NEW
Try the new Transcript table
These reference sequences exist independently of genome builds. Explain
These reference sequences are curated independently of the genome
annotation cycle, so their versions may not match the RefSeq versions in the current
genome build. Identify version mismatches by comparing the version of the RefSeq in
this section to the one reported in Genomic regions,
transcripts, and products above.
Genomic
-
NG_011756.2 RefSeqGene
- Range
-
96106..469535
- Download
- GenBank, FASTA, Sequence Viewer (Graphics), LRG_872
mRNA and Protein(s)
-
NM_015180.6 → NP_055995.4 nesprin-2 isoform 1
See identical proteins and their annotated locations for NP_055995.4
Status: REVIEWED
- Description
- Transcript Variant: This variant (1) lacks an alternate in-frame exon compared to variant 5. The resulting isoform (1) has the same N- and C-termini but is shorter compared to isoform 5.
- Source sequence(s)
-
AF435011, AF495911, AI685725, AL355094, DB271849
- Consensus CDS
-
CCDS41963.1
- UniProtKB/Swiss-Prot
- B4DND7, B4DPR6, I6XXQ5, Q540G1, Q86YP9, Q8N1S3, Q8NF49, Q8TER7, Q8WWW3, Q8WWW4, Q8WWW5, Q8WXH0, Q8WXH1, Q9UFQ4, Q9Y2L4, Q9Y4R1
- UniProtKB/TrEMBL
-
G3V5X4
- Related
- ENSP00000341781.4, ENST00000344113.8
- Conserved Domains (7) summary
-
- COG0419
Location:3298 → 3912
- SbcC; DNA repair exonuclease SbcCD ATPase subunit [Replication, recombination and repair]
- PRK03918
Location:1868 → 2417
- PRK03918; chromosome segregation protein; Provisional
- cd00014
Location:33 → 135
- CH; Calponin homology domain; actin-binding domain which may be present as a single copy or in tandem repeats (which increases binding affinity). The CH domain is found in cytoskeletal and signal transduction proteins, including actin-binding proteins like ...
- cd00176
Location:6137 → 6350
- SPEC; Spectrin repeats, found in several proteins involved in cytoskeletal structure; family members include spectrin, alpha-actinin and dystrophin; the spectrin repeat forms a three helix bundle with the second helix interrupted by proline in some sequences; ...
- pfam00307
Location:182 → 281
- CH; Calponin homology (CH) domain
- pfam10541
Location:6854 → 6885
- KASH; Nuclear envelope localization domain
- cl02488
Location:5178 → 5384
- SPEC; Spectrin repeats, found in several proteins involved in cytoskeletal structure; family members include spectrin, alpha-actinin and dystrophin; the spectrin repeat forms a three helix bundle with the second helix interrupted by proline in some sequences; ...
-
NM_182910.2 → NP_878914.1 nesprin-2 isoform 2
See identical proteins and their annotated locations for NP_878914.1
Status: REVIEWED
- Description
- Transcript Variant: This variant (2) differs in the 5' UTR and coding sequence compared to variant 5. The resulting isoform (2) is shorter at the N-terminus compared to isoform 5.
- Source sequence(s)
-
AI685725, AY184204
- UniProtKB/Swiss-Prot
-
Q8WXH0
- Related
-
ENST00000441438.2
- Conserved Domains (2) summary
-
- cd00176
Location:84 → 307
- SPEC; Spectrin repeats, found in several proteins involved in cytoskeletal structure; family members include spectrin, alpha-actinin and dystrophin; the spectrin repeat forms a three helix bundle with the second helix interrupted by proline in some sequences; ...
- pfam10541
Location:398 → 429
- KASH; Nuclear envelope localization domain
-
NM_182913.4 → NP_878917.1 nesprin-2 isoform 4
See identical proteins and their annotated locations for NP_878917.1
Status: REVIEWED
- Description
- Transcript Variant: This variant (4) differs in the 5' UTR and coding sequence compared to variant 5. The resulting isoform (4) is shorter at the N-terminus compared to isoform 5.
- Source sequence(s)
-
AI685725, AL355094, AY061758
- Consensus CDS
-
CCDS45124.1
- UniProtKB/Swiss-Prot
-
Q8WXH0
- Related
- ENSP00000391937.2, ENST00000458046.6
- Conserved Domains (2) summary
-
- cd00176
Location:210 → 433
- SPEC; Spectrin repeats, found in several proteins involved in cytoskeletal structure; family members include spectrin, alpha-actinin and dystrophin; the spectrin repeat forms a three helix bundle with the second helix interrupted by proline in some sequences; ...
- pfam10541
Location:525 → 556
- KASH; Nuclear envelope localization domain
-
NM_182914.3 → NP_878918.2 nesprin-2 isoform 5
Status: REVIEWED
- Description
- Transcript Variant: This variant (5) represents the longest transcript and encodes the longest isoform (5).
- Source sequence(s)
-
AL162832, AL355094, AL359235
- Consensus CDS
-
CCDS9761.2
- UniProtKB/TrEMBL
-
G3V5X4
- Related
- ENSP00000450831.2, ENST00000555002.6
- Conserved Domains (7) summary
-
- COG0419
Location:3298 → 3912
- SbcC; DNA repair exonuclease SbcCD ATPase subunit [Replication, recombination and repair]
- PRK03918
Location:1868 → 2417
- PRK03918; chromosome segregation protein; Provisional
- cd00014
Location:33 → 135
- CH; Calponin homology domain; actin-binding domain which may be present as a single copy or in tandem repeats (which increases binding affinity). The CH domain is found in cytoskeletal and signal transduction proteins, including actin-binding proteins like ...
- cd00176
Location:6137 → 6350
- SPEC; Spectrin repeats, found in several proteins involved in cytoskeletal structure; family members include spectrin, alpha-actinin and dystrophin; the spectrin repeat forms a three helix bundle with the second helix interrupted by proline in some sequences; ...
- pfam00307
Location:182 → 281
- CH; Calponin homology (CH) domain
- pfam10541
Location:6876 → 6907
- KASH; Nuclear envelope localization domain
- cl02488
Location:5178 → 5384
- SPEC; Spectrin repeats, found in several proteins involved in cytoskeletal structure; family members include spectrin, alpha-actinin and dystrophin; the spectrin repeat forms a three helix bundle with the second helix interrupted by proline in some sequences; ...
The following sections contain reference sequences that belong to a
specific genome build. Explain
This section includes genomic Reference
Sequences (RefSeqs) from all assemblies on which this gene is annotated, such as
RefSeqs for chromosomes and scaffolds (contigs) from both reference and alternate
assemblies. Model RNAs and proteins are also reported here.
Reference GRCh38.p14 Primary Assembly
Genomic
-
NC_000014.9 Reference GRCh38.p14 Primary Assembly
- Range
-
63761596..64226449
- Download
- GenBank, FASTA, Sequence Viewer (Graphics)
mRNA and Protein(s)
-
XM_047431152.1 → XP_047287108.1 nesprin-2 isoform X1
- UniProtKB/TrEMBL
-
G3V5X4
-
XM_011536576.3 → XP_011534878.1 nesprin-2 isoform X1
See identical proteins and their annotated locations for XP_011534878.1
- UniProtKB/TrEMBL
-
G3V5X4
- Conserved Domains (7) summary
-
- COG0419
Location:3298 → 3912
- SbcC; DNA repair exonuclease SbcCD ATPase subunit [Replication, recombination and repair]
- PRK03918
Location:1868 → 2369
- PRK03918; chromosome segregation protein; Provisional
- cd00014
Location:33 → 135
- CH; Calponin homology domain; actin-binding domain which may be present as a single copy or in tandem repeats (which increases binding affinity). The CH domain is found in cytoskeletal and signal transduction proteins, including actin-binding proteins like ...
- cd00176
Location:6137 → 6350
- SPEC; Spectrin repeats, found in several proteins involved in cytoskeletal structure; family members include spectrin, alpha-actinin and dystrophin; the spectrin repeat forms a three helix bundle with the second helix interrupted by proline in some sequences; ...
- pfam00307
Location:182 → 281
- CH; Calponin homology (CH) domain
- pfam10541
Location:6905 → 6936
- KASH; Nuclear envelope localization domain
- cl02488
Location:5178 → 5384
- SPEC; Spectrin repeats, found in several proteins involved in cytoskeletal structure; family members include spectrin, alpha-actinin and dystrophin; the spectrin repeat forms a three helix bundle with the second helix interrupted by proline in some sequences; ...
-
XM_047431149.1 → XP_047287105.1 nesprin-2 isoform X1
- UniProtKB/TrEMBL
-
G3V5X4
-
XM_011536574.2 → XP_011534876.1 nesprin-2 isoform X1
See identical proteins and their annotated locations for XP_011534876.1
- UniProtKB/TrEMBL
-
G3V5X4
- Conserved Domains (7) summary
-
- COG0419
Location:3298 → 3912
- SbcC; DNA repair exonuclease SbcCD ATPase subunit [Replication, recombination and repair]
- PRK03918
Location:1868 → 2369
- PRK03918; chromosome segregation protein; Provisional
- cd00014
Location:33 → 135
- CH; Calponin homology domain; actin-binding domain which may be present as a single copy or in tandem repeats (which increases binding affinity). The CH domain is found in cytoskeletal and signal transduction proteins, including actin-binding proteins like ...
- cd00176
Location:6137 → 6350
- SPEC; Spectrin repeats, found in several proteins involved in cytoskeletal structure; family members include spectrin, alpha-actinin and dystrophin; the spectrin repeat forms a three helix bundle with the second helix interrupted by proline in some sequences; ...
- pfam00307
Location:182 → 281
- CH; Calponin homology (CH) domain
- pfam10541
Location:6905 → 6936
- KASH; Nuclear envelope localization domain
- cl02488
Location:5178 → 5384
- SPEC; Spectrin repeats, found in several proteins involved in cytoskeletal structure; family members include spectrin, alpha-actinin and dystrophin; the spectrin repeat forms a three helix bundle with the second helix interrupted by proline in some sequences; ...
-
XM_011536578.2 → XP_011534880.1 nesprin-2 isoform X2
- UniProtKB/TrEMBL
-
G3V5X4
- Conserved Domains (7) summary
-
- COG0419
Location:3298 → 3912
- SbcC; DNA repair exonuclease SbcCD ATPase subunit [Replication, recombination and repair]
- PRK03918
Location:1868 → 2369
- PRK03918; chromosome segregation protein; Provisional
- cd00014
Location:33 → 135
- CH; Calponin homology domain; actin-binding domain which may be present as a single copy or in tandem repeats (which increases binding affinity). The CH domain is found in cytoskeletal and signal transduction proteins, including actin-binding proteins like ...
- cd00176
Location:6137 → 6350
- SPEC; Spectrin repeats, found in several proteins involved in cytoskeletal structure; family members include spectrin, alpha-actinin and dystrophin; the spectrin repeat forms a three helix bundle with the second helix interrupted by proline in some sequences; ...
- pfam00307
Location:182 → 281
- CH; Calponin homology (CH) domain
- pfam10541
Location:6904 → 6935
- KASH; Nuclear envelope localization domain
- cl02488
Location:5178 → 5384
- SPEC; Spectrin repeats, found in several proteins involved in cytoskeletal structure; family members include spectrin, alpha-actinin and dystrophin; the spectrin repeat forms a three helix bundle with the second helix interrupted by proline in some sequences; ...
-
XM_011536579.2 → XP_011534881.1 nesprin-2 isoform X3
- UniProtKB/TrEMBL
-
G3V5X4
- Conserved Domains (7) summary
-
- COG0419
Location:3298 → 3912
- SbcC; DNA repair exonuclease SbcCD ATPase subunit [Replication, recombination and repair]
- PRK03918
Location:1868 → 2369
- PRK03918; chromosome segregation protein; Provisional
- cd00014
Location:33 → 135
- CH; Calponin homology domain; actin-binding domain which may be present as a single copy or in tandem repeats (which increases binding affinity). The CH domain is found in cytoskeletal and signal transduction proteins, including actin-binding proteins like ...
- cd00176
Location:6137 → 6350
- SPEC; Spectrin repeats, found in several proteins involved in cytoskeletal structure; family members include spectrin, alpha-actinin and dystrophin; the spectrin repeat forms a three helix bundle with the second helix interrupted by proline in some sequences; ...
- pfam00307
Location:182 → 281
- CH; Calponin homology (CH) domain
- pfam10541
Location:6891 → 6922
- KASH; Nuclear envelope localization domain
- cl02488
Location:5178 → 5384
- SPEC; Spectrin repeats, found in several proteins involved in cytoskeletal structure; family members include spectrin, alpha-actinin and dystrophin; the spectrin repeat forms a three helix bundle with the second helix interrupted by proline in some sequences; ...
-
XM_011536580.3 → XP_011534882.1 nesprin-2 isoform X6
- UniProtKB/TrEMBL
-
G3V5X4
- Conserved Domains (7) summary
-
- COG0419
Location:3298 → 3912
- SbcC; DNA repair exonuclease SbcCD ATPase subunit [Replication, recombination and repair]
- PRK03918
Location:1868 → 2369
- PRK03918; chromosome segregation protein; Provisional
- cd00014
Location:33 → 135
- CH; Calponin homology domain; actin-binding domain which may be present as a single copy or in tandem repeats (which increases binding affinity). The CH domain is found in cytoskeletal and signal transduction proteins, including actin-binding proteins like ...
- cd00176
Location:6137 → 6350
- SPEC; Spectrin repeats, found in several proteins involved in cytoskeletal structure; family members include spectrin, alpha-actinin and dystrophin; the spectrin repeat forms a three helix bundle with the second helix interrupted by proline in some sequences; ...
- pfam00307
Location:182 → 281
- CH; Calponin homology (CH) domain
- pfam10541
Location:6890 → 6921
- KASH; Nuclear envelope localization domain
- cl02488
Location:5178 → 5384
- SPEC; Spectrin repeats, found in several proteins involved in cytoskeletal structure; family members include spectrin, alpha-actinin and dystrophin; the spectrin repeat forms a three helix bundle with the second helix interrupted by proline in some sequences; ...
-
XM_005267454.2 → XP_005267511.1 nesprin-2 isoform X4
- UniProtKB/TrEMBL
-
G3V5X4
- Conserved Domains (7) summary
-
- COG0419
Location:3298 → 3912
- SbcC; DNA repair exonuclease SbcCD ATPase subunit [Replication, recombination and repair]
- PRK03918
Location:1868 → 2417
- PRK03918; chromosome segregation protein; Provisional
- cd00014
Location:33 → 135
- CH; Calponin homology domain; actin-binding domain which may be present as a single copy or in tandem repeats (which increases binding affinity). The CH domain is found in cytoskeletal and signal transduction proteins, including actin-binding proteins like ...
- cd00176
Location:6137 → 6350
- SPEC; Spectrin repeats, found in several proteins involved in cytoskeletal structure; family members include spectrin, alpha-actinin and dystrophin; the spectrin repeat forms a three helix bundle with the second helix interrupted by proline in some sequences; ...
- pfam00307
Location:182 → 281
- CH; Calponin homology (CH) domain
- pfam10541
Location:6891 → 6922
- KASH; Nuclear envelope localization domain
- cl02488
Location:5178 → 5384
- SPEC; Spectrin repeats, found in several proteins involved in cytoskeletal structure; family members include spectrin, alpha-actinin and dystrophin; the spectrin repeat forms a three helix bundle with the second helix interrupted by proline in some sequences; ...
-
XM_005267456.2 → XP_005267513.1 nesprin-2 isoform X5
- UniProtKB/TrEMBL
-
G3V5X4
- Conserved Domains (7) summary
-
- COG0419
Location:3298 → 3912
- SbcC; DNA repair exonuclease SbcCD ATPase subunit [Replication, recombination and repair]
- PRK03918
Location:1868 → 2417
- PRK03918; chromosome segregation protein; Provisional
- cd00014
Location:33 → 135
- CH; Calponin homology domain; actin-binding domain which may be present as a single copy or in tandem repeats (which increases binding affinity). The CH domain is found in cytoskeletal and signal transduction proteins, including actin-binding proteins like ...
- cd00176
Location:6137 → 6350
- SPEC; Spectrin repeats, found in several proteins involved in cytoskeletal structure; family members include spectrin, alpha-actinin and dystrophin; the spectrin repeat forms a three helix bundle with the second helix interrupted by proline in some sequences; ...
- pfam00307
Location:182 → 281
- CH; Calponin homology (CH) domain
- pfam10541
Location:6890 → 6921
- KASH; Nuclear envelope localization domain
- cl02488
Location:5178 → 5384
- SPEC; Spectrin repeats, found in several proteins involved in cytoskeletal structure; family members include spectrin, alpha-actinin and dystrophin; the spectrin repeat forms a three helix bundle with the second helix interrupted by proline in some sequences; ...
-
XM_005267457.2 → XP_005267514.1 nesprin-2 isoform X9
- UniProtKB/TrEMBL
-
G3V5X4
- Conserved Domains (7) summary
-
- COG0419
Location:3298 → 3912
- SbcC; DNA repair exonuclease SbcCD ATPase subunit [Replication, recombination and repair]
- PRK03918
Location:1868 → 2417
- PRK03918; chromosome segregation protein; Provisional
- cd00014
Location:33 → 135
- CH; Calponin homology domain; actin-binding domain which may be present as a single copy or in tandem repeats (which increases binding affinity). The CH domain is found in cytoskeletal and signal transduction proteins, including actin-binding proteins like ...
- cd00176
Location:6137 → 6350
- SPEC; Spectrin repeats, found in several proteins involved in cytoskeletal structure; family members include spectrin, alpha-actinin and dystrophin; the spectrin repeat forms a three helix bundle with the second helix interrupted by proline in some sequences; ...
- pfam00307
Location:182 → 281
- CH; Calponin homology (CH) domain
- pfam10541
Location:6877 → 6908
- KASH; Nuclear envelope localization domain
- cl02488
Location:5178 → 5384
- SPEC; Spectrin repeats, found in several proteins involved in cytoskeletal structure; family members include spectrin, alpha-actinin and dystrophin; the spectrin repeat forms a three helix bundle with the second helix interrupted by proline in some sequences; ...
-
XM_011536581.2 → XP_011534883.1 nesprin-2 isoform X7
- UniProtKB/TrEMBL
-
G3V5X4
- Conserved Domains (7) summary
-
- COG0419
Location:3298 → 3912
- SbcC; DNA repair exonuclease SbcCD ATPase subunit [Replication, recombination and repair]
- PRK03918
Location:1868 → 2369
- PRK03918; chromosome segregation protein; Provisional
- cd00014
Location:33 → 135
- CH; Calponin homology domain; actin-binding domain which may be present as a single copy or in tandem repeats (which increases binding affinity). The CH domain is found in cytoskeletal and signal transduction proteins, including actin-binding proteins like ...
- cd00176
Location:6137 → 6350
- SPEC; Spectrin repeats, found in several proteins involved in cytoskeletal structure; family members include spectrin, alpha-actinin and dystrophin; the spectrin repeat forms a three helix bundle with the second helix interrupted by proline in some sequences; ...
- pfam00307
Location:182 → 281
- CH; Calponin homology (CH) domain
- pfam10541
Location:6882 → 6913
- KASH; Nuclear envelope localization domain
- cl02488
Location:5178 → 5384
- SPEC; Spectrin repeats, found in several proteins involved in cytoskeletal structure; family members include spectrin, alpha-actinin and dystrophin; the spectrin repeat forms a three helix bundle with the second helix interrupted by proline in some sequences; ...
-
XM_047431153.1 → XP_047287109.1 nesprin-2 isoform X8
- UniProtKB/TrEMBL
-
G3V5X4
-
XM_047431154.1 → XP_047287110.1 nesprin-2 isoform X11
- UniProtKB/TrEMBL
-
G3V5X4
-
XM_047431156.1 → XP_047287112.1 nesprin-2 isoform X13
- UniProtKB/TrEMBL
-
G3V5X4
-
XM_005267458.2 → XP_005267515.1 nesprin-2 isoform X10
- UniProtKB/TrEMBL
-
G3V5X4
- Conserved Domains (7) summary
-
- COG0419
Location:3298 → 3912
- SbcC; DNA repair exonuclease SbcCD ATPase subunit [Replication, recombination and repair]
- PRK03918
Location:1868 → 2369
- PRK03918; chromosome segregation protein; Provisional
- cd00014
Location:33 → 135
- CH; Calponin homology domain; actin-binding domain which may be present as a single copy or in tandem repeats (which increases binding affinity). The CH domain is found in cytoskeletal and signal transduction proteins, including actin-binding proteins like ...
- cd00176
Location:6137 → 6350
- SPEC; Spectrin repeats, found in several proteins involved in cytoskeletal structure; family members include spectrin, alpha-actinin and dystrophin; the spectrin repeat forms a three helix bundle with the second helix interrupted by proline in some sequences; ...
- pfam00307
Location:182 → 281
- CH; Calponin homology (CH) domain
- pfam10541
Location:6868 → 6899
- KASH; Nuclear envelope localization domain
- cl02488
Location:5178 → 5384
- SPEC; Spectrin repeats, found in several proteins involved in cytoskeletal structure; family members include spectrin, alpha-actinin and dystrophin; the spectrin repeat forms a three helix bundle with the second helix interrupted by proline in some sequences; ...
-
XM_047431155.1 → XP_047287111.1 nesprin-2 isoform X12
- UniProtKB/TrEMBL
-
G3V5X4
-
XM_005267459.2 → XP_005267516.1 nesprin-2 isoform X15
- UniProtKB/TrEMBL
-
G3V5X4
- Conserved Domains (7) summary
-
- COG0419
Location:3298 → 3912
- SbcC; DNA repair exonuclease SbcCD ATPase subunit [Replication, recombination and repair]
- PRK03918
Location:1868 → 2417
- PRK03918; chromosome segregation protein; Provisional
- cd00014
Location:33 → 135
- CH; Calponin homology domain; actin-binding domain which may be present as a single copy or in tandem repeats (which increases binding affinity). The CH domain is found in cytoskeletal and signal transduction proteins, including actin-binding proteins like ...
- cd00176
Location:6137 → 6350
- SPEC; Spectrin repeats, found in several proteins involved in cytoskeletal structure; family members include spectrin, alpha-actinin and dystrophin; the spectrin repeat forms a three helix bundle with the second helix interrupted by proline in some sequences; ...
- pfam00307
Location:182 → 281
- CH; Calponin homology (CH) domain
- pfam10541
Location:6853 → 6884
- KASH; Nuclear envelope localization domain
- cl02488
Location:5178 → 5384
- SPEC; Spectrin repeats, found in several proteins involved in cytoskeletal structure; family members include spectrin, alpha-actinin and dystrophin; the spectrin repeat forms a three helix bundle with the second helix interrupted by proline in some sequences; ...
-
XM_011536582.2 → XP_011534884.1 nesprin-2 isoform X14
- UniProtKB/TrEMBL
-
G3V5X4
- Conserved Domains (7) summary
-
- COG0419
Location:3298 → 3912
- SbcC; DNA repair exonuclease SbcCD ATPase subunit [Replication, recombination and repair]
- PRK03918
Location:1868 → 2417
- PRK03918; chromosome segregation protein; Provisional
- cd00014
Location:33 → 135
- CH; Calponin homology domain; actin-binding domain which may be present as a single copy or in tandem repeats (which increases binding affinity). The CH domain is found in cytoskeletal and signal transduction proteins, including actin-binding proteins like ...
- cd00176
Location:6098 → 6311
- SPEC; Spectrin repeats, found in several proteins involved in cytoskeletal structure; family members include spectrin, alpha-actinin and dystrophin; the spectrin repeat forms a three helix bundle with the second helix interrupted by proline in some sequences; ...
- pfam00307
Location:182 → 281
- CH; Calponin homology (CH) domain
- pfam10541
Location:6866 → 6897
- KASH; Nuclear envelope localization domain
- cl02488
Location:5139 → 5345
- SPEC; Spectrin repeats, found in several proteins involved in cytoskeletal structure; family members include spectrin, alpha-actinin and dystrophin; the spectrin repeat forms a three helix bundle with the second helix interrupted by proline in some sequences; ...
-
XM_047431157.1 → XP_047287113.1 nesprin-2 isoform X16
- UniProtKB/TrEMBL
-
G3V5X4
-
XM_047431158.1 → XP_047287114.1 nesprin-2 isoform X17
- UniProtKB/TrEMBL
-
G3V5X4
-
XM_011536577.3 → XP_011534879.1 nesprin-2 isoform X1
See identical proteins and their annotated locations for XP_011534879.1
- UniProtKB/TrEMBL
-
G3V5X4
- Conserved Domains (7) summary
-
- COG0419
Location:3298 → 3912
- SbcC; DNA repair exonuclease SbcCD ATPase subunit [Replication, recombination and repair]
- PRK03918
Location:1868 → 2369
- PRK03918; chromosome segregation protein; Provisional
- cd00014
Location:33 → 135
- CH; Calponin homology domain; actin-binding domain which may be present as a single copy or in tandem repeats (which increases binding affinity). The CH domain is found in cytoskeletal and signal transduction proteins, including actin-binding proteins like ...
- cd00176
Location:6137 → 6350
- SPEC; Spectrin repeats, found in several proteins involved in cytoskeletal structure; family members include spectrin, alpha-actinin and dystrophin; the spectrin repeat forms a three helix bundle with the second helix interrupted by proline in some sequences; ...
- pfam00307
Location:182 → 281
- CH; Calponin homology (CH) domain
- pfam10541
Location:6905 → 6936
- KASH; Nuclear envelope localization domain
- cl02488
Location:5178 → 5384
- SPEC; Spectrin repeats, found in several proteins involved in cytoskeletal structure; family members include spectrin, alpha-actinin and dystrophin; the spectrin repeat forms a three helix bundle with the second helix interrupted by proline in some sequences; ...
-
XM_047431159.1 → XP_047287115.1 nesprin-2 isoform X18
-
XM_011536584.3 → XP_011534886.1 nesprin-2 isoform X19
- Conserved Domains (5) summary
-
- COG1196
Location:2873 → 3746
- Smc; Chromosome segregation ATPase [Cell cycle control, cell division, chromosome partitioning]
- cd00014
Location:33 → 135
- CH; Calponin homology domain; actin-binding domain which may be present as a single copy or in tandem repeats (which increases binding affinity). The CH domain is found in cytoskeletal and signal transduction proteins, including actin-binding proteins like ...
- TIGR02168
Location:1898 → 2639
- SMC_prok_B; chromosome segregation protein SMC, common bacterial type
- pfam00307
Location:182 → 281
- CH; Calponin homology (CH) domain
- cl02488
Location:1840 → 2031
- SPEC; Spectrin repeats, found in several proteins involved in cytoskeletal structure; family members include spectrin, alpha-actinin and dystrophin; the spectrin repeat forms a three helix bundle with the second helix interrupted by proline in some sequences; ...
-
XM_047431151.1 → XP_047287107.1 nesprin-2 isoform X1
- UniProtKB/TrEMBL
-
G3V5X4
-
XM_047431150.1 → XP_047287106.1 nesprin-2 isoform X1
- UniProtKB/TrEMBL
-
G3V5X4
-
XM_011536575.3 → XP_011534877.1 nesprin-2 isoform X1
See identical proteins and their annotated locations for XP_011534877.1
- UniProtKB/TrEMBL
-
G3V5X4
- Conserved Domains (7) summary
-
- COG0419
Location:3298 → 3912
- SbcC; DNA repair exonuclease SbcCD ATPase subunit [Replication, recombination and repair]
- PRK03918
Location:1868 → 2369
- PRK03918; chromosome segregation protein; Provisional
- cd00014
Location:33 → 135
- CH; Calponin homology domain; actin-binding domain which may be present as a single copy or in tandem repeats (which increases binding affinity). The CH domain is found in cytoskeletal and signal transduction proteins, including actin-binding proteins like ...
- cd00176
Location:6137 → 6350
- SPEC; Spectrin repeats, found in several proteins involved in cytoskeletal structure; family members include spectrin, alpha-actinin and dystrophin; the spectrin repeat forms a three helix bundle with the second helix interrupted by proline in some sequences; ...
- pfam00307
Location:182 → 281
- CH; Calponin homology (CH) domain
- pfam10541
Location:6905 → 6936
- KASH; Nuclear envelope localization domain
- cl02488
Location:5178 → 5384
- SPEC; Spectrin repeats, found in several proteins involved in cytoskeletal structure; family members include spectrin, alpha-actinin and dystrophin; the spectrin repeat forms a three helix bundle with the second helix interrupted by proline in some sequences; ...
-
XM_017021101.2 → XP_016876590.1 nesprin-2 isoform X1
- UniProtKB/TrEMBL
-
G3V5X4
- Conserved Domains (7) summary
-
- COG0419
Location:3298 → 3912
- SbcC; DNA repair exonuclease SbcCD ATPase subunit [Replication, recombination and repair]
- PRK03918
Location:1868 → 2369
- PRK03918; chromosome segregation protein; Provisional
- cd00014
Location:33 → 135
- CH; Calponin homology domain; actin-binding domain which may be present as a single copy or in tandem repeats (which increases binding affinity). The CH domain is found in cytoskeletal and signal transduction proteins, including actin-binding proteins like ...
- cd00176
Location:6137 → 6350
- SPEC; Spectrin repeats, found in several proteins involved in cytoskeletal structure; family members include spectrin, alpha-actinin and dystrophin; the spectrin repeat forms a three helix bundle with the second helix interrupted by proline in some sequences; ...
- pfam00307
Location:182 → 281
- CH; Calponin homology (CH) domain
- pfam10541
Location:6905 → 6936
- KASH; Nuclear envelope localization domain
- cl02488
Location:5178 → 5384
- SPEC; Spectrin repeats, found in several proteins involved in cytoskeletal structure; family members include spectrin, alpha-actinin and dystrophin; the spectrin repeat forms a three helix bundle with the second helix interrupted by proline in some sequences; ...
-
XM_047431160.1 → XP_047287116.1 nesprin-2 isoform X20
- Related
-
ENST00000394768.6
-
XM_017021103.3 → XP_016876592.1 nesprin-2 isoform X21
- UniProtKB/TrEMBL
-
Q6MZP0
-
XM_017021104.3 → XP_016876593.1 nesprin-2 isoform X22
- UniProtKB/TrEMBL
-
Q6MZP0
-
XM_047431161.1 → XP_047287117.1 nesprin-2 isoform X23
- UniProtKB/TrEMBL
-
Q6MZP0
- Related
-
ENST00000555022.5
Alternate T2T-CHM13v2.0
Genomic
-
NC_060938.1 Alternate T2T-CHM13v2.0
- Range
-
57969282..58434164
- Download
- GenBank, FASTA, Sequence Viewer (Graphics)
mRNA and Protein(s)
-
XM_054375667.1 → XP_054231642.1 nesprin-2 isoform X1
- UniProtKB/TrEMBL
-
G3V5X4
-
XM_054375672.1 → XP_054231647.1 nesprin-2 isoform X1
- UniProtKB/TrEMBL
-
G3V5X4
-
XM_054375669.1 → XP_054231644.1 nesprin-2 isoform X1
- UniProtKB/TrEMBL
-
G3V5X4
-
XM_054375666.1 → XP_054231641.1 nesprin-2 isoform X1
- UniProtKB/TrEMBL
-
G3V5X4
-
XM_054375674.1 → XP_054231649.1 nesprin-2 isoform X2
- UniProtKB/TrEMBL
-
G3V5X4
-
XM_054375675.1 → XP_054231650.1 nesprin-2 isoform X3
- UniProtKB/TrEMBL
-
G3V5X4
-
XM_054375678.1 → XP_054231653.1 nesprin-2 isoform X6
- UniProtKB/TrEMBL
-
G3V5X4
-
XM_054375676.1 → XP_054231651.1 nesprin-2 isoform X4
- UniProtKB/TrEMBL
-
G3V5X4
-
XM_054375677.1 → XP_054231652.1 nesprin-2 isoform X5
- UniProtKB/TrEMBL
-
G3V5X4
-
XM_054375681.1 → XP_054231656.1 nesprin-2 isoform X9
- UniProtKB/TrEMBL
-
G3V5X4
-
XM_054375679.1 → XP_054231654.1 nesprin-2 isoform X7
- UniProtKB/TrEMBL
-
G3V5X4
-
XM_054375680.1 → XP_054231655.1 nesprin-2 isoform X8
- UniProtKB/TrEMBL
-
G3V5X4
-
XM_054375683.1 → XP_054231658.1 nesprin-2 isoform X11
- UniProtKB/TrEMBL
-
G3V5X4
-
XM_054375685.1 → XP_054231660.1 nesprin-2 isoform X13
- UniProtKB/TrEMBL
-
G3V5X4
-
XM_054375682.1 → XP_054231657.1 nesprin-2 isoform X10
- UniProtKB/TrEMBL
-
G3V5X4
-
XM_054375684.1 → XP_054231659.1 nesprin-2 isoform X12
- UniProtKB/TrEMBL
-
G3V5X4
-
XM_054375687.1 → XP_054231662.1 nesprin-2 isoform X15
- UniProtKB/TrEMBL
-
G3V5X4
-
XM_054375686.1 → XP_054231661.1 nesprin-2 isoform X14
- UniProtKB/TrEMBL
-
G3V5X4
-
XM_054375688.1 → XP_054231663.1 nesprin-2 isoform X16
- UniProtKB/TrEMBL
-
G3V5X4
-
XM_054375689.1 → XP_054231664.1 nesprin-2 isoform X17
- UniProtKB/TrEMBL
-
G3V5X4
-
XM_054375690.1 → XP_054231665.1 nesprin-2 isoform X18
-
XM_054375673.1 → XP_054231648.1 nesprin-2 isoform X1
- UniProtKB/TrEMBL
-
G3V5X4
-
XM_054375671.1 → XP_054231646.1 nesprin-2 isoform X1
- UniProtKB/TrEMBL
-
G3V5X4
-
XM_054375668.1 → XP_054231643.1 nesprin-2 isoform X1
- UniProtKB/TrEMBL
-
G3V5X4
-
XM_054375670.1 → XP_054231645.1 nesprin-2 isoform X1
- UniProtKB/TrEMBL
-
G3V5X4
-
XM_054375691.1 → XP_054231666.1 nesprin-2 isoform X24
- UniProtKB/TrEMBL
-
A0A0C4DGK3
-
XM_054375692.1 → XP_054231667.1 nesprin-2 isoform X20
-
XM_054375693.1 → XP_054231668.1 nesprin-2 isoform X21
- UniProtKB/TrEMBL
-
Q6MZP0
-
XM_054375694.1 → XP_054231669.1 nesprin-2 isoform X22
- UniProtKB/TrEMBL
-
Q6MZP0
-
XM_054375695.1 → XP_054231670.1 nesprin-2 isoform X23
- UniProtKB/TrEMBL
-
Q6MZP0
The following Reference Sequences have been suppressed. Explain
These RefSeqs were suppressed for the
cited reason(s). Suppressed RefSeqs do not appear in BLAST databases, related
sequence links, or BLAST links (BLink), but may still be retrieved by clicking on
their accession.version below.
-
NM_182912.1: Suppressed sequence
- Description
- NM_182912.1: This RefSeq was permanently suppressed because currently there is insufficient support for the transcript and the protein.