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    Tmub1 transmembrane and ubiquitin-like domain containing 1 [ Mus musculus (house mouse) ]

    Gene ID: 64295, updated on 9-Dec-2024

    Summary

    Official Symbol
    Tmub1provided by MGI
    Official Full Name
    transmembrane and ubiquitin-like domain containing 1provided by MGI
    Primary source
    MGI:MGI:1923764
    See related
    Ensembl:ENSMUSG00000028958 AllianceGenome:MGI:1923764
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Mus musculus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
    Also known as
    Hops; 2010004O20Rik
    Summary
    Predicted to be involved in ERAD pathway. Predicted to be located in several cellular components, including centrosome; postsynaptic membrane; and recycling endosome. Orthologous to human TMUB1 (transmembrane and ubiquitin like domain containing 1). [provided by Alliance of Genome Resources, Dec 2024]
    Expression
    Ubiquitous expression in duodenum adult (RPKM 41.2), colon adult (RPKM 38.0) and 27 other tissues See more
    Orthologs
    NEW
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    Try the new Transcript table

    Genomic context

    See Tmub1 in Genome Data Viewer
    Location:
    5 A3; 5 11.79 cM
    Exon count:
    3
    Annotation release Status Assembly Chr Location
    RS_2024_02 current GRCm39 (GCF_000001635.27) 5 NC_000071.7 (24650461..24652859, complement)
    108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 5 NC_000071.6 (24445463..24447846, complement)

    Chromosome 5 - NC_000071.7Genomic Context describing neighboring genes Neighboring gene solute carrier family 4 (anion exchanger), member 2 Neighboring gene predicted gene, 22333 Neighboring gene Fas-activated serine/threonine kinase Neighboring gene ArfGAP with GTPase domain, ankyrin repeat and PH domain 3 Neighboring gene VISTA enhancer mm1191 Neighboring gene gastrulation brain homeobox 1

    Genomic regions, transcripts, and products

    Expression

    • Project title: Mouse ENCODE transcriptome data
    • Description: RNA profiling data sets generated by the Mouse ENCODE project.
    • BioProject: PRJNA66167
    • Publication: PMID 25409824
    • Analysis date: n/a

    Bibliography

    GeneRIFs: Gene References Into Functions

    What's a GeneRIF?

    Variation

    Alleles

    Alleles of this type are documented at Mouse Genome Informatics  (MGI)
    • Endonuclease-mediated (2) 
    • Targeted (2)  1 citation

    Interactions

    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

    Markers

    Gene Ontology Provided by MGI

    Process Evidence Code Pubs
    involved_in ERAD pathway IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    involved_in ERAD pathway IEA
    Inferred from Electronic Annotation
    more info
     
    involved_in ERAD pathway ISO
    Inferred from Sequence Orthology
    more info
     
    Component Evidence Code Pubs
    located_in centrosome IEA
    Inferred from Electronic Annotation
    more info
     
    located_in nucleolus IEA
    Inferred from Electronic Annotation
    more info
     
    located_in postsynaptic membrane IEA
    Inferred from Electronic Annotation
    more info
     
    located_in recycling endosome IEA
    Inferred from Electronic Annotation
    more info
     

    General protein information

    Preferred Names
    transmembrane and ubiquitin-like domain-containing protein 1
    Names
    hepatocyte odd protein shuttling protein

    NCBI Reference Sequences (RefSeq)

    NEW Try the new Transcript table

    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_022418.3NP_071863.1  transmembrane and ubiquitin-like domain-containing protein 1

      See identical proteins and their annotated locations for NP_071863.1

      Status: VALIDATED

      Source sequence(s)
      AB030183, BB871344
      Consensus CDS
      CCDS19121.1
      UniProtKB/Swiss-Prot
      Q53AQ3, Q9JMG3
      UniProtKB/TrEMBL
      E9QN77
      Related
      ENSMUSP00000030799.9, ENSMUST00000030799.15
      Conserved Domains (1) summary
      cd17131
      Location:101171
      Ubl_TMUB1; ubiquitin-like (Ubl) domain found in transmembrane and ubiquitin-like domain-containing protein 1 (TMUB1)

    RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCm39 C57BL/6J

    Genomic

    1. NC_000071.7 Reference GRCm39 C57BL/6J

      Range
      24650461..24652859 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_006535786.3XP_006535849.1  transmembrane and ubiquitin-like domain-containing protein 1 isoform X1

      See identical proteins and their annotated locations for XP_006535849.1

      UniProtKB/Swiss-Prot
      Q53AQ3, Q9JMG3
      UniProtKB/TrEMBL
      E9QN77
      Conserved Domains (1) summary
      cd17131
      Location:101171
      Ubl_TMUB1; ubiquitin-like (Ubl) domain found in transmembrane and ubiquitin-like domain-containing protein 1 (TMUB1)