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    Tsx testis specific X-linked gene [ Mus musculus (house mouse) ]

    Gene ID: 22127, updated on 9-Dec-2024

    Summary

    Official Symbol
    Tsxprovided by MGI
    Official Full Name
    testis specific X-linked geneprovided by MGI
    Primary source
    MGI:MGI:108118
    See related
    Ensembl:ENSMUSG00000031329 AllianceGenome:MGI:108118
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Mus musculus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
    Summary
    Acts upstream of or within adult behavior; fertilization; and male gonad development. Located in cytoplasm and male germ cell nucleus. Is expressed in Sertoli cell. [provided by Alliance of Genome Resources, Dec 2024]
    Expression
    Biased expression in testis adult (RPKM 4.8), limb E14.5 (RPKM 0.4) and 5 other tissues See more
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    Genomic context

    See Tsx in Genome Data Viewer
    Location:
    X D; X 46.12 cM
    Exon count:
    9
    Annotation release Status Assembly Chr Location
    RS_2024_02 current GRCm39 (GCF_000001635.27) X NC_000086.8 (102452618..102468194)
    108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) X NC_000086.7 (103409012..103424588)

    Chromosome X - NC_000086.8Genomic Context describing neighboring genes Neighboring gene STARR-seq mESC enhancer starr_47688 Neighboring gene caudal type homeobox 4 Neighboring gene predicted gene 9516 Neighboring gene cysteine-rich hydrophobic domain 1 Neighboring gene STARR-seq mESC enhancer starr_47691 Neighboring gene origin of replication in Tsix Neighboring gene X (inactive)-specific transcript, opposite strand Neighboring gene origin of replication in exon 1 of Xist Neighboring gene inactive X specific transcripts Neighboring gene predicted gene 14861

    Genomic regions, transcripts, and products

    Expression

    • Project title: Mouse ENCODE transcriptome data
    • Description: RNA profiling data sets generated by the Mouse ENCODE project.
    • BioProject: PRJNA66167
    • Publication: PMID 25409824
    • Analysis date: n/a

    Variation

    Alleles

    Alleles of this type are documented at Mouse Genome Informatics  (MGI)

    General gene information

    Markers

    Gene Ontology Provided by MGI

    Function Evidence Code Pubs
    enables molecular_function ND
    No biological Data available
    more info
     
    Process Evidence Code Pubs
    acts_upstream_of_or_within adult behavior IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    acts_upstream_of_or_within fertilization IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    acts_upstream_of_or_within male gonad development IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    Component Evidence Code Pubs
    located_in cytoplasm IDA
    Inferred from Direct Assay
    more info
    PubMed 
    located_in male germ cell nucleus IDA
    Inferred from Direct Assay
    more info
    PubMed 
    located_in nucleus IDA
    Inferred from Direct Assay
    more info
    PubMed 

    General protein information

    Preferred Names
    testis-specific protein TSX
    Names
    testis-specific X-linked protein

    NCBI Reference Sequences (RefSeq)

    NEW Try the new Transcript table

    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001410244.1NP_001397173.1  testis-specific protein TSX

      Status: VALIDATED

      Source sequence(s)
      AL669964
      UniProtKB/Swiss-Prot
      P70675
      UniProtKB/TrEMBL
      F8SHA8, F8SHC2, F8SHC6, F8SHE1, Q78Z65
    2. NM_009440.3NP_033466.1  testis-specific protein TSX

      See identical proteins and their annotated locations for NP_033466.1

      Status: VALIDATED

      Source sequence(s)
      AV265136, BC048493
      Consensus CDS
      CCDS41090.1
      UniProtKB/Swiss-Prot
      P70675
      UniProtKB/TrEMBL
      F8SHA8, F8SHC2, F8SHC6, F8SHE1, Q78Z65
      Related
      ENSMUSP00000033691.5, ENSMUST00000033691.5
      Conserved Domains (1) summary
      pfam17397
      Location:1144
      DUF5404; Family of unknown function (DUF5404)

    RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCm39 C57BL/6J

    Genomic

    1. NC_000086.8 Reference GRCm39 C57BL/6J

      Range
      102452618..102468194
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_006527941.2XP_006528004.1  testis-specific protein TSX isoform X1

      See identical proteins and their annotated locations for XP_006528004.1

      UniProtKB/Swiss-Prot
      P70675
      UniProtKB/TrEMBL
      F8SHA8, F8SHC2, F8SHC6, F8SHE1, Q78Z65
      Conserved Domains (1) summary
      pfam17397
      Location:1144
      DUF5404; Family of unknown function (DUF5404)
    2. XM_006527940.4XP_006528003.1  testis-specific protein TSX isoform X1

      See identical proteins and their annotated locations for XP_006528003.1

      UniProtKB/Swiss-Prot
      P70675
      UniProtKB/TrEMBL
      F8SHA8, F8SHC2, F8SHC6, F8SHE1, Q78Z65
      Conserved Domains (1) summary
      pfam17397
      Location:1144
      DUF5404; Family of unknown function (DUF5404)