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    LIX1L limb and CNS expressed 1 like [ Homo sapiens (human) ]

    Gene ID: 128077, updated on 27-Nov-2024

    Summary

    Official Symbol
    LIX1Lprovided by HGNC
    Official Full Name
    limb and CNS expressed 1 likeprovided by HGNC
    Primary source
    HGNC:HGNC:28715
    See related
    Ensembl:ENSG00000271601 AllianceGenome:HGNC:28715
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Homo sapiens
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
    Summary
    Predicted to be involved in autophagosome maturation. Predicted to be active in cytoplasm. [provided by Alliance of Genome Resources, Nov 2024]
    Expression
    Ubiquitous expression in ovary (RPKM 17.6), endometrium (RPKM 13.1) and 24 other tissues See more
    Orthologs
    NEW
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    Genomic context

    See LIX1L in Genome Data Viewer
    Location:
    1q21.1
    Exon count:
    6
    Annotation release Status Assembly Chr Location
    RS_2024_08 current GRCh38.p14 (GCF_000001405.40) 1 NC_000001.11 (145933423..145958017, complement)
    RS_2024_08 current T2T-CHM13v2.0 (GCF_009914755.1) 1 NC_060925.1 (145050242..145074834, complement)
    RS_2024_09 previous assembly GRCh37.p13 (GCF_000001405.25) 1 NC_000001.10 (145477069..145501670)

    Chromosome 1 - NC_000001.11Genomic Context describing neighboring genes Neighboring gene peroxisomal biogenesis factor 11 beta Neighboring gene H3K4me1 hESC enhancer GRCh37_chr1:145516673-145517219 Neighboring gene H3K27ac-H3K4me1 hESC enhancer GRCh37_chr1:145516125-145516672 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 1616 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 1617 Neighboring gene gonadotropin releasing hormone receptor 2 (pseudogene) Neighboring gene MED14-independent group 3 enhancer GRCh37_chr1:145507474-145508673 Neighboring gene RNA binding motif protein 8A Neighboring gene LIX1L antisense RNA 1 Neighboring gene ATAC-STARR-seq lymphoblastoid silent region 1269 Neighboring gene ATAC-STARR-seq lymphoblastoid silent region 1270 Neighboring gene conserved acetylation island sequence C12 enhancer Neighboring gene H3K4me1 hESC enhancer GRCh37_chr1:145473321-145474156 Neighboring gene ankyrin repeat domain 34A Neighboring gene Sharpr-MPRA regulatory region 4010 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 1621 Neighboring gene RNA polymerase III subunit GL Neighboring gene H3K4me1 hESC enhancer GRCh37_chr1:145458517-145459016 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 1622 Neighboring gene BRD4-independent group 4 enhancer GRCh37_chr1:145455010-145456209

    Genomic regions, transcripts, and products

    Expression

    • Project title: HPA RNA-seq normal tissues
    • Description: RNA-seq was performed of tissue samples from 95 human individuals representing 27 different tissues in order to determine tissue-specificity of all protein-coding genes
    • BioProject: PRJEB4337
    • Publication: PMID 24309898
    • Analysis date: Wed Apr 4 07:08:55 2018

    Interactions

    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

    Markers

    Clone Names

    • MGC46719, DKFZp762F237

    Gene Ontology Provided by GOA

    Process Evidence Code Pubs
    involved_in autophagosome maturation IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    Component Evidence Code Pubs
    is_active_in cytoplasm IBA
    Inferred from Biological aspect of Ancestor
    more info
     

    General protein information

    Preferred Names
    LIX1-like protein
    Names
    Lix1 homolog-like

    NCBI Reference Sequences (RefSeq)

    NEW Try the new Transcript table

    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_153713.3NP_714924.1  LIX1-like protein

      See identical proteins and their annotated locations for NP_714924.1

      Status: VALIDATED

      Source sequence(s)
      AC243547, AK128733, BC035727
      Consensus CDS
      CCDS72873.1
      UniProtKB/Swiss-Prot
      Q6AI36, Q8IVB5
      UniProtKB/TrEMBL
      B3KY58
      Related
      ENSP00000474487.3, ENST00000604000.4
      Conserved Domains (1) summary
      pfam14954
      Location:87328
      LIX1; Limb expression 1

    RefSeqs of Annotated Genomes: GCF_000001405.40-RS_2024_08

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCh38.p14 Primary Assembly

    Genomic

    1. NC_000001.11 Reference GRCh38.p14 Primary Assembly

      Range
      145933423..145958017 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    Alternate T2T-CHM13v2.0

    Genomic

    1. NC_060925.1 Alternate T2T-CHM13v2.0

      Range
      145050242..145074834 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)