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    Tmbim7 transmembrane BAX inhibitor motif containing 7 [ Rattus norvegicus (Norway rat) ]

    Gene ID: 362319, updated on 9-Dec-2024

    Summary

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    Official Symbol
    Tmbim7provided by RGD
    Official Full Name
    transmembrane BAX inhibitor motif containing 7provided by RGD
    Primary source
    RGD:1306626
    See related
    EnsemblRapid:ENSRNOG00000008585 AllianceGenome:RGD:1306626
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Rattus norvegicus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
    Also known as
    RGD1306626
    Summary
    Predicted to enable calcium channel activity. Predicted to be active in Golgi apparatus and membrane. Orthologous to human TMBIM7P (transmembrane BAX inhibitor motif containing 7, pseudogene). [provided by Alliance of Genome Resources, Dec 2024]
    Expression
    Restricted expression toward (RPKM 399.8) See more
    Orthologs
    mouse all
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    Genomic context

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    See Tmbim7 in Genome Data Viewer
    Location:
    4q13
    Exon count:
    11
    Annotation release Status Assembly Chr Location
    RS_2024_02 current GRCr8 (GCF_036323735.1) 4 NC_086022.1 (31421371..31454319, complement)
    RS_2023_06 previous assembly mRatBN7.2 (GCF_015227675.2) 4 NC_051339.1 (30466651..30499565, complement)
    106 previous assembly Rnor_6.0 (GCF_000001895.5) 4 NC_005103.4 (27606049..27639025, complement)

    Chromosome 4 - NC_086022.1Genomic Context describing neighboring genes Neighboring gene uncharacterized LOC134486560 Neighboring gene KRIT1, ankyrin repeat containing Neighboring gene ankyrin repeat and IBR domain containing 1 Neighboring gene DND microRNA-mediated repression inhibitor 1, pseudogene 2 Neighboring gene GATA zinc finger domain containing 1 Neighboring gene peroxisomal biogenesis factor 1

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Expression

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    • Project title: A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages
    • Description: 320 RNA samples isolated from 11 organs (adrenal gland, brain, heart, kidney, liver, lung, muscle, spleen, thymus, and testes or uterus) from both sexes of Fischer 344 rats across four developmental stages (2-, 6-, 21-, and 104-weeks-old)
    • BioProject: PRJNA238328
    • Publication: PMID 24510058
    • Analysis date: Mon Jun 6 17:44:12 2016

    Bibliography

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    Related articles in PubMed

    1. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. Strausberg RL, et al. Proc Natl Acad Sci U S A, 2002 Dec 24. PMID 12477932, Free PMC Article
    2. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, et al. Brief Bioinform, 2011 Sep. PMID 21873635, Free PMC Article

    GeneRIFs: Gene References Into Functions

    General gene information

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    Homology

    Clone Names

    • MGC125025

    Gene Ontology Provided by RGD

    Function Evidence Code Pubs
    enables calcium channel activity IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    Process Evidence Code Pubs
    involved_in calcium ion transmembrane transport IEA
    Inferred from Electronic Annotation
    more info
    		  
    Component Evidence Code Pubs
    is_active_in Golgi apparatus IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    is_active_in membrane IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  

    General protein information

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    Preferred Names
    bax inhibitor 1-like

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001039612.2 → NP_001034701.2  bax inhibitor 1-like

      See identical proteins and their annotated locations for NP_001034701.2

      Status: VALIDATED

      Source sequence(s)
      BC105862
      UniProtKB/TrEMBL
      A6K281, F1LS63, Q3KR74
      Related
      ENSRNOP00000011377.6, ENSRNOT00000011377.7
      Conserved Domains (1) summary
      cd10428
      Location:85 → 302
      LFG_like; Proteins similar to and including lifeguard (LFG), a putative regulator of apoptosis

    RefSeqs of Annotated Genomes: GCF_036323735.1-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCr8

    Genomic

    1. NC_086022.1 Reference GRCr8

      Range
      31421371..31454319 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_006236047.5 → XP_006236109.1  bax inhibitor 1-like isoform X1

      UniProtKB/TrEMBL
      Q3KR74
      Conserved Domains (1) summary
      cd10428
      Location:85 → 272
      LFG_like; Proteins similar to and including lifeguard (LFG), a putative regulator of apoptosis
    Nucleotide Protein Strain
    Heading Accession and Version

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