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    Bpifa6 BPI fold containing family A, member 6 [ Mus musculus (house mouse) ]

    Gene ID: 545477, updated on 27-Nov-2024

    Summary

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    Official Symbol
    Bpifa6provided by MGI
    Official Full Name
    BPI fold containing family A, member 6provided by MGI
    Primary source
    MGI:MGI:3647736
    See related
    Ensembl:ENSMUSG00000078998 AllianceGenome:MGI:3647736
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Mus musculus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
    Also known as
    Gm5840; Splunc6; EG545477
    Expression
    Restricted expression toward testis adult (RPKM 3.6) See more
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    Genomic context

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    See Bpifa6 in Genome Data Viewer
    Location:
    2 H1; 2 76.06 cM
    Exon count:
    11
    Annotation release Status Assembly Chr Location
    RS_2024_02 current GRCm39 (GCF_000001635.27) 2 NC_000068.8 (153816865..153842415)
    108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 2 NC_000068.7 (153974945..154000495)

    Chromosome 2 - NC_000068.8Genomic Context describing neighboring genes Neighboring gene BPI fold containing family B, member 3 Neighboring gene BPI fold containing family B, member 4 Neighboring gene BPI fold containing family A, member 2 Neighboring gene Friend virus susceptibility protein 1-like

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Expression

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    • Project title: Mouse ENCODE transcriptome data
    • Description: RNA profiling data sets generated by the Mouse ENCODE project.
    • BioProject: PRJNA66167
    • Publication: PMID 25409824
    • Analysis date: n/a

    Bibliography

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    Related articles in PubMed

    1. Comparative analysis of the PLUNC (palate, lung and nasal epithelium clone) protein families. Bingle CD, et al. Biochem Soc Trans, 2003 Aug. PMID 12887310
    2. Expansion of the Bactericidal/Permeability Increasing-like (BPI-like) protein locus in cattle. Wheeler TT, et al. BMC Genomics, 2007 Mar 15. PMID 17362520, Free PMC Article
    3. Systematic nomenclature for the PLUNC/PSP/BSP30/SMGB proteins as a subfamily of the BPI fold-containing superfamily. Bingle CD, et al. Biochem Soc Trans, 2011 Aug. PMID 21787333, Free PMC Article
    4. A conditional knockout resource for the genome-wide study of mouse gene function. Skarnes WC, et al. Nature, 2011 Jun 15. PMID 21677750, Free PMC Article
    5. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. Strausberg RL, et al. Proc Natl Acad Sci U S A, 2002 Dec 24. PMID 12477932, Free PMC Article

    GeneRIFs: Gene References Into Functions

    Variation

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    Alleles

    Alleles of this type are documented at Mouse Genome Informatics  (MGI)
    • Endonuclease-mediated (1) 

    General gene information

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    Homology

    Clone Names

    • MGC105160

    Gene Ontology Provided by MGI

    Function Evidence Code Pubs
    enables molecular_function ND
    No biological Data available
    more info
    		  
    Process Evidence Code Pubs
    involved_in biological_process ND
    No biological Data available
    more info
    		  
    Component Evidence Code Pubs
    is_active_in cellular_component ND
    No biological Data available
    more info
    		  

    General protein information

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    Preferred Names
    Splunc6; splunc6

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001080811.1 → NP_001074280.1  Splunc6 precursor

      See identical proteins and their annotated locations for NP_001074280.1

      Status: PROVISIONAL

      Source sequence(s)
      BC082608
      Consensus CDS
      CCDS50760.1
      UniProtKB/TrEMBL
      Q0VGU8
      Related
      ENSMUSP00000105375.3, ENSMUST00000109753.3
      Conserved Domains (1) summary
      cl00188
      Location:204 → 349
      BPI; BPI/LBP/CETP domain; Bactericidal permeability-increasing protein (BPI) / Lipopolysaccharide-binding protein (LBP) / Cholesteryl ester transfer protein (CETP) domain; binds to and neutralizes lipopolysaccharides from the outer membrane of Gram-negative ...

    RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCm39 C57BL/6J

    Genomic

    1. NC_000068.8 Reference GRCm39 C57BL/6J

      Range
      153816865..153842415
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_011239702.1 → XP_011238004.1  splunc6 isoform X1

      Conserved Domains (1) summary
      cl00188
      Location:96 → 241
      BPI; BPI/LBP/CETP domain; Bactericidal permeability-increasing protein (BPI) / Lipopolysaccharide-binding protein (LBP) / Cholesteryl ester transfer protein (CETP) domain; binds to and neutralizes lipopolysaccharides from the outer membrane of Gram-negative ...
    Nucleotide Protein Strain
    Heading Accession and Version

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