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    Lsmem2 leucine-rich single-pass membrane protein 2 [ Mus musculus (house mouse) ]

    Gene ID: 434436, updated on 9-Dec-2024

    Summary

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    Official Symbol
    Lsmem2provided by MGI
    Official Full Name
    leucine-rich single-pass membrane protein 2provided by MGI
    Primary source
    MGI:MGI:3612240
    See related
    Ensembl:ENSMUSG00000103409 AllianceGenome:MGI:3612240
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Mus musculus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
    Summary
    Orthologous to human LSMEM2 (leucine rich single-pass membrane protein 2). [provided by Alliance of Genome Resources, Dec 2024]
    Expression
    Biased expression in heart adult (RPKM 16.0), mammary gland adult (RPKM 4.1) and 11 other tissues See more
    Orthologs
    human all
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    Genomic context

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    See Lsmem2 in Genome Data Viewer
    Location:
    9 F1; 9 58.28 cM
    Exon count:
    6
    Annotation release Status Assembly Chr Location
    RS_2024_02 current GRCm39 (GCF_000001635.27) 9 NC_000075.7 (107469825..107475189, complement)
    108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 9 NC_000075.6 (107592626..107597990, complement)

    Chromosome 9 - NC_000075.7Genomic Context describing neighboring genes Neighboring gene STARR-positive B cell enhancer ABC_E2304 Neighboring gene STARR-seq mESC enhancer starr_25176 Neighboring gene hyaluronoglucosaminidase 2 Neighboring gene hyaluronoglucosaminidase 1 Neighboring gene STARR-positive B cell enhancer ABC_E300 Neighboring gene N(alpha)-acetyltransferase 80, NatH catalytic subunit Neighboring gene hyaluronoglucosaminidase 3 Neighboring gene interferon-related developmental regulator 2 Neighboring gene STARR-positive B cell enhancer ABC_E11753 Neighboring gene sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3B Neighboring gene STARR-positive B cell enhancer ABC_E8314 Neighboring gene G protein subunit alpha i2 Neighboring gene CapStarr-seq enhancer MGSCv37_chr9:107527067-107527220 Neighboring gene STARR-seq mESC enhancer starr_25181 Neighboring gene predicted gene, 53518 Neighboring gene STARR-seq mESC enhancer starr_25182 Neighboring gene STARR-positive B cell enhancer ABC_E5103 Neighboring gene CapStarr-seq enhancer MGSCv37_chr9:107546963-107547072 Neighboring gene STARR-positive B cell enhancer ABC_E8315 Neighboring gene solute carrier family 38, member 3

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Expression

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    • Project title: Mouse ENCODE transcriptome data
    • Description: RNA profiling data sets generated by the Mouse ENCODE project.
    • BioProject: PRJNA66167
    • Publication: PMID 25409824
    • Analysis date: n/a

    Bibliography

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    Related articles in PubMed

    1. A conditional knockout resource for the genome-wide study of mouse gene function. Skarnes WC, et al. Nature, 2011 Jun 15. PMID 21677750, Free PMC Article
    2. Analysis of the mouse transcriptome based on functional annotation of 60,770 full-length cDNAs. Okazaki Y, et al. Nature, 2002 Dec 5. PMID 12466851

    GeneRIFs: Gene References Into Functions

    General gene information

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    Markers

    Homology

    Gene Ontology Provided by MGI

    Function Evidence Code Pubs
    enables molecular_function ND
    No biological Data available
    more info
    		  
    Process Evidence Code Pubs
    involved_in biological_process ND
    No biological Data available
    more info
    		  
    Component Evidence Code Pubs
    is_active_in cellular_component ND
    No biological Data available
    more info
    		  

    General protein information

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    Preferred Names
    leucine-rich single-pass membrane protein 2

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001370877.1 → NP_001357806.1  leucine-rich single-pass membrane protein 2

      Status: VALIDATED

      Source sequence(s)
      AL672219
      Consensus CDS
      CCDS90659.1
      UniProtKB/TrEMBL
      A0A571BE98
      Related
      ENSMUSP00000158647.2, ENSMUST00000238519.2
      Conserved Domains (1) summary
      pfam15833
      Location:1 → 148
      DUF4714; Domain of unknown function (DUF4714)

    RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCm39 C57BL/6J

    Genomic

    1. NC_000075.7 Reference GRCm39 C57BL/6J

      Range
      107469825..107475189 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_030244443.1 → XP_030100303.1  leucine-rich single-pass membrane protein 2 isoform X2

      Related
      ENSMUST00000191791.3
      Conserved Domains (1) summary
      pfam15833
      Location:10 → 151
      DUF4714; Domain of unknown function (DUF4714)

    2. XM_030244442.1 → XP_030100302.1  leucine-rich single-pass membrane protein 2 isoform X1

      Conserved Domains (1) summary
      pfam15833
      Location:16 → 162
      DUF4714; Domain of unknown function (DUF4714)

    Suppressed Reference Sequence(s)

    The following Reference Sequences have been suppressed. Explain

    1. NM_001081244.1: Suppressed sequence

      Description
      NM_001081244.1: This RefSeq was permanently suppressed because currently there is insufficient support for the transcript and the protein.
    Nucleotide Protein Strain
    Heading Accession and Version

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