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    Or6b1 olfactory receptor family 6 subfamily B member 1 [ Mus musculus (house mouse) ]

    Gene ID: 259067, updated on 27-Nov-2024

    Summary

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    Official Symbol
    Or6b1provided by MGI
    Official Full Name
    olfactory receptor family 6 subfamily B member 1provided by MGI
    Primary source
    MGI:MGI:3030283
    See related
    Ensembl:ENSMUSG00000049168 AllianceGenome:MGI:3030283
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Mus musculus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
    Also known as
    Olfr449; MOR103-1; GA_x6K02T2P3E9-4722003-4721068
    Summary
    Olfactory receptors interact with odorant molecules in the nose, to initiate a neuronal response that triggers the perception of a smell. The olfactory receptor proteins are members of a large family of G-protein-coupled receptors (GPCR) arising from single coding-exon genes. Olfactory receptors share a 7-transmembrane domain structure with many neurotransmitter and hormone receptors and are responsible for the recognition and G protein-mediated transduction of odorant signals. The olfactory receptor gene family is the largest in the genome. [provided by RefSeq, Jul 2008]
    Orthologs
    human all
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    Genomic context

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    See Or6b1 in Genome Data Viewer
    Location:
    6 B2.1; 6 20.93 cM
    Exon count:
    3
    Annotation release Status Assembly Chr Location
    RS_2024_02 current GRCm39 (GCF_000001635.27) 6 NC_000072.7 (42811350..42815816)
    108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 6 NC_000072.6 (42834416..42838882)

    Chromosome 6 - NC_000072.7Genomic Context describing neighboring genes Neighboring gene olfactory receptor family 13 subfamily M member 2, pseudogene 1 Neighboring gene olfactory receptor family 2 subfamily Q member 1 Neighboring gene olfactory receptor enhancer Sfaktiria Neighboring gene olfactory receptor family 2 subfamily A member 5 Neighboring gene olfactory receptor family 2 subfamily A member 25

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Diversity within olfactory sensory derivatives revealed by the contribution of Dbx1 lineages. Causeret F, et al. J Comp Neurol, 2023 Aug. PMID 37125418
    2. Chromosomal location-dependent nonstochastic onset of odor receptor expression. Rodriguez-Gil DJ, et al. J Neurosci, 2010 Jul 28. PMID 20668191, Free PMC Article
    3. The olfactory receptor gene superfamily of the mouse. Zhang X, et al. Nat Neurosci, 2002 Feb. PMID 11802173
    4. Different evolutionary processes shaped the mouse and human olfactory receptor gene families. Young JM, et al. Hum Mol Genet, 2002 Mar 1. PMID 11875048
    5. Odorant receptor expressed sequence tags demonstrate olfactory expression of over 400 genes, extensive alternate splicing and unequal expression levels. Young JM, et al. Genome Biol, 2003. PMID 14611657, Free PMC Article

    See all (8) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Variation

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    Alleles

    Alleles of this type are documented at Mouse Genome Informatics  (MGI)
    • Endonuclease-mediated (1) 

    General gene information

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    Markers

    Homology

    Gene Ontology Provided by MGI

    Function Evidence Code Pubs
    enables olfactory receptor activity IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    enables olfactory receptor activity ISA
    Inferred from Sequence Alignment
    more info
    		 PubMed 
    Process Evidence Code Pubs
    acts_upstream_of_or_within G protein-coupled receptor signaling pathway ISA
    Inferred from Sequence Alignment
    more info
    		 PubMed 
    involved_in detection of chemical stimulus involved in sensory perception of smell IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    acts_upstream_of_or_within sensory perception of smell ISA
    Inferred from Sequence Alignment
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in membrane ISA
    Inferred from Sequence Alignment
    more info
    		 PubMed 
    is_active_in plasma membrane IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  

    General protein information

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    Preferred Names
    olfactory receptor 449
    Names
    olfactory receptor MOR103-1

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001356410.1 → NP_001343339.1  olfactory receptor 449

      Status: VALIDATED

      Source sequence(s)
      AC121317
      Consensus CDS
      CCDS20081.1
      UniProtKB/TrEMBL
      Q8VGW8
      Related
      ENSMUSP00000148895.3, ENSMUST00000214687.3
      Conserved Domains (1) summary
      cd15224
      Location:28 → 292
      7tmA_OR6B-like; olfactory receptor subfamily 6B and related proteins, member of the class A family of seven-transmembrane G protein-coupled receptors

    RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCm39 C57BL/6J

    Genomic

    1. NC_000072.7 Reference GRCm39 C57BL/6J

      Range
      42811350..42815816
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)
    Nucleotide Protein Strain
    Heading Accession and Version

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