Sprr2a3 small proline-rich protein 2A3 [Mus musculus (house mouse)] - Gene

Summary

Official Symbol: Sprr2a3provided by MGI
Official Full Name: small proline-rich protein 2A3provided by MGI
Primary source: MGI:MGI:3845028
See related: Ensembl:ENSMUSG00000074445 AllianceGenome:MGI:3845028
Gene type: protein coding
RefSeq status: VALIDATED
Organism: Mus musculus
Lineage: Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
Also known as: Sprr2a; Sprr2a1
Summary: Predicted to enable lipid binding activity. Involved in defense response to Gram-positive bacterium. Is active in extracellular region and secretory granule. Is expressed in stomach and thymus primordium. [provided by Alliance of Genome Resources, Jan 2025]
Expression: Biased expression in stomach adult (RPKM 7615.5), small intestine adult (RPKM 5309.9) and 4 other tissues See more
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Genomic context

Location:: 3 F1; 3 40.14 cM

Exon count:: 2

Annotation release	Status	Assembly	Chr	Location
RS_2024_02	current	GRCm39 (GCF_000001635.27)	3	NC_000069.7 (92192611..92196571)
108.20200622	previous assembly	GRCm38.p6 (GCF_000001635.26)	3	NC_000069.6 (92285304..92289264)

Chromosome 3 - NC_000069.7 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Genomic Sequence:

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Expression

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See details

Project title: Mouse ENCODE transcriptome data
Description: RNA profiling data sets generated by the Mouse ENCODE project.
BioProject: PRJNA66167
Publication: PMID 25409824
Analysis date: n/a

Bibliography

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GeneRIFs: Gene References Into Functions

What's a GeneRIF?

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General gene information

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Gene Ontology Provided by MGI

Function	Evidence Code	Pubs
enables lipid binding	ISS Inferred from Sequence or Structural Similarity more info
enables molecular_function	ND No biological Data available more info

Process	Evidence Code	Pubs
involved_in defense response to Gram-positive bacterium	IDA Inferred from Direct Assay more info	PubMed

Component	Evidence Code	Pubs
located_in cornified envelope	IEA Inferred from Electronic Annotation more info
is_active_in extracellular region	IDA Inferred from Direct Assay more info	PubMed
is_active_in secretory granule	IDA Inferred from Direct Assay more info	PubMed
located_in transport vesicle	IEA Inferred from Electronic Annotation more info

General protein information

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Preferred Names: small proline-rich protein 2A3

Names: Small proline-rich protein 2A1; small proline-rich protein 2A

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.