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    Sft2d1 SFT2 domain containing 1 [ Mus musculus (house mouse) ]

    Gene ID: 106489, updated on 9-Dec-2024

    Summary

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    Official Symbol
    Sft2d1provided by MGI
    Official Full Name
    SFT2 domain containing 1provided by MGI
    Primary source
    MGI:MGI:1918689
    See related
    Ensembl:ENSMUSG00000073468 AllianceGenome:MGI:1918689
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Mus musculus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
    Also known as
    5630401J11Rik
    Summary
    Predicted to be involved in protein transport and vesicle-mediated transport. Predicted to be located in several cellular components, including cytoplasm; endomembrane system; and intracellular membrane-bounded organelle. Orthologous to human SFT2D1 (SFT2 domain containing 1). [provided by Alliance of Genome Resources, Dec 2024]
    Expression
    Ubiquitous expression in duodenum adult (RPKM 38.0), CNS E18 (RPKM 33.8) and 28 other tissues See more
    Orthologs
    human all
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    Genomic context

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    See Sft2d1 in Genome Data Viewer
    Location:
    17 A1; 17 4.92 cM
    Exon count:
    9
    Annotation release Status Assembly Chr Location
    RS_2024_02 current GRCm39 (GCF_000001635.27) 17 NC_000083.7 (8529920..8546274)
    108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 17 NC_000083.6 (8311088..8327442)

    Chromosome 17 - NC_000083.7Genomic Context describing neighboring genes Neighboring gene predicted gene, 33799 Neighboring gene predicted gene 8465 Neighboring gene STARR-positive B cell enhancer ABC_E1188 Neighboring gene RIKEN cDNA 4930506C21 gene Neighboring gene mitochondrial pyruvate carrier 1 Neighboring gene CapStarr-seq enhancer MGSCv37_chr17:8503785-8503968 Neighboring gene proline rich 18 Neighboring gene predicted gene, 46592 Neighboring gene protein FAM32A pseudogene Neighboring gene brachyury 2

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Expression

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    • Project title: Mouse ENCODE transcriptome data
    • Description: RNA profiling data sets generated by the Mouse ENCODE project.
    • BioProject: PRJNA66167
    • Publication: PMID 25409824
    • Analysis date: n/a

    Bibliography

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    Related articles in PubMed

    1. A comparison of whole-genome shotgun-derived mouse chromosome 16 and the human genome. Mural RJ, et al. Science, 2002 May 31. PMID 12040188
    2. A large-scale, gene-driven mutagenesis approach for the functional analysis of the mouse genome. Hansen J, et al. Proc Natl Acad Sci U S A, 2003 Aug 19. PMID 12904583, Free PMC Article
    3. Genome-wide expression profiling of mid-gestation placenta and embryo using a 15,000 mouse developmental cDNA microarray. Tanaka TS, et al. Proc Natl Acad Sci U S A, 2000 Aug 1. PMID 10922068, Free PMC Article
    4. Normalization and subtraction: two approaches to facilitate gene discovery. Bonaldo MF, et al. Genome Res, 1996 Sep. PMID 8889548
    5. Wnk1 kinase deficiency lowers blood pressure in mice: a gene-trap screen to identify potential targets for therapeutic intervention. Zambrowicz BP, et al. Proc Natl Acad Sci U S A, 2003 Nov 25. PMID 14610273, Free PMC Article

    See all (15) citations in PubMed

    GeneRIFs: Gene References Into Functions

    General gene information

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    Markers

    Homology

    Clone Names

    • MGC102361

    Gene Ontology Provided by MGI

    Function Evidence Code Pubs
    enables molecular_function ND
    No biological Data available
    more info
    		  
    Process Evidence Code Pubs
    involved_in protein transport IEA
    Inferred from Electronic Annotation
    more info
    		  
    involved_in vesicle-mediated transport IEA
    Inferred from Electronic Annotation
    more info
    		  
    Component Evidence Code Pubs
    located_in cytoplasm IEA
    Inferred from Electronic Annotation
    more info
    		  
    located_in endomembrane system IEA
    Inferred from Electronic Annotation
    more info
    		  
    located_in intracellular membrane-bounded organelle IEA
    Inferred from Electronic Annotation
    more info
    		  
    located_in membrane IEA
    Inferred from Electronic Annotation
    more info
    		  

    General protein information

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    Preferred Names
    vesicle transport protein SFT2A
    Names
    SFT2 domain-containing protein 1

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001357890.1 → NP_001344819.1  vesicle transport protein SFT2A isoform 2

      Status: VALIDATED

      Source sequence(s)
      AC164431, AW049769
      Conserved Domains (1) summary
      pfam04178
      Location:1 → 95
      Got1; Got1/Sft2-like family

    2. NM_134114.2 → NP_598875.2  vesicle transport protein SFT2A isoform 1

      See identical proteins and their annotated locations for NP_598875.2

      Status: VALIDATED

      Source sequence(s)
      AK151338, CAAA01222630
      Consensus CDS
      CCDS49945.1
      UniProtKB/Swiss-Prot
      A1L3Q4, Q5SSN7
      Related
      ENSMUSP00000117294.2, ENSMUST00000154553.2
      Conserved Domains (1) summary
      pfam04178
      Location:38 → 155
      Got1; Got1/Sft2-like family

    RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCm39 C57BL/6J

    Genomic

    1. NC_000083.7 Reference GRCm39 C57BL/6J

      Range
      8529920..8546274
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_011246185.4 → XP_011244487.1  vesicle transport protein SFT2A isoform X1

      See identical proteins and their annotated locations for XP_011244487.1

      Conserved Domains (1) summary
      pfam04178
      Location:1 → 95
      Got1; Got1/Sft2-like family
    Nucleotide Protein Strain
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q5SSN7.1 GenPept UniProtKB/Swiss-Prot:Q5SSN7

    Gene LinkOut

    The following LinkOut resources are supplied by external providers. These providers are responsible for maintaining the links.

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