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These reference sequences exist independently of genome builds. Explain
These reference sequences are curated independently of the genome
annotation cycle, so their versions may not match the RefSeq versions in the current
genome build. Identify version mismatches by comparing the version of the RefSeq in
this section to the one reported in Genomic regions,
transcripts, and products above.
Genomic
-
NG_011487.2 RefSeqGene
- Range
-
4908..1441520
- Download
- GenBank, FASTA, Sequence Viewer (Graphics)
mRNA and Protein(s)
-
NM_001301128.2 → NP_001288057.1 membrane-associated guanylate kinase, WW and PDZ domain-containing protein 2 isoform 2
See identical proteins and their annotated locations for NP_001288057.1
Status: REVIEWED
- Description
- Transcript Variant: This variant (2) lacks an in-frame exon in the central coding region, compared to variant 1. The encoded isoform (2) is shorter, compared to isoform 1.
- Source sequence(s)
-
AA448362, AA890379, AB014605, AC004808, AC004945, AC004990, AF038563, AK297353, Z19922
- Consensus CDS
-
CCDS75623.1
- UniProtKB/TrEMBL
-
B7Z4H4
- Related
- ENSP00000405766.1, ENST00000419488.5
- Conserved Domains (6) summary
-
- smart00072
Location:118 → 291
- GuKc; Guanylate kinase homologues
- smart00228
Location:761 → 847
- PDZ; Domain present in PSD-95, Dlg, and ZO-1/2
- cd00201
Location:305 → 335
- WW; Two conserved tryptophans domain; also known as the WWP or rsp5 domain; around 40 amino acids; functions as an interaction module in a diverse set of signalling proteins; binds specific proline-rich sequences but at low affinities compared to other ...
- cd00992
Location:1132 → 1212
- PDZ_signaling; PDZ domain found in a variety of Eumetazoan signaling molecules, often in tandem arrangements. May be responsible for specific protein-protein interactions, as most PDZ domains bind C-terminal polypeptides, and binding to internal (non-C-terminal) ...
- pfam00397
Location:350 → 379
- WW; WW domain
- pfam16666
Location:682 → 756
- MAGI_u5; Unstructured region on MAGI
-
NM_012301.4 → NP_036433.2 membrane-associated guanylate kinase, WW and PDZ domain-containing protein 2 isoform 1
See identical proteins and their annotated locations for NP_036433.2
Status: REVIEWED
- Description
- Transcript Variant: This variant (1) represents the longer transcript and encodes the longer isoform (1).
- Source sequence(s)
-
AA448362, AB014605, AC004808, AC004945, AC004990, AC007237, AF038563
- Consensus CDS
-
CCDS5594.1
- UniProtKB/Swiss-Prot
- A4D1C1, A7E2C3, O60434, O60510, Q86UI7, Q86UL8, Q9NP44, Q9UDQ5, Q9UDU1
- UniProtKB/TrEMBL
-
B7Z4H4
- Related
- ENSP00000346151.4, ENST00000354212.9
- Conserved Domains (6) summary
-
- smart00072
Location:118 → 291
- GuKc; Guanylate kinase homologues
- smart00228
Location:775 → 861
- PDZ; Domain present in PSD-95, Dlg, and ZO-1/2
- cd00201
Location:305 → 335
- WW; Two conserved tryptophans domain; also known as the WWP or rsp5 domain; around 40 amino acids; functions as an interaction module in a diverse set of signalling proteins; binds specific proline-rich sequences but at low affinities compared to other ...
- cd00992
Location:1146 → 1226
- PDZ_signaling; PDZ domain found in a variety of Eumetazoan signaling molecules, often in tandem arrangements. May be responsible for specific protein-protein interactions, as most PDZ domains bind C-terminal polypeptides, and binding to internal (non-C-terminal) ...
- pfam00397
Location:350 → 379
- WW; WW domain
- pfam16666
Location:682 → 756
- MAGI_u5; Unstructured region on MAGI
The following sections contain reference sequences that belong to a
specific genome build. Explain
This section includes genomic Reference
Sequences (RefSeqs) from all assemblies on which this gene is annotated, such as
RefSeqs for chromosomes and scaffolds (contigs) from both reference and alternate
assemblies. Model RNAs and proteins are also reported here.
Reference GRCh38.p14 Primary Assembly
Genomic
-
NC_000007.14 Reference GRCh38.p14 Primary Assembly
- Range
-
78017055..79453667 complement
- Download
- GenBank, FASTA, Sequence Viewer (Graphics)
mRNA and Protein(s)
-
XM_047421093.1 → XP_047277049.1 membrane-associated guanylate kinase, WW and PDZ domain-containing protein 2 isoform X10
- UniProtKB/TrEMBL
-
B7Z4H4
-
XM_017012845.3 → XP_016868334.1 membrane-associated guanylate kinase, WW and PDZ domain-containing protein 2 isoform X7
- UniProtKB/TrEMBL
-
B7Z4H4
-
XM_017012846.3 → XP_016868335.1 membrane-associated guanylate kinase, WW and PDZ domain-containing protein 2 isoform X9
- UniProtKB/TrEMBL
-
B7Z4H4
-
XM_011516718.3 → XP_011515020.1 membrane-associated guanylate kinase, WW and PDZ domain-containing protein 2 isoform X6
- UniProtKB/TrEMBL
-
B7Z4H4
- Related
- ENSP00000428389.1, ENST00000522391.3
- Conserved Domains (6) summary
-
- smart00072
Location:118 → 291
- GuKc; Guanylate kinase homologues
- smart00228
Location:775 → 861
- PDZ; Domain present in PSD-95, Dlg, and ZO-1/2
- cd00201
Location:305 → 335
- WW; Two conserved tryptophans domain; also known as the WWP or rsp5 domain; around 40 amino acids; functions as an interaction module in a diverse set of signalling proteins; binds specific proline-rich sequences but at low affinities compared to other ...
- cd00992
Location:1146 → 1226
- PDZ_signaling; PDZ domain found in a variety of Eumetazoan signaling molecules, often in tandem arrangements. May be responsible for specific protein-protein interactions, as most PDZ domains bind C-terminal polypeptides, and binding to internal (non-C-terminal) ...
- pfam00397
Location:350 → 379
- WW; WW domain
- pfam16666
Location:682 → 756
- MAGI_u5; Unstructured region on MAGI
-
XM_017012841.3 → XP_016868330.1 membrane-associated guanylate kinase, WW and PDZ domain-containing protein 2 isoform X2
- UniProtKB/TrEMBL
-
B7Z4H4
-
XM_017012842.3 → XP_016868331.1 membrane-associated guanylate kinase, WW and PDZ domain-containing protein 2 isoform X3
- UniProtKB/TrEMBL
-
B7Z4H4
-
XM_047421092.1 → XP_047277048.1 membrane-associated guanylate kinase, WW and PDZ domain-containing protein 2 isoform X8
- UniProtKB/TrEMBL
-
B7Z4H4
-
XM_017012843.3 → XP_016868332.1 membrane-associated guanylate kinase, WW and PDZ domain-containing protein 2 isoform X4
- UniProtKB/TrEMBL
-
B7Z4H4
-
XM_017012844.3 → XP_016868333.1 membrane-associated guanylate kinase, WW and PDZ domain-containing protein 2 isoform X5
- UniProtKB/TrEMBL
-
B7Z4H4
-
XM_017012840.3 → XP_016868329.1 membrane-associated guanylate kinase, WW and PDZ domain-containing protein 2 isoform X1
- UniProtKB/TrEMBL
-
B7Z4H4
-
XM_017012847.3 → XP_016868336.1 membrane-associated guanylate kinase, WW and PDZ domain-containing protein 2 isoform X11
- UniProtKB/TrEMBL
-
A0A0D9SEY4
- Conserved Domains (7) summary
-
- smart00228
Location:655 → 741
- PDZ; Domain present in PSD-95, Dlg, and ZO-1/2
- cd00201
Location:142 → 172
- WW; Two conserved tryptophans domain; also known as the WWP or rsp5 domain; around 40 amino acids; functions as an interaction module in a diverse set of signalling proteins; binds specific proline-rich sequences but at low affinities compared to other ...
- cd00992
Location:1026 → 1106
- PDZ_signaling; PDZ domain found in a variety of Eumetazoan signaling molecules, often in tandem arrangements. May be responsible for specific protein-protein interactions, as most PDZ domains bind C-terminal polypeptides, and binding to internal (non-C-terminal) ...
- pfam00397
Location:187 → 216
- WW; WW domain
- pfam16663
Location:35 → 96
- MAGI_u1; Unstructured region on MAGI
- pfam16666
Location:562 → 636
- MAGI_u5; Unstructured region on MAGI
- cl17190
Location:1 → 128
- NK; Nucleoside/nucleotide kinase (NK) is a protein superfamily consisting of multiple families of enzymes that share structural similarity and are functionally related to the catalysis of the reversible phosphate group transfer from nucleoside triphosphates ...
-
XM_011516720.4 → XP_011515022.1 membrane-associated guanylate kinase, WW and PDZ domain-containing protein 2 isoform X11
See identical proteins and their annotated locations for XP_011515022.1
- UniProtKB/TrEMBL
-
A0A0D9SEY4
- Related
- ENSP00000486131.1, ENST00000626691.2
- Conserved Domains (7) summary
-
- smart00228
Location:655 → 741
- PDZ; Domain present in PSD-95, Dlg, and ZO-1/2
- cd00201
Location:142 → 172
- WW; Two conserved tryptophans domain; also known as the WWP or rsp5 domain; around 40 amino acids; functions as an interaction module in a diverse set of signalling proteins; binds specific proline-rich sequences but at low affinities compared to other ...
- cd00992
Location:1026 → 1106
- PDZ_signaling; PDZ domain found in a variety of Eumetazoan signaling molecules, often in tandem arrangements. May be responsible for specific protein-protein interactions, as most PDZ domains bind C-terminal polypeptides, and binding to internal (non-C-terminal) ...
- pfam00397
Location:187 → 216
- WW; WW domain
- pfam16663
Location:35 → 96
- MAGI_u1; Unstructured region on MAGI
- pfam16666
Location:562 → 636
- MAGI_u5; Unstructured region on MAGI
- cl17190
Location:1 → 128
- NK; Nucleoside/nucleotide kinase (NK) is a protein superfamily consisting of multiple families of enzymes that share structural similarity and are functionally related to the catalysis of the reversible phosphate group transfer from nucleoside triphosphates ...
-
XM_011516728.2 → XP_011515030.1 membrane-associated guanylate kinase, WW and PDZ domain-containing protein 2 isoform X12
- Conserved Domains (3) summary
-
- smart00228
Location:384 → 470
- PDZ; Domain present in PSD-95, Dlg, and ZO-1/2
- cd00992
Location:755 → 835
- PDZ_signaling; PDZ domain found in a variety of Eumetazoan signaling molecules, often in tandem arrangements. May be responsible for specific protein-protein interactions, as most PDZ domains bind C-terminal polypeptides, and binding to internal (non-C-terminal) ...
- pfam16666
Location:291 → 365
- MAGI_u5; Unstructured region on MAGI
Alternate T2T-CHM13v2.0
Genomic
-
NC_060931.1 Alternate T2T-CHM13v2.0
- Range
-
79268893..80705470 complement
- Download
- GenBank, FASTA, Sequence Viewer (Graphics)
mRNA and Protein(s)
-
XM_054359444.1 → XP_054215419.1 membrane-associated guanylate kinase, WW and PDZ domain-containing protein 2 isoform X10
- UniProtKB/TrEMBL
-
B7Z4H4
-
XM_054359441.1 → XP_054215416.1 membrane-associated guanylate kinase, WW and PDZ domain-containing protein 2 isoform X7
- UniProtKB/TrEMBL
-
B7Z4H4
-
XM_054359443.1 → XP_054215418.1 membrane-associated guanylate kinase, WW and PDZ domain-containing protein 2 isoform X9
- UniProtKB/TrEMBL
-
B7Z4H4
-
XM_054359440.1 → XP_054215415.1 membrane-associated guanylate kinase, WW and PDZ domain-containing protein 2 isoform X6
- UniProtKB/TrEMBL
-
B7Z4H4
-
XM_054359436.1 → XP_054215411.1 membrane-associated guanylate kinase, WW and PDZ domain-containing protein 2 isoform X2
- UniProtKB/TrEMBL
-
B7Z4H4
-
XM_054359437.1 → XP_054215412.1 membrane-associated guanylate kinase, WW and PDZ domain-containing protein 2 isoform X3
- UniProtKB/TrEMBL
-
B7Z4H4
-
XM_054359442.1 → XP_054215417.1 membrane-associated guanylate kinase, WW and PDZ domain-containing protein 2 isoform X8
- UniProtKB/TrEMBL
-
B7Z4H4
-
XM_054359438.1 → XP_054215413.1 membrane-associated guanylate kinase, WW and PDZ domain-containing protein 2 isoform X4
- UniProtKB/TrEMBL
-
B7Z4H4
-
XM_054359439.1 → XP_054215414.1 membrane-associated guanylate kinase, WW and PDZ domain-containing protein 2 isoform X5
- UniProtKB/TrEMBL
-
B7Z4H4
-
XM_054359435.1 → XP_054215410.1 membrane-associated guanylate kinase, WW and PDZ domain-containing protein 2 isoform X1
- UniProtKB/TrEMBL
-
B7Z4H4
-
XM_054359446.1 → XP_054215421.1 membrane-associated guanylate kinase, WW and PDZ domain-containing protein 2 isoform X11
- UniProtKB/TrEMBL
-
A0A0D9SEY4
-
XM_054359445.1 → XP_054215420.1 membrane-associated guanylate kinase, WW and PDZ domain-containing protein 2 isoform X11
- UniProtKB/TrEMBL
-
A0A0D9SEY4