Mrfap1 Morf4 family associated protein 1 [Mus musculus (house mouse)] - Gene

Summary

Official Symbol: Mrfap1provided by MGI
Official Full Name: Morf4 family associated protein 1provided by MGI
Primary source: MGI:MGI:1914818
See related: Ensembl:ENSMUSG00000055302 AllianceGenome:MGI:1914818
Gene type: protein coding
RefSeq status: VALIDATED
Organism: Mus musculus
Lineage: Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
Also known as: Pam14; 9130413I22Rik
Summary: Predicted to enable identical protein binding activity. Predicted to be located in nucleoplasm. Is expressed in brain; genitourinary system; liver; lung; and spleen. Orthologous to several human genes including MRFAP1 (Morf4 family associated protein 1). [provided by Alliance of Genome Resources, Dec 2024]
Expression: Ubiquitous expression in placenta adult (RPKM 151.4), CNS E11.5 (RPKM 141.2) and 28 other tissues See more
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Genomic context

Location:: 5 B3; 5 19.26 cM

Exon count:: 2

Annotation release	Status	Assembly	Chr	Location
RS_2024_02	current	GRCm39 (GCF_000001635.27)	5	NC_000071.7 (36952211..36954098, complement)
108.20200622	previous assembly	GRCm38.p6 (GCF_000001635.26)	5	NC_000071.6 (36794867..36796754, complement)

Chromosome 5 - NC_000071.7 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Genomic Sequence:

Go to nucleotide: Graphics FASTA GenBank

Expression

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See details

Project title: Mouse ENCODE transcriptome data
Description: RNA profiling data sets generated by the Mouse ENCODE project.
BioProject: PRJNA66167
Publication: PMID 25409824
Analysis date: n/a

Bibliography

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GeneRIFs: Gene References Into Functions

What's a GeneRIF?

Not essential for normal mouse development and cell cycle control, likely acts as an adaptor protein in nucleoprotein complexes.
Title: PAM14, a novel MRG- and Rb-associated protein, is not required for development and T-cell function in mice.

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Variation

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Alleles

Alleles of this type are documented at Mouse Genome Informatics (MGI)

Targeted (1) 1 citation

Interactions

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Products	Interactant	Other Gene	Complex	Source	Pubs	Description

General gene information

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Markers

RH126619 (e-PCR)
- UniSTS:209721

RH125359 (e-PCR)
- UniSTS:162181

Gene Ontology Provided by MGI

Function	Evidence Code	Pubs
enables identical protein binding	ISO Inferred from Sequence Orthology more info
enables protein binding	IPI Inferred from Physical Interaction more info	PubMed

Process	Evidence Code	Pubs
involved_in biological_process	ND No biological Data available more info

Component	Evidence Code	Pubs
located_in nucleoplasm	ISO Inferred from Sequence Orthology more info
located_in nucleus	IEA Inferred from Electronic Annotation more info
located_in perinuclear region of cytoplasm	IEA Inferred from Electronic Annotation more info

General protein information

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Preferred Names: MORF4 family-associated protein 1

Names: protein associated with MRG of 14 kDa; protein associated with MRG, 14 kDa

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.