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    Cd83 CD83 antigen [ Mus musculus (house mouse) ]

    Gene ID: 12522, updated on 9-Dec-2024

    Summary

    Official Symbol
    Cd83provided by MGI
    Official Full Name
    CD83 antigenprovided by MGI
    Primary source
    MGI:MGI:1328316
    See related
    Ensembl:ENSMUSG00000015396 AllianceGenome:MGI:1328316
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Mus musculus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
    Summary
    Acts upstream of or within positive regulation of CD4-positive, alpha-beta T cell differentiation; regulation of cytokine production; and response to organic cyclic compound. Located in external side of plasma membrane. Is expressed in alimentary system; genitourinary system; hemolymphoid system gland; and nervous system. Orthologous to human CD83 (CD83 molecule). [provided by Alliance of Genome Resources, Dec 2024]
    Expression
    Broad expression in spleen adult (RPKM 24.2), thymus adult (RPKM 21.3) and 20 other tissues See more
    Orthologs
    NEW
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    Try the new Transcript table

    Genomic context

    See Cd83 in Genome Data Viewer
    Location:
    13 A4; 13 21.6 cM
    Exon count:
    5
    Annotation release Status Assembly Chr Location
    RS_2024_02 current GRCm39 (GCF_000001635.27) 13 NC_000079.7 (43938661..43956608)
    108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 13 NC_000079.6 (43785112..43803133)

    Chromosome 13 - NC_000079.7Genomic Context describing neighboring genes Neighboring gene predicted gene, 52070 Neighboring gene STARR-seq mESC enhancer starr_34346 Neighboring gene predicted gene, 20751 Neighboring gene STARR-positive B cell enhancer ABC_E10790 Neighboring gene STARR-positive B cell enhancer ABC_E1874 Neighboring gene CapStarr-seq enhancer MGSCv37_chr13:43928236-43928453 Neighboring gene predicted gene, 33115 Neighboring gene predicted gene, 53797 Neighboring gene STARR-positive B cell enhancer ABC_E2405 Neighboring gene CapStarr-seq enhancer MGSCv37_chr13:43960137-43960246 Neighboring gene predicted gene, 33195

    Genomic regions, transcripts, and products

    Expression

    • Project title: Mouse ENCODE transcriptome data
    • Description: RNA profiling data sets generated by the Mouse ENCODE project.
    • BioProject: PRJNA66167
    • Publication: PMID 25409824
    • Analysis date: n/a

    Bibliography

    GeneRIFs: Gene References Into Functions

    What's a GeneRIF?

    Variation

    Alleles

    Alleles of this type are documented at Mouse Genome Informatics  (MGI)

    Pathways from PubChem

    Interactions

    Products Interactant Other Gene Complex Source Pubs Description

    NCBI Reference Sequences (RefSeq)

    NEW Try the new Transcript table

    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001289915.2NP_001276844.1  CD83 antigen isoform 2 precursor

      See identical proteins and their annotated locations for NP_001276844.1

      Status: VALIDATED

      Source sequence(s)
      AC159983
      Conserved Domains (1) summary
      cl11960
      Location:23112
      Ig; Immunoglobulin domain
    2. NM_009856.4NP_033986.1  CD83 antigen isoform 1 precursor

      See identical proteins and their annotated locations for NP_033986.1

      Status: VALIDATED

      Source sequence(s)
      AC159983
      Consensus CDS
      CCDS26481.1
      UniProtKB/Swiss-Prot
      O88324
      UniProtKB/TrEMBL
      Q3T9H6
      Related
      ENSMUSP00000015540.3, ENSMUST00000015540.4
      Conserved Domains (1) summary
      cl11960
      Location:23118
      Ig; Immunoglobulin domain

    RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCm39 C57BL/6J

    Genomic

    1. NC_000079.7 Reference GRCm39 C57BL/6J

      Range
      43938661..43956608
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)