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    Mical3 microtubule associated monooxygenase, calponin and LIM domain containing 3 [ Mus musculus (house mouse) ]

    Gene ID: 194401, updated on 27-Nov-2024

    Summary

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    Official Symbol
    Mical3provided by MGI
    Official Full Name
    microtubule associated monooxygenase, calponin and LIM domain containing 3provided by MGI
    Primary source
    MGI:MGI:2442733
    See related
    Ensembl:ENSMUSG00000051586 AllianceGenome:MGI:2442733
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Mus musculus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
    Also known as
    Mical-3; mKIAA1364; C130040D16Rik
    Summary
    Predicted to enable several functions, including FAD binding activity; actin binding activity; and oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NAD(P)H as one donor, and incorporation of one atom of oxygen. Predicted to be involved in actin filament depolymerization. Predicted to be located in several cellular components, including Flemming body; intercellular bridge; and nucleoplasm. Is expressed in several structures, including axial skeleton; central nervous system; hindlimb interdigital region mesenchyme; sensory organ; and vibrissa. Orthologous to human MICAL3 (microtubule associated monooxygenase, calponin and LIM domain containing 3). [provided by Alliance of Genome Resources, Nov 2024]
    Expression
    Ubiquitous expression in testis adult (RPKM 14.5), ovary adult (RPKM 11.3) and 28 other tissues See more
    Orthologs
    human all
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    Genomic context

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    See Mical3 in Genome Data Viewer
    Location:
    6 F1; 6 57.03 cM
    Exon count:
    48
    Annotation release Status Assembly Chr Location
    RS_2024_02 current GRCm39 (GCF_000001635.27) 6 NC_000072.7 (120908507..121150716, complement)
    108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 6 NC_000072.6 (120931546..121173757, complement)

    Chromosome 6 - NC_000072.7Genomic Context describing neighboring genes Neighboring gene STARR-positive B cell enhancer ABC_E6479 Neighboring gene BCL2 like 13 Neighboring gene STARR-seq mESC enhancer starr_17194 Neighboring gene STARR-positive B cell enhancer ABC_E8126 Neighboring gene STARR-positive B cell enhancer ABC_E10407 Neighboring gene CapStarr-seq enhancer MGSCv37_chr6:120880485-120880722 Neighboring gene ATPase, H+ transporting, lysosomal V1 subunit G1 pseudogene Neighboring gene CapStarr-seq enhancer MGSCv37_chr6:120884294-120884494 Neighboring gene CapStarr-seq enhancer MGSCv37_chr6:120885601-120885784 Neighboring gene BH3 interacting domain death agonist Neighboring gene STARR-positive B cell enhancer ABC_E6480 Neighboring gene CapStarr-seq enhancer MGSCv37_chr6:120907410-120907630 Neighboring gene STARR-positive B cell enhancer ABC_E11335 Neighboring gene predicted gene, 43915 Neighboring gene STARR-positive B cell enhancer ABC_E6481 Neighboring gene STARR-seq mESC enhancer starr_17203 Neighboring gene VISTA enhancer mm580 Neighboring gene predicted gene 4651 Neighboring gene STARR-positive B cell enhancer ABC_E439 Neighboring gene predicted gene, 57772 Neighboring gene STARR-positive B cell enhancer ABC_E3676 Neighboring gene multiple inositol polyphosphate histidine phosphatase 1, pseudogene Neighboring gene predicted gene, 30842 Neighboring gene peroxisomal biogenesis factor 26 Neighboring gene predicted gene, 38651

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Expression

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    • Project title: Mouse ENCODE transcriptome data
    • Description: RNA profiling data sets generated by the Mouse ENCODE project.
    • BioProject: PRJNA66167
    • Publication: PMID 25409824
    • Analysis date: n/a

    Bibliography

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    Related articles in PubMed

    1. Identification of novel Ack1-interacting proteins and Ack1 phosphorylated sites in mouse brain by mass spectrometry. Del Mar Masdeu M, et al. Oncotarget, 2017 Nov 24. PMID 29254152, Free PMC Article
    2. Impaired OTUD7A-dependent Ankyrin regulation mediates neuronal dysfunction in mouse and human models of the 15q13.3 microdeletion syndrome. Unda BK, et al. Mol Psychiatry, 2023 Apr. PMID 36604605, Free PMC Article
    3. Qualitative and quantitative analyses of protein phosphorylation in naive and stimulated mouse synaptosomal preparations. Munton RP, et al. Mol Cell Proteomics, 2007 Feb. PMID 17114649
    4. Prediction of the coding sequences of mouse homologues of KIAA gene: II. The complete nucleotide sequences of 400 mouse KIAA-homologous cDNAs identified by screening of terminal sequences of cDNA clones randomly sampled from size-fractionated libraries. Okazaki N, et al. DNA Res, 2003 Feb 28. PMID 12693553
    5. Prediction of the coding sequences of mouse homologues of KIAA gene: IV. The complete nucleotide sequences of 500 mouse KIAA-homologous cDNAs identified by screening of terminal sequences of cDNA clones randomly sampled from size-fractionated libraries. Okazaki N, et al. DNA Res, 2004 Jun 30. PMID 15368895

    See all (25) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Variation

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    Alleles

    Alleles of this type are documented at Mouse Genome Informatics  (MGI)
    • Endonuclease-mediated (1) 

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Markers

    Homology

    Clone Names

    • KIAA0819

    Gene Ontology Provided by MGI

    Function Evidence Code Pubs
    enables F-actin monooxygenase activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables FAD binding ISS
    Inferred from Sequence or Structural Similarity
    more info
    		  
    enables actin binding ISO
    Inferred from Sequence Orthology
    more info
    		  
    enables actin binding ISS
    Inferred from Sequence or Structural Similarity
    more info
    		  
    enables metal ion binding IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables molecular adaptor activity ISO
    Inferred from Sequence Orthology
    more info
    		  
    enables oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NAD(P)H as one donor, and incorporation of one atom of oxygen ISS
    Inferred from Sequence or Structural Similarity
    more info
    		  
    Process Evidence Code Pubs
    involved_in actin filament depolymerization ISO
    Inferred from Sequence Orthology
    more info
    		  
    involved_in actin filament depolymerization ISS
    Inferred from Sequence or Structural Similarity
    more info
    		  
    involved_in cell division IEA
    Inferred from Electronic Annotation
    more info
    		  
    involved_in cytoskeleton organization ISO
    Inferred from Sequence Orthology
    more info
    		  
    involved_in cytoskeleton organization ISS
    Inferred from Sequence or Structural Similarity
    more info
    		  
    involved_in exocytosis IEA
    Inferred from Electronic Annotation
    more info
    		  
    Component Evidence Code Pubs
    located_in Flemming body ISO
    Inferred from Sequence Orthology
    more info
    		  
    located_in cell cortex IEA
    Inferred from Electronic Annotation
    more info
    		  
    located_in cell projection IEA
    Inferred from Electronic Annotation
    more info
    		  
    located_in cytosol ISO
    Inferred from Sequence Orthology
    more info
    		  
    located_in intercellular bridge ISO
    Inferred from Sequence Orthology
    more info
    		  
    located_in midbody IEA
    Inferred from Electronic Annotation
    more info
    		  
    located_in nucleoplasm ISO
    Inferred from Sequence Orthology
    more info
    		  
    located_in nucleus ISO
    Inferred from Sequence Orthology
    more info
    		  
    located_in nucleus ISS
    Inferred from Sequence or Structural Similarity
    more info
    		  
    located_in plasma membrane ISO
    Inferred from Sequence Orthology
    more info
    		  
    located_in spindle IEA
    Inferred from Electronic Annotation
    more info
    		  

    General protein information

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    Preferred Names
    [F-actin]-monooxygenase MICAL3; F-actin-monooxygenase MICAL3
    Names
    [F-actin]-methionine sulfoxide oxidase MICAL3
    flavoprotein oxidoreductase MICAL3
    molecule interacting with CasL protein 3
    protein-methionine sulfoxide oxidase MICAL3
    NP_001257404.1
    NP_700445.2
    XP_006505863.1
    XP_030111106.1
    XP_030111107.1
    XP_030111108.1
    XP_030111109.1
    XP_030111110.1
    XP_030111111.1
    XP_030111112.1
    XP_030111113.1
    XP_030111114.1
    XP_030111115.1
    XP_030111117.1
    XP_030111118.1
    XP_030111119.1
    XP_030111120.1
    XP_030111121.1
    XP_030111122.1
    XP_030111123.1
    XP_030111124.1
    XP_030111125.1
    XP_030111127.1
    XP_030111128.1
    XP_030111129.1
    XP_030111130.1
    XP_036021853.1
    XP_036021854.1
    XP_036021855.1
    XP_036021856.1
    XP_036021857.1

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001270475.1 → NP_001257404.1  [F-actin]-monooxygenase MICAL3 isoform 1

      See identical proteins and their annotated locations for NP_001257404.1

      Status: VALIDATED

      Description
      Transcript Variant: This variant (1) represents the longest transcript and encodes the longer isoform (1).
      Source sequence(s)
      AI845760, AK035932, AK048201, AK147803, BC043122, BC090651, BM899307, CJ105256
      Consensus CDS
      CCDS85152.1
      UniProtKB/Swiss-Prot
      B2RR77, Q3UGQ8, Q3V160, Q69ZY5, Q80TE8, Q8BXB1, Q8CJ19
      UniProtKB/TrEMBL
      A0A5F8MPN4
      Conserved Domains (7) summary
      cd09439
      Location:764 → 818
      LIM_Mical; The LIM domain of Mical (molecule interacting with CasL)
      PHA03307
      Location:1077 → 1506
      PHA03307; transcriptional regulator ICP4; Provisional
      COG2072
      Location:85 → 219
      CzcO; Predicted flavoprotein CzcO associated with the cation diffusion facilitator CzcD [Inorganic ion transport and metabolism]
      pfam04094
      Location:1483 → 1976
      DUF390; Protein of unknown function (DUF390)
      pfam00307
      Location:524 → 625
      CH; Calponin homology (CH) domain
      pfam01494
      Location:87 → 141
      FAD_binding_3; FAD binding domain
      pfam12130
      Location:1845 → 1979
      DUF3585; Protein of unknown function (DUF3585)

    2. NM_153396.3 → NP_700445.2  [F-actin]-monooxygenase MICAL3 isoform 2

      See identical proteins and their annotated locations for NP_700445.2

      Status: VALIDATED

      Description
      Transcript Variant: This variant (2) differs in the 5' UTR, lacks several 3' exons and includes an alternate 3' exon. The encoded isoform (2) has a distinct and shorter C-terminus compared to isoform 1.
      Source sequence(s)
      AC079443, AC153584, AK132669, BX630380
      Consensus CDS
      CCDS20487.1
      UniProtKB/Swiss-Prot
      Q8CJ19
      Related
      ENSMUSP00000076402.6, ENSMUST00000077159.8
      Conserved Domains (3) summary
      pfam01494
      Location:87 → 274
      FAD_binding_3; FAD binding domain
      cd21251
      Location:515 → 625
      CH_MICAL3; calponin homology (CH) domain found in molecule interacting with CasL protein 3
      cl02475
      Location:764 → 809
      LIM; LIM is a small protein-protein interaction domain, containing two zinc fingers

    RNA

    1. NR_138097.1 RNA Sequence

      Status: VALIDATED

      Source sequence(s)
      AC079443, AC153584, AK132669
      Related
      ENSMUST00000203254.3

    RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCm39 C57BL/6J

    Genomic

    1. NC_000072.7 Reference GRCm39 C57BL/6J

      Range
      120908507..121150716 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_030255261.2 → XP_030111121.1  F-actin-monooxygenase MICAL3 isoform X16

      UniProtKB/TrEMBL
      A0A5F8MPN4
      Conserved Domains (6) summary
      cd09439
      Location:764 → 818
      LIM_Mical; The LIM domain of Mical (molecule interacting with CasL)
      PHA03307
      Location:1076 → 1505
      PHA03307; transcriptional regulator ICP4; Provisional
      COG2072
      Location:85 → 219
      CzcO; Predicted flavoprotein CzcO associated with the cation diffusion facilitator CzcD [Inorganic ion transport and metabolism]
      pfam00307
      Location:524 → 625
      CH; Calponin homology (CH) domain
      pfam01494
      Location:87 → 141
      FAD_binding_3; FAD binding domain
      pfam12130
      Location:1861 → 2034
      DUF3585; Protein of unknown function (DUF3585)

    2. XM_030255258.2 → XP_030111118.1  F-actin-monooxygenase MICAL3 isoform X12

      UniProtKB/TrEMBL
      A0A5F8MPU7
      Conserved Domains (6) summary
      cd09439
      Location:764 → 818
      LIM_Mical; The LIM domain of Mical (molecule interacting with CasL)
      PHA03307
      Location:1128 → 1557
      PHA03307; transcriptional regulator ICP4; Provisional
      COG2072
      Location:85 → 219
      CzcO; Predicted flavoprotein CzcO associated with the cation diffusion facilitator CzcD [Inorganic ion transport and metabolism]
      pfam00307
      Location:524 → 625
      CH; Calponin homology (CH) domain
      pfam01494
      Location:87 → 141
      FAD_binding_3; FAD binding domain
      pfam12130
      Location:1913 → 2086
      DUF3585; Protein of unknown function (DUF3585)

    3. XM_036165960.1 → XP_036021853.1  F-actin-monooxygenase MICAL3 isoform X1

      UniProtKB/TrEMBL
      A0A5F8MPU7
      Conserved Domains (5) summary
      cd09439
      Location:916 → 970
      LIM_Mical; The LIM domain of Mical (molecule interacting with CasL)
      PHA03307
      Location:1280 → 1709
      PHA03307; transcriptional regulator ICP4; Provisional
      pfam01494
      Location:87 → 274
      FAD_binding_3; FAD binding domain
      pfam12130
      Location:2065 → 2233
      DUF3585; Protein of unknown function (DUF3585)
      cd21251
      Location:515 → 625
      CH_MICAL3; calponin homology (CH) domain found in molecule interacting with CasL protein 3

    4. XM_030255267.2 → XP_030111127.1  F-actin-monooxygenase MICAL3 isoform X21

      UniProtKB/TrEMBL
      A0A5F8MPF3
      Conserved Domains (5) summary
      cd09439
      Location:764 → 818
      LIM_Mical; The LIM domain of Mical (molecule interacting with CasL)
      PHA03307
      Location:1031 → 1460
      PHA03307; transcriptional regulator ICP4; Provisional
      pfam01494
      Location:87 → 274
      FAD_binding_3; FAD binding domain
      pfam12130
      Location:1799 → 1967
      DUF3585; Protein of unknown function (DUF3585)
      cd21251
      Location:515 → 625
      CH_MICAL3; calponin homology (CH) domain found in molecule interacting with CasL protein 3

    5. XM_030255246.2 → XP_030111106.1  F-actin-monooxygenase MICAL3 isoform X2

      UniProtKB/TrEMBL
      A0A5F8MPU7
      Conserved Domains (6) summary
      cd09439
      Location:916 → 970
      LIM_Mical; The LIM domain of Mical (molecule interacting with CasL)
      PHA03307
      Location:1280 → 1709
      PHA03307; transcriptional regulator ICP4; Provisional
      COG2072
      Location:85 → 219
      CzcO; Predicted flavoprotein CzcO associated with the cation diffusion facilitator CzcD [Inorganic ion transport and metabolism]
      pfam00307
      Location:524 → 625
      CH; Calponin homology (CH) domain
      pfam01494
      Location:87 → 141
      FAD_binding_3; FAD binding domain
      pfam12130
      Location:2065 → 2221
      DUF3585; Protein of unknown function (DUF3585)

    6. XM_030255249.2 → XP_030111109.1  F-actin-monooxygenase MICAL3 isoform X5

      UniProtKB/TrEMBL
      A0A5F8MPU7
      Conserved Domains (6) summary
      cd09439
      Location:880 → 934
      LIM_Mical; The LIM domain of Mical (molecule interacting with CasL)
      PHA03307
      Location:1244 → 1673
      PHA03307; transcriptional regulator ICP4; Provisional
      COG2072
      Location:85 → 219
      CzcO; Predicted flavoprotein CzcO associated with the cation diffusion facilitator CzcD [Inorganic ion transport and metabolism]
      pfam00307
      Location:524 → 625
      CH; Calponin homology (CH) domain
      pfam01494
      Location:87 → 141
      FAD_binding_3; FAD binding domain
      pfam12130
      Location:2029 → 2202
      DUF3585; Protein of unknown function (DUF3585)

    7. XM_030255248.2 → XP_030111108.1  F-actin-monooxygenase MICAL3 isoform X4

      UniProtKB/TrEMBL
      A0A5F8MPU7
      Conserved Domains (6) summary
      cd09439
      Location:916 → 970
      LIM_Mical; The LIM domain of Mical (molecule interacting with CasL)
      PHA03307
      Location:1280 → 1709
      PHA03307; transcriptional regulator ICP4; Provisional
      COG2072
      Location:85 → 219
      CzcO; Predicted flavoprotein CzcO associated with the cation diffusion facilitator CzcD [Inorganic ion transport and metabolism]
      pfam00307
      Location:524 → 625
      CH; Calponin homology (CH) domain
      pfam01494
      Location:87 → 141
      FAD_binding_3; FAD binding domain
      pfam12130
      Location:2048 → 2204
      DUF3585; Protein of unknown function (DUF3585)

    8. XM_030255247.2 → XP_030111107.1  F-actin-monooxygenase MICAL3 isoform X3

      UniProtKB/TrEMBL
      A0A5F8MPU7
      Conserved Domains (6) summary
      cd09439
      Location:916 → 970
      LIM_Mical; The LIM domain of Mical (molecule interacting with CasL)
      PHA03307
      Location:1280 → 1709
      PHA03307; transcriptional regulator ICP4; Provisional
      COG2072
      Location:85 → 219
      CzcO; Predicted flavoprotein CzcO associated with the cation diffusion facilitator CzcD [Inorganic ion transport and metabolism]
      pfam00307
      Location:524 → 625
      CH; Calponin homology (CH) domain
      pfam01494
      Location:87 → 141
      FAD_binding_3; FAD binding domain
      pfam12130
      Location:2065 → 2216
      DUF3585; Protein of unknown function (DUF3585)

    9. XM_030255251.2 → XP_030111111.1  F-actin-monooxygenase MICAL3 isoform X7

      UniProtKB/TrEMBL
      A0A5F8MPU7
      Conserved Domains (6) summary
      cd09439
      Location:916 → 970
      LIM_Mical; The LIM domain of Mical (molecule interacting with CasL)
      PHA03307
      Location:1280 → 1709
      PHA03307; transcriptional regulator ICP4; Provisional
      COG2072
      Location:85 → 219
      CzcO; Predicted flavoprotein CzcO associated with the cation diffusion facilitator CzcD [Inorganic ion transport and metabolism]
      pfam00307
      Location:524 → 625
      CH; Calponin homology (CH) domain
      pfam01494
      Location:87 → 141
      FAD_binding_3; FAD binding domain
      pfam12130
      Location:2048 → 2199
      DUF3585; Protein of unknown function (DUF3585)

    10. XM_030255250.2 → XP_030111110.1  F-actin-monooxygenase MICAL3 isoform X6

      UniProtKB/TrEMBL
      A0A5F8MPU7
      Conserved Domains (6) summary
      cd09439
      Location:916 → 970
      LIM_Mical; The LIM domain of Mical (molecule interacting with CasL)
      PHA03307
      Location:1280 → 1709
      PHA03307; transcriptional regulator ICP4; Provisional
      COG2072
      Location:85 → 219
      CzcO; Predicted flavoprotein CzcO associated with the cation diffusion facilitator CzcD [Inorganic ion transport and metabolism]
      pfam00307
      Location:524 → 625
      CH; Calponin homology (CH) domain
      pfam01494
      Location:87 → 141
      FAD_binding_3; FAD binding domain
      pfam12130
      Location:2065 → 2199
      DUF3585; Protein of unknown function (DUF3585)

    11. XM_030255254.2 → XP_030111114.1  F-actin-monooxygenase MICAL3 isoform X10

      UniProtKB/TrEMBL
      A0A5F8MPU7
      Conserved Domains (6) summary
      cd09439
      Location:792 → 846
      LIM_Mical; The LIM domain of Mical (molecule interacting with CasL)
      PHA03307
      Location:1156 → 1585
      PHA03307; transcriptional regulator ICP4; Provisional
      COG2072
      Location:85 → 219
      CzcO; Predicted flavoprotein CzcO associated with the cation diffusion facilitator CzcD [Inorganic ion transport and metabolism]
      pfam00307
      Location:524 → 625
      CH; Calponin homology (CH) domain
      pfam01494
      Location:87 → 141
      FAD_binding_3; FAD binding domain
      pfam12130
      Location:1941 → 2114
      DUF3585; Protein of unknown function (DUF3585)

    12. XM_036165961.1 → XP_036021854.1  F-actin-monooxygenase MICAL3 isoform X13

      UniProtKB/TrEMBL
      A0A5F8MPU7
      Conserved Domains (5) summary
      cd09439
      Location:764 → 818
      LIM_Mical; The LIM domain of Mical (molecule interacting with CasL)
      PHA03307
      Location:1127 → 1556
      PHA03307; transcriptional regulator ICP4; Provisional
      pfam01494
      Location:87 → 274
      FAD_binding_3; FAD binding domain
      pfam12130
      Location:1912 → 2080
      DUF3585; Protein of unknown function (DUF3585)
      cd21251
      Location:515 → 625
      CH_MICAL3; calponin homology (CH) domain found in molecule interacting with CasL protein 3

    13. XM_030255257.2 → XP_030111117.1  F-actin-monooxygenase MICAL3 isoform X12

      UniProtKB/TrEMBL
      A0A5F8MPU7
      Conserved Domains (6) summary
      cd09439
      Location:764 → 818
      LIM_Mical; The LIM domain of Mical (molecule interacting with CasL)
      PHA03307
      Location:1128 → 1557
      PHA03307; transcriptional regulator ICP4; Provisional
      COG2072
      Location:85 → 219
      CzcO; Predicted flavoprotein CzcO associated with the cation diffusion facilitator CzcD [Inorganic ion transport and metabolism]
      pfam00307
      Location:524 → 625
      CH; Calponin homology (CH) domain
      pfam01494
      Location:87 → 141
      FAD_binding_3; FAD binding domain
      pfam12130
      Location:1913 → 2086
      DUF3585; Protein of unknown function (DUF3585)

    14. XM_030255262.2 → XP_030111122.1  F-actin-monooxygenase MICAL3 isoform X17

      UniProtKB/TrEMBL
      A0A5F8MPF3
      Conserved Domains (6) summary
      cd09439
      Location:792 → 846
      LIM_Mical; The LIM domain of Mical (molecule interacting with CasL)
      PHA03307
      Location:1059 → 1488
      PHA03307; transcriptional regulator ICP4; Provisional
      COG2072
      Location:85 → 219
      CzcO; Predicted flavoprotein CzcO associated with the cation diffusion facilitator CzcD [Inorganic ion transport and metabolism]
      pfam00307
      Location:524 → 625
      CH; Calponin homology (CH) domain
      pfam01494
      Location:87 → 141
      FAD_binding_3; FAD binding domain
      pfam12130
      Location:1844 → 2017
      DUF3585; Protein of unknown function (DUF3585)

    15. XM_030255264.2 → XP_030111124.1  F-actin-monooxygenase MICAL3 isoform X19

      UniProtKB/TrEMBL
      A0A5F8MPF3
      Conserved Domains (6) summary
      cd09439
      Location:764 → 818
      LIM_Mical; The LIM domain of Mical (molecule interacting with CasL)
      PHA03307
      Location:1030 → 1459
      PHA03307; transcriptional regulator ICP4; Provisional
      COG2072
      Location:85 → 219
      CzcO; Predicted flavoprotein CzcO associated with the cation diffusion facilitator CzcD [Inorganic ion transport and metabolism]
      pfam00307
      Location:524 → 625
      CH; Calponin homology (CH) domain
      pfam01494
      Location:87 → 141
      FAD_binding_3; FAD binding domain
      pfam12130
      Location:1815 → 1988
      DUF3585; Protein of unknown function (DUF3585)

    16. XM_030255260.2 → XP_030111120.1  F-actin-monooxygenase MICAL3 isoform X15

      UniProtKB/TrEMBL
      A0A5F8MPN4
      Conserved Domains (6) summary
      cd09439
      Location:764 → 818
      LIM_Mical; The LIM domain of Mical (molecule interacting with CasL)
      PHA03307
      Location:1077 → 1506
      PHA03307; transcriptional regulator ICP4; Provisional
      COG2072
      Location:85 → 219
      CzcO; Predicted flavoprotein CzcO associated with the cation diffusion facilitator CzcD [Inorganic ion transport and metabolism]
      pfam00307
      Location:524 → 625
      CH; Calponin homology (CH) domain
      pfam01494
      Location:87 → 141
      FAD_binding_3; FAD binding domain
      pfam12130
      Location:1862 → 2035
      DUF3585; Protein of unknown function (DUF3585)

    17. XM_030255263.2 → XP_030111123.1  F-actin-monooxygenase MICAL3 isoform X18

      UniProtKB/TrEMBL
      A0A5F8MPF3
      Conserved Domains (6) summary
      cd09439
      Location:764 → 818
      LIM_Mical; The LIM domain of Mical (molecule interacting with CasL)
      PHA03307
      Location:1031 → 1460
      PHA03307; transcriptional regulator ICP4; Provisional
      COG2072
      Location:85 → 219
      CzcO; Predicted flavoprotein CzcO associated with the cation diffusion facilitator CzcD [Inorganic ion transport and metabolism]
      pfam00307
      Location:524 → 625
      CH; Calponin homology (CH) domain
      pfam01494
      Location:87 → 141
      FAD_binding_3; FAD binding domain
      pfam12130
      Location:1816 → 1989
      DUF3585; Protein of unknown function (DUF3585)

    18. XM_036165962.1 → XP_036021855.1  F-actin-monooxygenase MICAL3 isoform X21

      UniProtKB/TrEMBL
      A0A5F8MPF3
      Conserved Domains (5) summary
      cd09439
      Location:764 → 818
      LIM_Mical; The LIM domain of Mical (molecule interacting with CasL)
      PHA03307
      Location:1031 → 1460
      PHA03307; transcriptional regulator ICP4; Provisional
      pfam01494
      Location:87 → 274
      FAD_binding_3; FAD binding domain
      pfam12130
      Location:1799 → 1967
      DUF3585; Protein of unknown function (DUF3585)
      cd21251
      Location:515 → 625
      CH_MICAL3; calponin homology (CH) domain found in molecule interacting with CasL protein 3

    19. XM_006505800.2 → XP_006505863.1  F-actin-monooxygenase MICAL3 isoform X20

      See identical proteins and their annotated locations for XP_006505863.1

      UniProtKB/Swiss-Prot
      B2RR77, Q3UGQ8, Q3V160, Q69ZY5, Q80TE8, Q8BXB1, Q8CJ19
      UniProtKB/TrEMBL
      A0A5F8MPN4
      Conserved Domains (7) summary
      cd09439
      Location:764 → 818
      LIM_Mical; The LIM domain of Mical (molecule interacting with CasL)
      PHA03307
      Location:1077 → 1506
      PHA03307; transcriptional regulator ICP4; Provisional
      COG2072
      Location:85 → 219
      CzcO; Predicted flavoprotein CzcO associated with the cation diffusion facilitator CzcD [Inorganic ion transport and metabolism]
      pfam04094
      Location:1483 → 1976
      DUF390; Protein of unknown function (DUF390)
      pfam00307
      Location:524 → 625
      CH; Calponin homology (CH) domain
      pfam01494
      Location:87 → 141
      FAD_binding_3; FAD binding domain
      pfam12130
      Location:1845 → 1979
      DUF3585; Protein of unknown function (DUF3585)

    20. XM_030255253.2 → XP_030111113.1  F-actin-monooxygenase MICAL3 isoform X9

      UniProtKB/TrEMBL
      A0A5F8MPN4
      Conserved Domains (6) summary
      cd09439
      Location:916 → 970
      LIM_Mical; The LIM domain of Mical (molecule interacting with CasL)
      PHA03307
      Location:1229 → 1658
      PHA03307; transcriptional regulator ICP4; Provisional
      COG2072
      Location:85 → 219
      CzcO; Predicted flavoprotein CzcO associated with the cation diffusion facilitator CzcD [Inorganic ion transport and metabolism]
      pfam00307
      Location:524 → 625
      CH; Calponin homology (CH) domain
      pfam01494
      Location:87 → 141
      FAD_binding_3; FAD binding domain
      pfam12130
      Location:1997 → 2131
      DUF3585; Protein of unknown function (DUF3585)

    21. XM_030255265.2 → XP_030111125.1  F-actin-monooxygenase MICAL3 isoform X20

      UniProtKB/Swiss-Prot
      B2RR77, Q3UGQ8, Q3V160, Q69ZY5, Q80TE8, Q8BXB1, Q8CJ19
      UniProtKB/TrEMBL
      A0A5F8MPN4
      Related
      ENSMUSP00000146544.2, ENSMUST00000207889.2
      Conserved Domains (7) summary
      cd09439
      Location:764 → 818
      LIM_Mical; The LIM domain of Mical (molecule interacting with CasL)
      PHA03307
      Location:1077 → 1506
      PHA03307; transcriptional regulator ICP4; Provisional
      COG2072
      Location:85 → 219
      CzcO; Predicted flavoprotein CzcO associated with the cation diffusion facilitator CzcD [Inorganic ion transport and metabolism]
      pfam04094
      Location:1483 → 1976
      DUF390; Protein of unknown function (DUF390)
      pfam00307
      Location:524 → 625
      CH; Calponin homology (CH) domain
      pfam01494
      Location:87 → 141
      FAD_binding_3; FAD binding domain
      pfam12130
      Location:1845 → 1979
      DUF3585; Protein of unknown function (DUF3585)

    22. XM_030255252.2 → XP_030111112.1  F-actin-monooxygenase MICAL3 isoform X8

      UniProtKB/TrEMBL
      A0A5F8MPU7
      Conserved Domains (6) summary
      cd09439
      Location:916 → 970
      LIM_Mical; The LIM domain of Mical (molecule interacting with CasL)
      PHA03307
      Location:1280 → 1709
      PHA03307; transcriptional regulator ICP4; Provisional
      COG2072
      Location:85 → 219
      CzcO; Predicted flavoprotein CzcO associated with the cation diffusion facilitator CzcD [Inorganic ion transport and metabolism]
      pfam00307
      Location:524 → 625
      CH; Calponin homology (CH) domain
      pfam01494
      Location:87 → 141
      FAD_binding_3; FAD binding domain
      pfam12130
      Location:2048 → 2182
      DUF3585; Protein of unknown function (DUF3585)

    23. XM_036165963.1 → XP_036021856.1  F-actin-monooxygenase MICAL3 isoform X22

      UniProtKB/TrEMBL
      A0A5F8MPF3
      Related
      ENSMUSP00000158944.2, ENSMUST00000238957.2
      Conserved Domains (5) summary
      cd09439
      Location:764 → 818
      LIM_Mical; The LIM domain of Mical (molecule interacting with CasL)
      PHA03307
      Location:1031 → 1460
      PHA03307; transcriptional regulator ICP4; Provisional
      pfam01494
      Location:87 → 274
      FAD_binding_3; FAD binding domain
      pfam12130
      Location:1799 → 1928
      DUF3585; Protein of unknown function (DUF3585)
      cd21251
      Location:515 → 625
      CH_MICAL3; calponin homology (CH) domain found in molecule interacting with CasL protein 3

    24. XM_030255255.2 → XP_030111115.1  F-actin-monooxygenase MICAL3 isoform X11

      UniProtKB/TrEMBL
      A0A5F8MPU7
      Conserved Domains (6) summary
      cd09439
      Location:916 → 970
      LIM_Mical; The LIM domain of Mical (molecule interacting with CasL)
      PHA03307
      Location:1280 → 1709
      PHA03307; transcriptional regulator ICP4; Provisional
      COG2072
      Location:85 → 219
      CzcO; Predicted flavoprotein CzcO associated with the cation diffusion facilitator CzcD [Inorganic ion transport and metabolism]
      pfam00307
      Location:524 → 625
      CH; Calponin homology (CH) domain
      pfam01494
      Location:87 → 141
      FAD_binding_3; FAD binding domain
      cl23748
      Location:2065 → 2094
      DUF3585; Protein of unknown function (DUF3585)

    25. XM_030255259.2 → XP_030111119.1  F-actin-monooxygenase MICAL3 isoform X14

      UniProtKB/TrEMBL
      A0A5F8MPU7
      Conserved Domains (6) summary
      cd09439
      Location:916 → 970
      LIM_Mical; The LIM domain of Mical (molecule interacting with CasL)
      PHA03307
      Location:1280 → 1709
      PHA03307; transcriptional regulator ICP4; Provisional
      COG2072
      Location:85 → 219
      CzcO; Predicted flavoprotein CzcO associated with the cation diffusion facilitator CzcD [Inorganic ion transport and metabolism]
      pfam00307
      Location:524 → 625
      CH; Calponin homology (CH) domain
      pfam01494
      Location:87 → 141
      FAD_binding_3; FAD binding domain
      cl23748
      Location:2048 → 2077
      DUF3585; Protein of unknown function (DUF3585)

    26. XM_030255268.2 → XP_030111128.1  F-actin-monooxygenase MICAL3 isoform X23

      Conserved Domains (4) summary
      COG2072
      Location:85 → 219
      CzcO; Predicted flavoprotein CzcO associated with the cation diffusion facilitator CzcD [Inorganic ion transport and metabolism]
      cl02475
      Location:916 → 961
      LIM; LIM is a small protein-protein interaction domain, containing two zinc fingers
      pfam00307
      Location:524 → 625
      CH; Calponin homology (CH) domain
      pfam01494
      Location:87 → 141
      FAD_binding_3; FAD binding domain

    27. XM_030255269.2 → XP_030111129.1  F-actin-monooxygenase MICAL3 isoform X24

      Conserved Domains (4) summary
      COG2072
      Location:85 → 219
      CzcO; Predicted flavoprotein CzcO associated with the cation diffusion facilitator CzcD [Inorganic ion transport and metabolism]
      cl02475
      Location:792 → 837
      LIM; LIM is a small protein-protein interaction domain, containing two zinc fingers
      pfam00307
      Location:524 → 625
      CH; Calponin homology (CH) domain
      pfam01494
      Location:87 → 141
      FAD_binding_3; FAD binding domain

    28. XM_030255270.2 → XP_030111130.1  F-actin-monooxygenase MICAL3 isoform X25

      Conserved Domains (3) summary
      pfam01494
      Location:87 → 274
      FAD_binding_3; FAD binding domain
      cd21251
      Location:515 → 625
      CH_MICAL3; calponin homology (CH) domain found in molecule interacting with CasL protein 3
      cl02475
      Location:764 → 809
      LIM; LIM is a small protein-protein interaction domain, containing two zinc fingers

    29. XM_036165964.1 → XP_036021857.1  F-actin-monooxygenase MICAL3 isoform X25

      Conserved Domains (3) summary
      pfam01494
      Location:87 → 274
      FAD_binding_3; FAD binding domain
      cd21251
      Location:515 → 625
      CH_MICAL3; calponin homology (CH) domain found in molecule interacting with CasL protein 3
      cl02475
      Location:764 → 809
      LIM; LIM is a small protein-protein interaction domain, containing two zinc fingers
    Nucleotide Protein Strain
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q8CJ19.2 GenPept UniProtKB/Swiss-Prot:Q8CJ19

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