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    PTPN13 protein tyrosine phosphatase non-receptor type 13 [ Homo sapiens (human) ]

    Gene ID: 5783, updated on 10-Dec-2024

    Summary

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    Official Symbol
    PTPN13provided by HGNC
    Official Full Name
    protein tyrosine phosphatase non-receptor type 13provided by HGNC
    Primary source
    HGNC:HGNC:9646
    See related
    Ensembl:ENSG00000163629 MIM:600267; AllianceGenome:HGNC:9646
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Homo sapiens
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
    Also known as
    PNP1; FAP-1; PTP1E; PTPL1; PTPLE; PTP-BL; hPTP1E; PTP-BAS
    Summary
    The protein encoded by this gene is a member of the protein tyrosine phosphatase (PTP) family. PTPs are signaling molecules that regulate a variety of cellular processes including cell growth, differentiation, mitotic cycle, and oncogenic transformation. This PTP is a large intracellular protein. It has a catalytic PTP domain at its C-terminus and two major structural domains: a region with five PDZ domains and a FERM domain that binds to plasma membrane and cytoskeletal elements. This PTP was found to interact with, and dephosphorylate, Fas receptor and IkappaBalpha through the PDZ domains. This suggests it has a role in Fas mediated programmed cell death. This PTP was also shown to interact with GTPase-activating protein, and thus may function as a regulator of Rho signaling pathways. Four alternatively spliced transcript variants, which encode distinct proteins, have been reported. [provided by RefSeq, Oct 2008]
    Expression
    Broad expression in skin (RPKM 27.0), ovary (RPKM 14.2) and 18 other tissues See more
    Orthologs
    mouse all
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    Genomic context

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    See PTPN13 in Genome Data Viewer
    Location:
    4q21.3
    Exon count:
    49
    Annotation release Status Assembly Chr Location
    RS_2024_08 current GRCh38.p14 (GCF_000001405.40) 4 NC_000004.12 (86594315..86815161)
    RS_2024_08 current T2T-CHM13v2.0 (GCF_009914755.1) 4 NC_060928.1 (89923800..90144654)
    RS_2024_09 previous assembly GRCh37.p13 (GCF_000001405.25) 4 NC_000004.11 (87515468..87736314)

    Chromosome 4 - NC_000004.12Genomic Context describing neighboring genes Neighboring gene mitogen-activated protein kinase 10 Neighboring gene RN7SK pseudogene 96 Neighboring gene NANOG hESC enhancer GRCh37_chr4:87353806-87354348 Neighboring gene H3K27ac-H3K4me1 hESC enhancer GRCh37_chr4:87374354-87374902 Neighboring gene OCT4-NANOG hESC enhancer GRCh37_chr4:87393729-87394298 Neighboring gene H3K27ac hESC enhancer GRCh37_chr4:87398123-87398623 Neighboring gene OCT4-NANOG-H3K27ac-H3K4me1 hESC enhancer GRCh37_chr4:87403957-87404713 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 21695 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr4:87468519-87469019 Neighboring gene H3K27ac hESC enhancer GRCh37_chr4:87515119-87515705 Neighboring gene microRNA 4452 Neighboring gene ATAC-STARR-seq lymphoblastoid silent region 15548 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr4:87651683-87652182 Neighboring gene OCT4-NANOG-H3K4me1 hESC enhancer GRCh37_chr4:87778666-87779166 Neighboring gene solute carrier family 10 member 6 Neighboring gene ribosomal protein L6 pseudogene 13

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Crystallographic and nuclear magnetic resonance evaluation of the impact of peptide binding to the second PDZ domain of protein tyrosine phosphatase 1E. Zhang J, et al. Biochemistry, 2010 Nov 2. PMID 20839809, Free PMC Article
    2. ESI-MS and FTIR studies of the interaction between the second PDZ domain of hPTP1E and target peptides. Papp R, et al. Biochem Cell Biol, 2003 Apr. PMID 12870871
    3. Structure determination and ligand interactions of the PDZ2b domain of PTP-Bas (hPTP1E): splicing-induced modulation of ligand specificity. Kachel N, et al. J Mol Biol, 2003 Nov 14. PMID 14596806
    4. PTPL1 is a direct transcriptional target of EWS-FLI1 and modulates Ewing's Sarcoma tumorigenesis. Abaan OD, et al. Oncogene, 2005 Apr 14. PMID 15782144
    5. Immunohistochemical Localization of Fas-associated phosphatase-1 (FAP-1) in Alzheimer disease hippocampus. Savaskan E, et al. Appl Immunohistochem Mol Morphol, 2005 Jun. PMID 15894934

    See all (180) citations in PubMed

    GeneRIFs: Gene References Into Functions

    What's a GeneRIF?
    1. METTL1/FOXM1 promotes lung adenocarcinoma progression and gefitinib resistance by inhibiting PTPN13 expression.
      Title: METTL1/FOXM1 promotes lung adenocarcinoma progression and gefitinib resistance by inhibiting PTPN13 expression.
    2. PTPN13 rs989902 and CHEK2 rs738722 are associated with esophageal cancer.
      Title: PTPN13 rs989902 and CHEK2 rs738722 are associated with esophageal cancer.
    3. Protein tyrosine phosphatase PTPL1 suppresses lung cancer through Src/ERK/YAP1 signaling.
      Title: Protein tyrosine phosphatase PTPL1 suppresses lung cancer through Src/ERK/YAP1 signaling.
    4. Germline PTPN13 mutations in patients with bone marrow failure and acute lymphoblastic leukemia.
      Title: Germline PTPN13 mutations in patients with bone marrow failure and acute lymphoblastic leukemia.
    5. PTPL1 suppresses lung cancer cell migration via inhibiting TGF-beta1-induced activation of p38 MAPK and Smad 2/3 pathways and EMT.
      Title: PTPL1 suppresses lung cancer cell migration via inhibiting TGF-β1-induced activation of p38 MAPK and Smad 2/3 pathways and EMT.
    6. Anti-oncogene PTPN13 inactivation by hepatitis B virus X protein counteracts IGF2BP1 to promote hepatocellular carcinoma progression.
      Title: Anti-oncogene PTPN13 inactivation by hepatitis B virus X protein counteracts IGF2BP1 to promote hepatocellular carcinoma progression.
    7. PTPN13 induces cell junction stabilization and inhibits mammary tumor invasiveness.
      Title: PTPN13 induces cell junction stabilization and inhibits mammary tumor invasiveness.
    8. PTPN13 acts as a tumor suppressor in clear cell renal cell carcinoma by inactivating Akt signaling.
      Title: PTPN13 acts as a tumor suppressor in clear cell renal cell carcinoma by inactivating Akt signaling.
    9. This work demonstrates a novel function for PTEN during cell polarization in controlling apical membrane size and identifies PTPL1 as a critical apical membrane anchor for PTEN in this process.
      Title: The Phosphatase PTPL1 Is Required for PTEN-Mediated Regulation of Apical Membrane Size.
    10. MicroRNA-30e-5p promotes cell growth by targeting PTPN13 and indicates poor survival and recurrence in lung adenocarcinoma.
      Title: MicroRNA-30e-5p promotes cell growth by targeting PTPN13 and indicates poor survival and recurrence in lung adenocarcinoma.
    Submit: New GeneRIF Correction See all GeneRIFs (70)

    Phenotypes

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    Find tests for this gene in the NIH Genetic Testing Registry (GTR)

    Review eQTL and phenotype association data in this region using PheGenI

    EBI GWAS Catalog

    Description
    Genome-wide association study on dimethylarginines reveals novel AGXT2 variants associated with heart rate variability but not with overall mortality.
    EBI GWAS Catalog

    Variation

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    See variants in ClinVar

    See studies and variants in dbVar

    See Variation Viewer (GRCh37.p13)

    See Variation Viewer (GRCh38)

    Pathways from PubChem

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    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Markers

    Homology

    Clone Names

    • DKFZp686J1497

    Gene Ontology Provided by GOA

    Function Evidence Code Pubs
    enables histone H2AXY142 phosphatase activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables non-membrane spanning protein tyrosine phosphatase activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables phosphatidylinositol 3-kinase regulatory subunit binding IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    enables phosphatidylinositol 3-kinase regulatory subunit binding IPI
    Inferred from Physical Interaction
    more info
    		 PubMed 
    enables protein binding IPI
    Inferred from Physical Interaction
    more info
    		 PubMed 
    enables protein tyrosine phosphatase activity IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    enables protein tyrosine phosphatase activity IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    enables protein tyrosine phosphatase activity IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    enables protein tyrosine phosphatase activity, metal-dependent IEA
    Inferred from Electronic Annotation
    more info
    		  
    Process Evidence Code Pubs
    involved_in cellular response to toxic substance IEA
    Inferred from Electronic Annotation
    more info
    		  
    involved_in chromatin remodeling IEA
    Inferred from Electronic Annotation
    more info
    		  
    involved_in negative regulation of excitatory synapse assembly IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    involved_in negative regulation of protein phosphorylation IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    involved_in peptidyl-tyrosine dephosphorylation IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    involved_in protein dephosphorylation IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    involved_in regulation of phosphatidylinositol 3-kinase/protein kinase B signal transduction IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    involved_in regulation of phosphatidylinositol 3-kinase/protein kinase B signal transduction IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in cell body IEA
    Inferred from Electronic Annotation
    more info
    		  
    is_active_in cytoplasm IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    located_in cytoplasm IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    located_in cytoskeleton IEA
    Inferred from Electronic Annotation
    more info
    		  
    located_in cytosol IDA
    Inferred from Direct Assay
    more info
    		  
    located_in extracellular exosome HDA PubMed 
    located_in fibrillar center IDA
    Inferred from Direct Assay
    more info
    		  
    located_in lamellipodium IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    located_in nucleoplasm IDA
    Inferred from Direct Assay
    more info
    		  
    located_in nucleoplasm TAS
    Traceable Author Statement
    more info
    		  
    is_active_in nucleus IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    located_in nucleus IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    located_in plasma membrane IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    located_in plasma membrane TAS
    Traceable Author Statement
    more info
    		  

    General protein information

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    Preferred Names
    tyrosine-protein phosphatase non-receptor type 13
    Names
    fas-associated protein-tyrosine phosphatase 1
    hPTPE1
    protein tyrosine phosphatase, non-receptor type 13 (APO-1/CD95 (Fas)-associated phosphatase)
    protein-tyrosine phosphatase 1E
    protein-tyrosine phosphatase PTPL1
    NP_006255.1
    NP_542414.1
    NP_542415.1
    NP_542416.1
    XP_011530467.1
    XP_016864000.1
    XP_016864001.1
    XP_016864002.1
    XP_016864003.1
    XP_016864004.1
    XP_016864005.1
    XP_047271992.1
    XP_047271993.1
    XP_047271994.1
    XP_047271995.1
    XP_047271996.1
    XP_047271997.1
    XP_047271998.1
    XP_047271999.1
    XP_047272000.1
    XP_047272001.1
    XP_047272002.1
    XP_047272003.1
    XP_047272004.1
    XP_054206615.1
    XP_054206616.1
    XP_054206617.1
    XP_054206618.1
    XP_054206619.1
    XP_054206620.1
    XP_054206621.1
    XP_054206622.1
    XP_054206623.1
    XP_054206624.1
    XP_054206625.1
    XP_054206626.1
    XP_054206627.1
    XP_054206628.1
    XP_054206629.1
    XP_054206630.1
    XP_054206631.1
    XP_054206632.1
    XP_054206633.1

    NCBI Reference Sequences (RefSeq)

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    NEW Try the new Transcript table

    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    Genomic

    1. NG_029704.1 RefSeqGene

      Range
      5001..225847
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_006264.3 → NP_006255.1  tyrosine-protein phosphatase non-receptor type 13 isoform 2

      See identical proteins and their annotated locations for NP_006255.1

      Status: REVIEWED

      Description
      Transcript Variant: This variant (2) lacks multiple in-frame segments of the coding region, compared to variant 4. The encoded protein (isoform 2) lacks 19 internal amino acids, compared to isoform 4.
      Source sequence(s)
      BG202767, D21210, DA625835
      Consensus CDS
      CCDS47095.1
      UniProtKB/TrEMBL
      Q59H55
      Related
      ENSP00000408368.2, ENST00000427191.6
      Conserved Domains (10) summary
      smart00194
      Location:2195 → 2447
      PTPc; Protein tyrosine phosphatase, catalytic domain
      smart00228
      Location:1479 → 1570
      PDZ; Domain present in PSD-95, Dlg, and ZO-1/2
      smart00295
      Location:573 → 781
      B41; Band 4.1 homologues
      smart00750
      Location:3 → 190
      KIND; kinase non-catalytic C-lobe domain
      cd00047
      Location:2221 → 2447
      PTPc; Protein tyrosine phosphatases (PTP) catalyze the dephosphorylation of phosphotyrosine peptides; they regulate phosphotyrosine levels in signal transduction pathways. The depth of the active site cleft renders the enzyme specific for phosphorylated Tyr ...
      cd00992
      Location:1072 → 1156
      PDZ_signaling; PDZ domain found in a variety of Eumetazoan signaling molecules, often in tandem arrangements. May be responsible for specific protein-protein interactions, as most PDZ domains bind C-terminal polypeptides, and binding to internal (non-C-terminal) ...
      pfam00373
      Location:668 → 781
      FERM_M; FERM central domain
      pfam09379
      Location:576 → 638
      FERM_N; FERM N-terminal domain
      pfam16599
      Location:1158 → 1348
      PTN13_u3; Unstructured linker region on PTN13 protein between PDZ
      cl17171
      Location:777 → 877
      PH-like; Pleckstrin homology-like domain

    2. NM_080683.3 → NP_542414.1  tyrosine-protein phosphatase non-receptor type 13 isoform 1

      See identical proteins and their annotated locations for NP_542414.1

      Status: REVIEWED

      Description
      Transcript Variant: This variant (1) lacks an in-frame segment of a coding exon, compared to variant 4. The encoded protein (isoform 1) lacks 5 internal amino acids, compared to isoform 4.
      Source sequence(s)
      BG202767, D21209, DA625835
      Consensus CDS
      CCDS47094.1
      UniProtKB/Swiss-Prot
      B2RTR0, Q12923, Q15159, Q15263, Q15264, Q15265, Q15674, Q16826, Q8IWH7, Q9NYN9, Q9UDA8
      UniProtKB/TrEMBL
      Q59H55
      Related
      ENSP00000407249.2, ENST00000411767.7
      Conserved Domains (10) summary
      smart00194
      Location:2214 → 2466
      PTPc; Protein tyrosine phosphatase, catalytic domain
      smart00228
      Location:1498 → 1589
      PDZ; Domain present in PSD-95, Dlg, and ZO-1/2
      smart00295
      Location:573 → 781
      B41; Band 4.1 homologues
      smart00750
      Location:3 → 190
      KIND; kinase non-catalytic C-lobe domain
      cd00047
      Location:2240 → 2466
      PTPc; Protein tyrosine phosphatases (PTP) catalyze the dephosphorylation of phosphotyrosine peptides; they regulate phosphotyrosine levels in signal transduction pathways. The depth of the active site cleft renders the enzyme specific for phosphorylated Tyr ...
      cd00992
      Location:1091 → 1175
      PDZ_signaling; PDZ domain found in a variety of Eumetazoan signaling molecules, often in tandem arrangements. May be responsible for specific protein-protein interactions, as most PDZ domains bind C-terminal polypeptides, and binding to internal (non-C-terminal) ...
      pfam00373
      Location:668 → 781
      FERM_M; FERM central domain
      pfam09379
      Location:576 → 638
      FERM_N; FERM N-terminal domain
      pfam16599
      Location:1177 → 1367
      PTN13_u3; Unstructured linker region on PTN13 protein between PDZ
      cl17171
      Location:777 → 877
      PH-like; Pleckstrin homology-like domain

    3. NM_080684.3 → NP_542415.1  tyrosine-protein phosphatase non-receptor type 13 isoform 3

      See identical proteins and their annotated locations for NP_542415.1

      Status: REVIEWED

      Description
      Transcript Variant: This variant (3) lacks multiple in-frame segments of the coding region, compared to variant 4. The encoded protein (isoform 3) lacks 191 internal amino acids, compared to isoform 4.
      Source sequence(s)
      BG202767, D21211, DA625835
      Consensus CDS
      CCDS47096.1
      UniProtKB/TrEMBL
      Q59H55
      Related
      ENSP00000322675.6, ENST00000316707.10
      Conserved Domains (10) summary
      smart00194
      Location:2023 → 2275
      PTPc; Protein tyrosine phosphatase, catalytic domain
      smart00228
      Location:1307 → 1398
      PDZ; Domain present in PSD-95, Dlg, and ZO-1/2
      smart00295
      Location:573 → 781
      B41; Band 4.1 homologues
      smart00750
      Location:3 → 190
      KIND; kinase non-catalytic C-lobe domain
      cd00047
      Location:2049 → 2275
      PTPc; Protein tyrosine phosphatases (PTP) catalyze the dephosphorylation of phosphotyrosine peptides; they regulate phosphotyrosine levels in signal transduction pathways. The depth of the active site cleft renders the enzyme specific for phosphorylated Tyr ...
      cd00992
      Location:900 → 984
      PDZ_signaling; PDZ domain found in a variety of Eumetazoan signaling molecules, often in tandem arrangements. May be responsible for specific protein-protein interactions, as most PDZ domains bind C-terminal polypeptides, and binding to internal (non-C-terminal) ...
      pfam00373
      Location:668 → 781
      FERM_M; FERM central domain
      pfam09379
      Location:576 → 638
      FERM_N; FERM N-terminal domain
      pfam16599
      Location:986 → 1176
      PTN13_u3; Unstructured linker region on PTN13 protein between PDZ
      cl17171
      Location:777 → 877
      PH-like; Pleckstrin homology-like domain

    4. NM_080685.3 → NP_542416.1  tyrosine-protein phosphatase non-receptor type 13 isoform 4

      See identical proteins and their annotated locations for NP_542416.1

      Status: REVIEWED

      Description
      Transcript Variant: This variant (4) encodes the longest isoform (4).
      Source sequence(s)
      BG202767, D21209, DA625835, L34583
      Consensus CDS
      CCDS47093.1
      UniProtKB/TrEMBL
      Q59H55
      Related
      ENSP00000394794.1, ENST00000436978.5
      Conserved Domains (10) summary
      smart00194
      Location:2219 → 2471
      PTPc; Protein tyrosine phosphatase, catalytic domain
      smart00228
      Location:1503 → 1594
      PDZ; Domain present in PSD-95, Dlg, and ZO-1/2
      smart00295
      Location:573 → 781
      B41; Band 4.1 homologues
      smart00750
      Location:3 → 190
      KIND; kinase non-catalytic C-lobe domain
      cd00047
      Location:2245 → 2471
      PTPc; Protein tyrosine phosphatases (PTP) catalyze the dephosphorylation of phosphotyrosine peptides; they regulate phosphotyrosine levels in signal transduction pathways. The depth of the active site cleft renders the enzyme specific for phosphorylated Tyr ...
      cd00992
      Location:1091 → 1175
      PDZ_signaling; PDZ domain found in a variety of Eumetazoan signaling molecules, often in tandem arrangements. May be responsible for specific protein-protein interactions, as most PDZ domains bind C-terminal polypeptides, and binding to internal (non-C-terminal) ...
      pfam00373
      Location:668 → 781
      FERM_M; FERM central domain
      pfam09379
      Location:576 → 638
      FERM_N; FERM N-terminal domain
      pfam16599
      Location:1177 → 1367
      PTN13_u3; Unstructured linker region on PTN13 protein between PDZ
      cl17171
      Location:777 → 877
      PH-like; Pleckstrin homology-like domain

    RefSeqs of Annotated Genomes: GCF_000001405.40-RS_2024_08

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCh38.p14 Primary Assembly

    Genomic

    1. NC_000004.12 Reference GRCh38.p14 Primary Assembly

      Range
      86594315..86815161
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_011532165.3 → XP_011530467.1  tyrosine-protein phosphatase non-receptor type 13 isoform X1

      UniProtKB/TrEMBL
      Q59H55
      Conserved Domains (10) summary
      smart00194
      Location:2236 → 2488
      PTPc; Protein tyrosine phosphatase, catalytic domain
      smart00228
      Location:1503 → 1594
      PDZ; Domain present in PSD-95, Dlg, and ZO-1/2
      smart00295
      Location:573 → 781
      B41; Band 4.1 homologues
      smart00750
      Location:3 → 190
      KIND; kinase non-catalytic C-lobe domain
      cd00047
      Location:2262 → 2488
      PTPc; Protein tyrosine phosphatases (PTP) catalyze the dephosphorylation of phosphotyrosine peptides; they regulate phosphotyrosine levels in signal transduction pathways. The depth of the active site cleft renders the enzyme specific for phosphorylated Tyr ...
      cd00992
      Location:1091 → 1175
      PDZ_signaling; PDZ domain found in a variety of Eumetazoan signaling molecules, often in tandem arrangements. May be responsible for specific protein-protein interactions, as most PDZ domains bind C-terminal polypeptides, and binding to internal (non-C-terminal) ...
      pfam00373
      Location:668 → 781
      FERM_M; FERM central domain
      pfam09379
      Location:576 → 638
      FERM_N; FERM N-terminal domain
      pfam16599
      Location:1177 → 1367
      PTN13_u3; Unstructured linker region on PTN13 protein between PDZ
      cl17171
      Location:777 → 877
      PH-like; Pleckstrin homology-like domain

    2. XM_017008511.3 → XP_016864000.1  tyrosine-protein phosphatase non-receptor type 13 isoform X2

      UniProtKB/TrEMBL
      Q59H55

    3. XM_017008512.3 → XP_016864001.1  tyrosine-protein phosphatase non-receptor type 13 isoform X3

      UniProtKB/TrEMBL
      Q59H55

    4. XM_017008514.3 → XP_016864003.1  tyrosine-protein phosphatase non-receptor type 13 isoform X5

      UniProtKB/TrEMBL
      Q59H55

    5. XM_017008513.3 → XP_016864002.1  tyrosine-protein phosphatase non-receptor type 13 isoform X4

      UniProtKB/TrEMBL
      Q59H55

    6. XM_017008516.3 → XP_016864005.1  tyrosine-protein phosphatase non-receptor type 13 isoform X8

      UniProtKB/TrEMBL
      Q59H55

    7. XM_047416041.1 → XP_047271997.1  tyrosine-protein phosphatase non-receptor type 13 isoform X13

      UniProtKB/TrEMBL
      Q59H55

    8. XM_047416038.1 → XP_047271994.1  tyrosine-protein phosphatase non-receptor type 13 isoform X10

      UniProtKB/TrEMBL
      Q59H55

    9. XM_017008515.3 → XP_016864004.1  tyrosine-protein phosphatase non-receptor type 13 isoform X7

      UniProtKB/TrEMBL
      Q59H55

    10. XM_047416039.1 → XP_047271995.1  tyrosine-protein phosphatase non-receptor type 13 isoform X11

      UniProtKB/TrEMBL
      Q59H55

    11. XM_047416037.1 → XP_047271993.1  tyrosine-protein phosphatase non-receptor type 13 isoform X9

      UniProtKB/TrEMBL
      Q59H55

    12. XM_047416042.1 → XP_047271998.1  tyrosine-protein phosphatase non-receptor type 13 isoform X14

      UniProtKB/TrEMBL
      Q59H55

    13. XM_047416040.1 → XP_047271996.1  tyrosine-protein phosphatase non-receptor type 13 isoform X12

      UniProtKB/TrEMBL
      Q59H55

    14. XM_047416044.1 → XP_047272000.1  tyrosine-protein phosphatase non-receptor type 13 isoform X16

      UniProtKB/TrEMBL
      Q59H55

    15. XM_047416043.1 → XP_047271999.1  tyrosine-protein phosphatase non-receptor type 13 isoform X15

      UniProtKB/TrEMBL
      Q59H55

    16. XM_047416045.1 → XP_047272001.1  tyrosine-protein phosphatase non-receptor type 13 isoform X17

      UniProtKB/TrEMBL
      Q59H55

    17. XM_047416047.1 → XP_047272003.1  tyrosine-protein phosphatase non-receptor type 13 isoform X19

      UniProtKB/TrEMBL
      Q59H55

    18. XM_047416046.1 → XP_047272002.1  tyrosine-protein phosphatase non-receptor type 13 isoform X18

      UniProtKB/TrEMBL
      Q59H55

    19. XM_047416048.1 → XP_047272004.1  tyrosine-protein phosphatase non-receptor type 13 isoform X20

      UniProtKB/TrEMBL
      Q59H55

    20. XM_047416036.1 → XP_047271992.1  tyrosine-protein phosphatase non-receptor type 13 isoform X6

      UniProtKB/TrEMBL
      Q59H55

    Alternate T2T-CHM13v2.0

    Genomic

    1. NC_060928.1 Alternate T2T-CHM13v2.0

      Range
      89923800..90144654
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_054350640.1 → XP_054206615.1  tyrosine-protein phosphatase non-receptor type 13 isoform X1

      UniProtKB/TrEMBL
      Q59H55

    2. XM_054350641.1 → XP_054206616.1  tyrosine-protein phosphatase non-receptor type 13 isoform X2

      UniProtKB/TrEMBL
      Q59H55

    3. XM_054350642.1 → XP_054206617.1  tyrosine-protein phosphatase non-receptor type 13 isoform X3

      UniProtKB/TrEMBL
      Q59H55

    4. XM_054350644.1 → XP_054206619.1  tyrosine-protein phosphatase non-receptor type 13 isoform X5

      UniProtKB/TrEMBL
      Q59H55

    5. XM_054350643.1 → XP_054206618.1  tyrosine-protein phosphatase non-receptor type 13 isoform X4

      UniProtKB/TrEMBL
      Q59H55

    6. XM_054350646.1 → XP_054206621.1  tyrosine-protein phosphatase non-receptor type 13 isoform X8

      UniProtKB/TrEMBL
      Q59H55

    7. XM_054350651.1 → XP_054206626.1  tyrosine-protein phosphatase non-receptor type 13 isoform X13

      UniProtKB/TrEMBL
      Q59H55

    8. XM_054350648.1 → XP_054206623.1  tyrosine-protein phosphatase non-receptor type 13 isoform X10

      UniProtKB/TrEMBL
      Q59H55

    9. XM_054350645.1 → XP_054206620.1  tyrosine-protein phosphatase non-receptor type 13 isoform X7

      UniProtKB/TrEMBL
      Q59H55

    10. XM_054350649.1 → XP_054206624.1  tyrosine-protein phosphatase non-receptor type 13 isoform X11

      UniProtKB/TrEMBL
      Q59H55

    11. XM_054350647.1 → XP_054206622.1  tyrosine-protein phosphatase non-receptor type 13 isoform X9

      UniProtKB/TrEMBL
      Q59H55

    12. XM_054350652.1 → XP_054206627.1  tyrosine-protein phosphatase non-receptor type 13 isoform X14

      UniProtKB/TrEMBL
      Q59H55

    13. XM_054350650.1 → XP_054206625.1  tyrosine-protein phosphatase non-receptor type 13 isoform X12

      UniProtKB/TrEMBL
      Q59H55

    14. XM_054350654.1 → XP_054206629.1  tyrosine-protein phosphatase non-receptor type 13 isoform X16

      UniProtKB/TrEMBL
      Q59H55

    15. XM_054350653.1 → XP_054206628.1  tyrosine-protein phosphatase non-receptor type 13 isoform X15

      UniProtKB/TrEMBL
      Q59H55

    16. XM_054350655.1 → XP_054206630.1  tyrosine-protein phosphatase non-receptor type 13 isoform X17

      UniProtKB/TrEMBL
      Q59H55

    17. XM_054350657.1 → XP_054206632.1  tyrosine-protein phosphatase non-receptor type 13 isoform X19

      UniProtKB/TrEMBL
      Q59H55

    18. XM_054350656.1 → XP_054206631.1  tyrosine-protein phosphatase non-receptor type 13 isoform X18

      UniProtKB/TrEMBL
      Q59H55

    19. XM_054350658.1 → XP_054206633.1  tyrosine-protein phosphatase non-receptor type 13 isoform X20

      UniProtKB/TrEMBL
      Q59H55
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q12923.2 GenPept UniProtKB/Swiss-Prot:Q12923

    Gene LinkOut

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