology
    more info
    		  
    located_in nucleoplasm ISO
    Inferred from Sequence Orthology
    more info
    		  
    is_active_in nucleus IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    located_in nucleus IEA
    Inferred from Electronic Annotation
    more info
    		  

    General protein information

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    Preferred Names
    PHD finger protein 11
    Names
    PHD finger protein 11 family member

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001419878.1 → NP_001406807.1  PHD finger protein 11 isoform 1

      Status: VALIDATED

      Source sequence(s)
      AC114007
      UniProtKB/Swiss-Prot
      A6H5X4, Q3U0T6, Q8K2R8
      Related
      ENSMUSP00000125181.2, ENSMUST00000161031.2

    2. NM_001419879.1 → NP_001406808.1  PHD finger protein 11 isoform 3

      Status: VALIDATED

      Source sequence(s)
      AC114007

    3. NM_001419880.1 → NP_001406809.1  PHD finger protein 11 isoform 4

      Status: VALIDATED

      Source sequence(s)
      AC114007

    4. NM_001419881.1 → NP_001406810.1  PHD finger protein 11 isoform 5

      Status: VALIDATED

      Source sequence(s)
      AC114007

    5. NM_001419882.1 → NP_001406811.1  PHD finger protein 11 isoform 6

      Status: VALIDATED

      Source sequence(s)
      AC114007

    6. NM_001419883.1 → NP_001406812.1  PHD finger protein 11 isoform 7

      Status: VALIDATED

      Source sequence(s)
      AC114007

    7. NM_001419884.1 → NP_001406813.1  PHD finger protein 11 isoform 8

      Status: VALIDATED

      Source sequence(s)
      AC114007
      Related
      ENSMUSP00000124578.2, ENSMUST00000160425.8

    8. NM_001419885.1 → NP_001406814.1  PHD finger protein 11 isoform 9

      Status: VALIDATED

      Source sequence(s)
      AC114007

    9. NM_001419886.1 → NP_001406815.1  PHD finger protein 11 isoform 10

      Status: VALIDATED

      Source sequence(s)
      AC114007

    10. NM_001419887.1 → NP_001406816.1  PHD finger protein 11 isoform 11

      Status: VALIDATED

      Source sequence(s)
      AC114007

    11. NM_199015.5 → NP_950180.3  PHD finger protein 11 isoform 2

      See identical proteins and their annotated locations for NP_950180.3

      Status: VALIDATED

      Source sequence(s)
      AC114007
      Consensus CDS
      CCDS27170.3
      UniProtKB/Swiss-Prot
      A6H5X4
      UniProtKB/TrEMBL
      B4XVQ0
      Related
      ENSMUSP00000092779.5, ENSMUST00000095157.11
      Conserved Domains (1) summary
      cl22851
      Location:28 → 142
      PHD_SF; PHD finger superfamily

    RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCm39 C57BL/6J

    Genomic

    1. NC_000080.7 Reference GRCm39 C57BL/6J

      Range
      59584646..59608004 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    Suppressed Reference Sequence(s)

    The following Reference Sequences have been suppressed. Explain

    1. NM_001164323.1: Suppressed sequence

      Description
      NM_001164323.1: This RefSeq was permanently suppressed because currently there is insufficient support for the transcript and the protein.
    Nucleotide Protein Strain
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    A6H5X4.1 GenPept UniProtKB/Swiss-Prot:A6H5X4

    Gene LinkOut

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