Dcaf12l2 DDB1 and CUL4 associated factor 12-like 2 [Mus musculus (house mouse)] - Gene

Summary

Official Symbol: Dcaf12l2provided by MGI
Official Full Name: DDB1 and CUL4 associated factor 12-like 2provided by MGI
Primary source: MGI:MGI:2445178
See related: Ensembl:ENSMUSG00000050926 AllianceGenome:MGI:2445178
Gene type: protein coding
RefSeq status: VALIDATED
Organism: Mus musculus
Lineage: Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
Also known as: Wdr40c; A130007F10Rik
Summary: Predicted to be part of Cul4-RING E3 ubiquitin ligase complex. Orthologous to human DCAF12L2 (DDB1 and CUL4 associated factor 12 like 2). [provided by Alliance of Genome Resources, Nov 2024]
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Genomic context

Location:: X A4; X 23.85 cM

Exon count:: 1

Annotation release	Status	Assembly	Chr	Location
RS_2024_02	current	GRCm39 (GCF_000001635.27)	X	NC_000086.8 (43454334..43457214, complement)
108.20200622	previous assembly	GRCm38.p6 (GCF_000001635.26)	X	NC_000086.7 (44365457..44368337, complement)

Chromosome X - NC_000086.8 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Genomic Sequence:

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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GeneRIFs: Gene References Into Functions

What's a GeneRIF?

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Variation

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Alleles

Alleles of this type are documented at Mouse Genome Informatics (MGI)

Endonuclease-mediated (2)

General gene information

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Gene Ontology Provided by MGI

Function	Evidence Code	Pubs
enables molecular_function	ND No biological Data available more info

Process	Evidence Code	Pubs
involved_in biological_process	ND No biological Data available more info

Component	Evidence Code	Pubs
part_of Cul4-RING E3 ubiquitin ligase complex	IBA Inferred from Biological aspect of Ancestor more info

General protein information

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Preferred Names: DDB1- and CUL4-associated factor 12-like protein 2

Names: WD repeat domain 40C; WD repeat-containing protein 40C; WD40 domain

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

NM_175539.3 → NP_780748.1 DDB1- and CUL4-associated factor 12-like protein 2

See identical proteins and their annotated locations for NP_780748.1

Status: VALIDATED

Source sequence(s)

AK037333, AL670220

Consensus CDS

CCDS30100.1

UniProtKB/Swiss-Prot

Q8BGW4

Related

ENSMUSP00000110709.2, ENSMUST00000115057.2

Conserved Domains (3) summary

COG2319
Location:117 → 423

WD40; WD40 repeat [General function prediction only]

sd00039
Location:158 → 197

7WD40; WD40 repeat [structural motif]

cl02567
Location:95 → 295

WD40; WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly; typically contains a GH dipeptide 11-24 residues from ...