U.S. flag

An official website of the United States government

Format

Send to:

Choose Destination

Links from GEO Profiles

    • Showing Current items.

    Ttll13 tubulin tyrosine ligase-like family, member 13 [ Mus musculus (house mouse) ]

    Gene ID: 269954, updated on 9-Dec-2024

    Summary

    Official Symbol
    Ttll13provided by MGI
    Official Full Name
    tubulin tyrosine ligase-like family, member 13provided by MGI
    Primary source
    MGI:MGI:1920845
    See related
    Ensembl:ENSMUSG00000045467 AllianceGenome:MGI:1920845
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Mus musculus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
    Also known as
    4921538O11; 1700111A04Rik
    Summary
    Enables tubulin-glutamic acid ligase activity. Predicted to be involved in microtubule bundle formation. Predicted to be located in microtubule. Predicted to be active in ciliary basal body. Is expressed in 1-cell stage embryo and 8-cell stage embryo. Orthologous to human TTLL13 (tubulin tyrosine ligase like 13). [provided by Alliance of Genome Resources, Dec 2024]
    Expression
    Restricted expression toward testis adult (RPKM 120.2) See more
    Orthologs
    NEW
    Try the new Gene table
    Try the new Transcript table

    Genomic context

    See Ttll13 in Genome Data Viewer
    Location:
    7 D2; 7 45.57 cM
    Exon count:
    15
    Annotation release Status Assembly Chr Location
    RS_2024_02 current GRCm39 (GCF_000001635.27) 7 NC_000073.7 (79896101..79910569)
    108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 7 NC_000073.6 (80246353..80260821)

    Chromosome 7 - NC_000073.7Genomic Context describing neighboring genes Neighboring gene STARR-positive B cell enhancer ABC_E10446 Neighboring gene calcium and integrin binding 1 Neighboring gene GDP-D-glucose phosphorylase 1 Neighboring gene STARR-positive B cell enhancer ABC_E4940 Neighboring gene neugrin, neurite outgrowth associated Neighboring gene STARR-positive B cell enhancer ABC_E2826 Neighboring gene vacuolar protein sorting 33B

    Genomic regions, transcripts, and products

    Expression

    • Project title: Mouse ENCODE transcriptome data
    • Description: RNA profiling data sets generated by the Mouse ENCODE project.
    • BioProject: PRJNA66167
    • Publication: PMID 25409824
    • Analysis date: n/a

    Variation

    Alleles

    Alleles of this type are documented at Mouse Genome Informatics  (MGI)
    • Endonuclease-mediated (1) 
    • Gene trapped (2) 

    Interactions

    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

    Markers

    Gene Ontology Provided by MGI

    Function Evidence Code Pubs
    enables ATP binding IEA
    Inferred from Electronic Annotation
    more info
     
    enables metal ion binding IEA
    Inferred from Electronic Annotation
    more info
     
    enables protein-glutamic acid ligase activity, elongating IEA
    Inferred from Electronic Annotation
    more info
     
    enables tubulin binding IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    enables tubulin-glutamic acid ligase activity IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    enables tubulin-glutamic acid ligase activity IDA
    Inferred from Direct Assay
    more info
    PubMed 
    Process Evidence Code Pubs
    involved_in microtubule bundle formation IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    involved_in protein modification process IEA
    Inferred from Electronic Annotation
    more info
     
    Component Evidence Code Pubs
    is_active_in ciliary basal body IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    located_in microtubule IEA
    Inferred from Electronic Annotation
    more info
     

    General protein information

    Preferred Names
    tubulin polyglutamylase TTLL13
    Names
    tubulin--tyrosine ligase-like protein 13

    NCBI Reference Sequences (RefSeq)

    NEW Try the new Transcript table

    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001396015.1NP_001382944.1  tubulin polyglutamylase TTLL13 isoform 1

      Status: VALIDATED

      Source sequence(s)
      AC109232
      UniProtKB/TrEMBL
      A6H647
      Related
      ENSMUSP00000145702.2, ENSMUST00000205270.2
      Conserved Domains (1) summary
      pfam03133
      Location:133418
      TTL; Tubulin-tyrosine ligase family
    2. NM_177765.4NP_808433.2  tubulin polyglutamylase TTLL13 isoform 2

      See identical proteins and their annotated locations for NP_808433.2

      Status: VALIDATED

      Source sequence(s)
      AC109232
      Consensus CDS
      CCDS39996.1
      UniProtKB/Swiss-Prot
      A4Q9F6, Q8C0W9
      UniProtKB/TrEMBL
      A6H647
      Related
      ENSMUSP00000062795.7, ENSMUST00000058266.9
      Conserved Domains (1) summary
      pfam03133
      Location:133418
      TTL; Tubulin-tyrosine ligase family

    RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCm39 C57BL/6J

    Genomic

    1. NC_000073.7 Reference GRCm39 C57BL/6J

      Range
      79896101..79910569
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_006540925.4XP_006540988.2  tubulin polyglutamylase TTLL13 isoform X7

      UniProtKB/TrEMBL
      A6H647
      Conserved Domains (2) summary
      TIGR03185
      Location:383552
      DNA_S_dndD; DNA sulfur modification protein DndD
      pfam03133
      Location:71356
      TTL; Tubulin-tyrosine ligase family
    2. XM_030242619.1XP_030098479.1  tubulin polyglutamylase TTLL13 isoform X7

      UniProtKB/TrEMBL
      A6H647
      Conserved Domains (2) summary
      TIGR03185
      Location:383552
      DNA_S_dndD; DNA sulfur modification protein DndD
      pfam03133
      Location:71356
      TTL; Tubulin-tyrosine ligase family
    3. XM_030242621.2XP_030098481.1  tubulin polyglutamylase TTLL13 isoform X11

      UniProtKB/TrEMBL
      A6H647
      Conserved Domains (2) summary
      TIGR03185
      Location:340509
      DNA_S_dndD; DNA sulfur modification protein DndD
      pfam03133
      Location:28313
      TTL; Tubulin-tyrosine ligase family
    4. XM_006540914.5XP_006540977.1  tubulin polyglutamylase TTLL13 isoform X1

      See identical proteins and their annotated locations for XP_006540977.1

      UniProtKB/TrEMBL
      A6H647
      Conserved Domains (2) summary
      TIGR03185
      Location:466635
      DNA_S_dndD; DNA sulfur modification protein DndD
      pfam03133
      Location:154439
      TTL; Tubulin-tyrosine ligase family
    5. XM_006540915.5XP_006540978.1  tubulin polyglutamylase TTLL13 isoform X1

      See identical proteins and their annotated locations for XP_006540978.1

      UniProtKB/TrEMBL
      A6H647
      Conserved Domains (2) summary
      TIGR03185
      Location:466635
      DNA_S_dndD; DNA sulfur modification protein DndD
      pfam03133
      Location:154439
      TTL; Tubulin-tyrosine ligase family
    6. XM_006540913.5XP_006540976.1  tubulin polyglutamylase TTLL13 isoform X1

      See identical proteins and their annotated locations for XP_006540976.1

      UniProtKB/TrEMBL
      A6H647
      Conserved Domains (2) summary
      TIGR03185
      Location:466635
      DNA_S_dndD; DNA sulfur modification protein DndD
      pfam03133
      Location:154439
      TTL; Tubulin-tyrosine ligase family
    7. XM_006540918.5XP_006540981.1  tubulin polyglutamylase TTLL13 isoform X4

      UniProtKB/TrEMBL
      A6H647
      Conserved Domains (2) summary
      TIGR03185
      Location:466635
      DNA_S_dndD; DNA sulfur modification protein DndD
      pfam03133
      Location:154439
      TTL; Tubulin-tyrosine ligase family
    8. XM_006540920.5XP_006540983.1  tubulin polyglutamylase TTLL13 isoform X8

      See identical proteins and their annotated locations for XP_006540983.1

      Conserved Domains (2) summary
      TIGR03185
      Location:466635
      DNA_S_dndD; DNA sulfur modification protein DndD
      pfam03133
      Location:154439
      TTL; Tubulin-tyrosine ligase family
    9. XM_006540921.5XP_006540984.1  tubulin polyglutamylase TTLL13 isoform X8

      See identical proteins and their annotated locations for XP_006540984.1

      Conserved Domains (2) summary
      TIGR03185
      Location:466635
      DNA_S_dndD; DNA sulfur modification protein DndD
      pfam03133
      Location:154439
      TTL; Tubulin-tyrosine ligase family
    10. XM_006540916.5XP_006540979.1  tubulin polyglutamylase TTLL13 isoform X2

      UniProtKB/TrEMBL
      A6H647
      Conserved Domains (2) summary
      TIGR03185
      Location:466632
      DNA_S_dndD; DNA sulfur modification protein DndD
      pfam03133
      Location:154439
      TTL; Tubulin-tyrosine ligase family
    11. XM_036153142.1XP_036009035.1  tubulin polyglutamylase TTLL13 isoform X6

      UniProtKB/TrEMBL
      A6H647
      Conserved Domains (1) summary
      pfam03133
      Location:154439
      TTL; Tubulin-tyrosine ligase family
    12. XM_030242620.2XP_030098480.1  tubulin polyglutamylase TTLL13 isoform X9

      Conserved Domains (2) summary
      TIGR03185
      Location:466632
      DNA_S_dndD; DNA sulfur modification protein DndD
      pfam03133
      Location:154439
      TTL; Tubulin-tyrosine ligase family
    13. XM_006540917.5XP_006540980.1  tubulin polyglutamylase TTLL13 isoform X3

      UniProtKB/TrEMBL
      A6H647
      Conserved Domains (2) summary
      TIGR03185
      Location:445614
      DNA_S_dndD; DNA sulfur modification protein DndD
      pfam03133
      Location:133418
      TTL; Tubulin-tyrosine ligase family
    14. XM_006540922.5XP_006540985.1  tubulin polyglutamylase TTLL13 isoform X10

      UniProtKB/TrEMBL
      A6H647
      Conserved Domains (2) summary
      TIGR03185
      Location:361530
      DNA_S_dndD; DNA sulfur modification protein DndD
      pfam03133
      Location:49334
      TTL; Tubulin-tyrosine ligase family
    15. XM_017322293.3XP_017177782.1  tubulin polyglutamylase TTLL13 isoform X11

      UniProtKB/TrEMBL
      A6H647
      Conserved Domains (2) summary
      TIGR03185
      Location:340509
      DNA_S_dndD; DNA sulfur modification protein DndD
      pfam03133
      Location:28313
      TTL; Tubulin-tyrosine ligase family