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    Hivep1 human immunodeficiency virus type I enhancer binding protein 1 [ Mus musculus (house mouse) ]

    Gene ID: 110521, updated on 27-Nov-2024

    Summary

    Official Symbol
    Hivep1provided by MGI
    Official Full Name
    human immunodeficiency virus type I enhancer binding protein 1provided by MGI
    Primary source
    MGI:MGI:96100
    See related
    Ensembl:ENSMUSG00000021366 AllianceGenome:MGI:96100
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Mus musculus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
    Also known as
    Cryabp1
    Summary
    Enables DNA binding activity and HMG box domain binding activity. Acts upstream of or within negative regulation of DNA-templated transcription. Located in nucleus. Is expressed in several structures, including central nervous system; early conceptus; genitourinary system; hemolymphoid system gland; and musculoskeletal system. Orthologous to human HIVEP1 (HIVEP zinc finger 1). [provided by Alliance of Genome Resources, Nov 2024]
    Expression
    Ubiquitous expression in lung adult (RPKM 7.2), colon adult (RPKM 7.1) and 28 other tissues See more
    Orthologs
    NEW
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    Try the new Transcript table

    Genomic context

    See Hivep1 in Genome Data Viewer
    Location:
    13 A4; 13 20.72 cM
    Exon count:
    13
    Annotation release Status Assembly Chr Location
    RS_2024_02 current GRCm39 (GCF_000001635.27) 13 NC_000079.7 (42205304..42338504)
    108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 13 NC_000079.6 (42051899..42185030)

    Chromosome 13 - NC_000079.7Genomic Context describing neighboring genes Neighboring gene predicted gene, 32555 Neighboring gene STARR-positive B cell enhancer ABC_E925 Neighboring gene STARR-positive B cell enhancer ABC_E5390 Neighboring gene predicted gene 28707 Neighboring gene STARR-positive B cell enhancer mm9_chr13:42189027-42189327 Neighboring gene CapStarr-seq enhancer MGSCv37_chr13:42196875-42197076 Neighboring gene predicted gene, 32778 Neighboring gene STARR-seq mESC enhancer starr_34312 Neighboring gene VISTA enhancer mm235 Neighboring gene STARR-seq mESC enhancer starr_34313 Neighboring gene STARR-seq mESC enhancer starr_34315 Neighboring gene endothelin 1

    Genomic regions, transcripts, and products

    Expression

    • Project title: Mouse ENCODE transcriptome data
    • Description: RNA profiling data sets generated by the Mouse ENCODE project.
    • BioProject: PRJNA66167
    • Publication: PMID 25409824
    • Analysis date: n/a

    Variation

    Alleles

    Alleles of this type are documented at Mouse Genome Informatics  (MGI)
    • Endonuclease-mediated (1) 
    • Targeted (3) 

    Interactions

    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

    Markers

    Gene Ontology Provided by MGI

    Function Evidence Code Pubs
    enables DNA binding IDA
    Inferred from Direct Assay
    more info
    PubMed 
    enables DNA binding ISO
    Inferred from Sequence Orthology
    more info
     
    enables DNA-binding transcription factor activity, RNA polymerase II-specific IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    enables HMG box domain binding IPI
    Inferred from Physical Interaction
    more info
    PubMed 
    enables RNA polymerase II cis-regulatory region sequence-specific DNA binding IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    enables protein binding IPI
    Inferred from Physical Interaction
    more info
    PubMed 
    enables sequence-specific double-stranded DNA binding ISO
    Inferred from Sequence Orthology
    more info
     
    enables zinc ion binding IEA
    Inferred from Electronic Annotation
    more info
     
    Component Evidence Code Pubs
    located_in cytosol ISO
    Inferred from Sequence Orthology
    more info
     
    located_in mitochondrion ISO
    Inferred from Sequence Orthology
    more info
     
    located_in nuclear body ISO
    Inferred from Sequence Orthology
    more info
     
    located_in nucleoplasm ISO
    Inferred from Sequence Orthology
    more info
     
    is_active_in nucleus IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    located_in nucleus IDA
    Inferred from Direct Assay
    more info
    PubMed 
    located_in nucleus ISO
    Inferred from Sequence Orthology
    more info
     

    General protein information

    Preferred Names
    zinc finger protein 40
    Names
    HIV type I enhancer binding protein 1
    alpha A-CRYBP1
    alpha A-crystallin-binding protein 1
    alpha A-crystallin-binding protein I
    alphaA-CRYBP1
    crystallin, alpha binding protein 1
    transcription factor alphaA-CRYBP1

    NCBI Reference Sequences (RefSeq)

    NEW Try the new Transcript table

    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_007772.2NP_031798.2  zinc finger protein 40

      See identical proteins and their annotated locations for NP_031798.2

      Status: VALIDATED

      Source sequence(s)
      AC159258
      Consensus CDS
      CCDS36643.1
      UniProtKB/Swiss-Prot
      Q03172
      UniProtKB/TrEMBL
      F8VPM9
      Related
      ENSMUSP00000056147.6, ENSMUST00000060148.6
      Conserved Domains (5) summary
      sd00017
      Location:409429
      ZF_C2H2; C2H2 Zn finger [structural motif]
      sd00019
      Location:20762096
      ZF_C2H2; C2H2 Zn finger [structural motif]
      pfam00096
      Location:20742096
      zf-C2H2; Zinc finger, C2H2 type
      pfam12756
      Location:21022167
      zf-C2H2_2; C2H2 type zinc-finger (2 copies)
      pfam13465
      Location:422446
      zf-H2C2_2; Zinc-finger double domain

    RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCm39 C57BL/6J

    Genomic

    1. NC_000079.7 Reference GRCm39 C57BL/6J

      Range
      42205304..42338504
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_006516839.5XP_006516902.1  zinc finger protein 40 isoform X1

      See identical proteins and their annotated locations for XP_006516902.1

      UniProtKB/Swiss-Prot
      Q03172
      Conserved Domains (6) summary
      smart00451
      Location:20992130
      ZnF_U1; U1-like zinc finger
      PHA03247
      Location:22982691
      PHA03247; large tegument protein UL36; Provisional
      sd00017
      Location:409429
      ZF_C2H2; C2H2 Zn finger [structural motif]
      sd00019
      Location:20762096
      ZF_C2H2; C2H2 Zn finger [structural motif]
      pfam00096
      Location:20742096
      zf-C2H2; Zinc finger, C2H2 type
      pfam13465
      Location:422446
      zf-H2C2_2; Zinc-finger double domain
    2. XM_006516840.5XP_006516903.1  zinc finger protein 40 isoform X1

      See identical proteins and their annotated locations for XP_006516903.1

      UniProtKB/Swiss-Prot
      Q03172
      Conserved Domains (6) summary
      smart00451
      Location:20992130
      ZnF_U1; U1-like zinc finger
      PHA03247
      Location:22982691
      PHA03247; large tegument protein UL36; Provisional
      sd00017
      Location:409429
      ZF_C2H2; C2H2 Zn finger [structural motif]
      sd00019
      Location:20762096
      ZF_C2H2; C2H2 Zn finger [structural motif]
      pfam00096
      Location:20742096
      zf-C2H2; Zinc finger, C2H2 type
      pfam13465
      Location:422446
      zf-H2C2_2; Zinc-finger double domain
    3. XM_017315358.3XP_017170847.1  zinc finger protein 40 isoform X1

      UniProtKB/Swiss-Prot
      Q03172
      Conserved Domains (6) summary
      smart00451
      Location:20992130
      ZnF_U1; U1-like zinc finger
      PHA03247
      Location:22982691
      PHA03247; large tegument protein UL36; Provisional
      sd00017
      Location:409429
      ZF_C2H2; C2H2 Zn finger [structural motif]
      sd00019
      Location:20762096
      ZF_C2H2; C2H2 Zn finger [structural motif]
      pfam00096
      Location:20742096
      zf-C2H2; Zinc finger, C2H2 type
      pfam13465
      Location:422446
      zf-H2C2_2; Zinc-finger double domain
    4. XM_030247127.2XP_030102987.1  zinc finger protein 40 isoform X2

      UniProtKB/Swiss-Prot
      Q03172
      Conserved Domains (6) summary
      smart00451
      Location:19822013
      ZnF_U1; U1-like zinc finger
      PHA03247
      Location:21812574
      PHA03247; large tegument protein UL36; Provisional
      sd00017
      Location:292312
      ZF_C2H2; C2H2 Zn finger [structural motif]
      sd00019
      Location:19591979
      ZF_C2H2; C2H2 Zn finger [structural motif]
      pfam00096
      Location:19571979
      zf-C2H2; Zinc finger, C2H2 type
      pfam13465
      Location:305329
      zf-H2C2_2; Zinc-finger double domain