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    Abca14 ATP-binding cassette, sub-family A member 14 [ Mus musculus (house mouse) ]

    Gene ID: 67928, updated on 9-Dec-2024

    Summary

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    Official Symbol
    Abca14provided by MGI
    Official Full Name
    ATP-binding cassette, sub-family A member 14provided by MGI
    Primary source
    MGI:MGI:2388708
    See related
    Ensembl:ENSMUSG00000062017 AllianceGenome:MGI:2388708
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Mus musculus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
    Also known as
    1700110B15Rik; 4930539G24Rik
    Summary
    Predicted to enable ATPase-coupled transmembrane transporter activity and lipid transporter activity. Predicted to be involved in lipid transport. Predicted to be active in intracellular membrane-bounded organelle. Is expressed in testis. [provided by Alliance of Genome Resources, Dec 2024]
    Expression
    Restricted expression toward testis adult (RPKM 8.7) See more
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    Genomic context

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    See Abca14 in Genome Data Viewer
    Location:
    7 F2; 7 64.5 cM
    Exon count:
    34
    Annotation release Status Assembly Chr Location
    RS_2024_02 current GRCm39 (GCF_000001635.27) 7 NC_000073.7 (119803150..119924577)
    108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 7 NC_000073.6 (120203927..120325354)

    Chromosome 7 - NC_000073.7Genomic Context describing neighboring genes Neighboring gene ankyrin repeat and sterile alpha motif domain containing 4B Neighboring gene crystallin, mu Neighboring gene STARR-seq mESC enhancer starr_20044 Neighboring gene STARR-seq mESC enhancer starr_20045 Neighboring gene STARR-seq mESC enhancer starr_20046 Neighboring gene ATP-binding cassette, sub-family A member 15 Neighboring gene STARR-seq mESC enhancer starr_20047 Neighboring gene ATP-binding cassette, sub-family A member 16 Neighboring gene STARR-seq mESC enhancer starr_20049 Neighboring gene SEC14 and spectrin domains 1 pseudogene

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Expression

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    • Project title: Mouse ENCODE transcriptome data
    • Description: RNA profiling data sets generated by the Mouse ENCODE project.
    • BioProject: PRJNA66167
    • Publication: PMID 25409824
    • Analysis date: n/a

    Bibliography

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    Related articles in PubMed

    1. Three ATP-binding cassette transporter genes, Abca14, Abca15, and Abca16, form a cluster on mouse Chromosome 7F3. Chen ZQ, et al. Mamm Genome, 2004 May. PMID 15170222
    2. High-throughput discovery of novel developmental phenotypes. Dickinson ME, et al. Nature, 2016 Sep 22. PMID 27626380, Free PMC Article
    3. Genetic determinants of micronucleus formation in vivo. Adams DJ, et al. Nature, 2024 Mar. PMID 38355793, Free PMC Article
    4. Antisense transcription in the mammalian transcriptome. Katayama S, et al. Science, 2005 Sep 2. PMID 16141073
    5. High-efficiency full-length cDNA cloning. Carninci P, et al. Methods Enzymol, 1999. PMID 10349636

    See all (12) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Variation

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    Alleles

    Alleles of this type are documented at Mouse Genome Informatics  (MGI)
    • Targeted (2) 

    General gene information

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    Markers

    Homology

    Gene Ontology Provided by MGI

    Function Evidence Code Pubs
    enables ATPase-coupled transmembrane transporter activity IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    enables lipid transporter activity IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    Process Evidence Code Pubs
    involved_in lipid transport IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    Component Evidence Code Pubs
    is_active_in intracellular membrane-bounded organelle IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  

    General protein information

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    Preferred Names
    ATP-binding cassette, sub-family A (ABC1), member 14
    Names
    ATP-binding cassette transporter sub-family A member 14

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_026458.4 → NP_080734.3  ATP-binding cassette, sub-family A (ABC1), member 14

      See identical proteins and their annotated locations for NP_080734.3

      Status: VALIDATED

      Source sequence(s)
      AC126434, AC151052
      Consensus CDS
      CCDS40108.1
      UniProtKB/TrEMBL
      E9Q8F8, Q6XBG3
      Related
      ENSMUSP00000081690.3, ENSMUST00000084640.3
      Conserved Domains (1) summary
      TIGR01257
      Location:128 → 1673
      rim_protein; retinal-specific rim ABC transporter

    RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCm39 C57BL/6J

    Genomic

    1. NC_000073.7 Reference GRCm39 C57BL/6J

      Range
      119803150..119924577
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_017312271.2 → XP_017167760.1  ATP-binding cassette, sub-family A (ABC1), member 14 isoform X1

      UniProtKB/TrEMBL
      Q6XBG3
      Conserved Domains (1) summary
      TIGR01257
      Location:128 → 1709
      rim_protein; retinal-specific rim ABC transporter

    2. XM_017312273.2 → XP_017167762.1  ATP-binding cassette, sub-family A (ABC1), member 14 isoform X3

      Conserved Domains (1) summary
      TIGR01257
      Location:128 → 942
      rim_protein; retinal-specific rim ABC transporter

    3. XM_017312274.2 → XP_017167763.1  ATP-binding cassette, sub-family A (ABC1), member 14 isoform X4

      UniProtKB/TrEMBL
      Q8BIR8
      Conserved Domains (1) summary
      TIGR01257
      Location:128 → 896
      rim_protein; retinal-specific rim ABC transporter

    4. XM_006508142.3 → XP_006508205.1  ATP-binding cassette, sub-family A (ABC1), member 14 isoform X2

      See identical proteins and their annotated locations for XP_006508205.1

      UniProtKB/TrEMBL
      E9Q8F8, Q6XBG3
      Conserved Domains (1) summary
      TIGR01257
      Location:128 → 1673
      rim_protein; retinal-specific rim ABC transporter

    5. XM_006508143.3 → XP_006508206.1  ATP-binding cassette, sub-family A (ABC1), member 14 isoform X2

      See identical proteins and their annotated locations for XP_006508206.1

      UniProtKB/TrEMBL
      E9Q8F8, Q6XBG3
      Conserved Domains (1) summary
      TIGR01257
      Location:128 → 1673
      rim_protein; retinal-specific rim ABC transporter

    RNA

    1. XR_003946550.1 RNA Sequence

    Nucleotide Protein Strain
    Heading Accession and Version

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