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    LINC00869 long intergenic non-protein coding RNA 869 [ Homo sapiens (human) ]

    Gene ID: 57234, updated on 10-Dec-2024

    Summary

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    Official Symbol
    LINC00869provided by HGNC
    Official Full Name
    long intergenic non-protein coding RNA 869provided by HGNC
    Primary source
    HGNC:HGNC:29050
    See related
    Ensembl:ENSG00000291158 AllianceGenome:HGNC:29050
    Gene type
    ncRNA
    RefSeq status
    VALIDATED
    Organism
    Homo sapiens
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
    Also known as
    FAM91A2
    Expression
    Ubiquitous expression in spleen (RPKM 3.2), lymph node (RPKM 3.0) and 25 other tissues See more
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    Genomic context

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    See LINC00869 in Genome Data Viewer
    Location:
    1q21.2
    Exon count:
    10
    Annotation release Status Assembly Chr Location
    RS_2024_08 current GRCh38.p14 (GCF_000001405.40) 1 NC_000001.11 (149607012..149679523)
    RS_2024_08 current T2T-CHM13v2.0 (GCF_009914755.1) 1 NC_060925.1 (148731162..148803659)
    RS_2024_09 previous assembly GRCh37.p13 (GCF_000001405.25) 1 NC_000001.10 (149576161..149651107)

    Chromosome 1 - NC_000001.11Genomic Context describing neighboring genes Neighboring gene uncharacterized LOC101060227 Neighboring gene tRNA-Asn (anticodon GTT) 25-1 Neighboring gene uncharacterized LOC124904410 Neighboring gene peptidylprolyl isomerase A like 4C Neighboring gene uncharacterized LOC124904409 Neighboring gene NANOG-H3K27ac-H3K4me1 hESC enhancer GRCh37_chr1:147931672-147932203 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 1652 Neighboring gene RNA, variant U1 small nuclear 30 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr1:144301087-144301742 Neighboring gene protein FAM91A1-like Neighboring gene H3K4me1 hESC enhancer GRCh37_chr1:149287863-149288485 Neighboring gene RNA, U1 small nuclear 68, pseudogene Neighboring gene uncharacterized LOC644634

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Expression

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    • Project title: HPA RNA-seq normal tissues
    • Description: RNA-seq was performed of tissue samples from 95 human individuals representing 27 different tissues in order to determine tissue-specificity of all protein-coding genes
    • BioProject: PRJEB4337
    • Publication: PMID 24309898
    • Analysis date: Wed Apr 4 07:08:55 2018

    Bibliography

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    Related articles in PubMed

    1. LINC00869 Promotes Hepatocellular Carcinoma Metastasis via Protrusion Formation. Shao X, et al. Mol Cancer Res, 2024 Mar 1. PMID 37934195
    2. Characterization of cDNA clones in size-fractionated cDNA libraries from human brain. Seki N, et al. DNA Res, 1997 Oct 31. PMID 9455484
    3. Diversification of transcriptional modulation: large-scale identification and characterization of putative alternative promoters of human genes. Kimura K, et al. Genome Res, 2006 Jan. PMID 16344560, Free PMC Article
    4. Complete sequencing and characterization of 21,243 full-length human cDNAs. Ota T, et al. Nat Genet, 2004 Jan. PMID 14702039
    5. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. Strausberg RL, et al. Proc Natl Acad Sci U S A, 2002 Dec 24. PMID 12477932, Free PMC Article

    See all (6) citations in PubMed

    GeneRIFs: Gene References Into Functions

    What's a GeneRIF?
    1. LINC00869 Promotes Hepatocellular Carcinoma Metastasis via Protrusion Formation.
      Title: LINC00869 Promotes Hepatocellular Carcinoma Metastasis via Protrusion Formation.
    Submit: New GeneRIF Correction

    Phenotypes

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    Review eQTL and phenotype association data in this region using PheGenI

    Variation

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    See variants in ClinVar

    See studies and variants in dbVar

    See Variation Viewer (GRCh37.p13)

    See Variation Viewer (GRCh38)

    General gene information

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    Other Names

    • family with sequence similarity 91, member A2

    Clone Names

    • FLJ97060, FLJ99375, KIAA0493

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    RNA

    1. NR_111950.1 RNA Sequence

      Status: VALIDATED

      Description
      Transcript Variant: This variant (6) currently represents the longest transcript.
      Source sequence(s)
      AB007962, AC242842, CB217586
      Related
      ENST00000610578.4

    2. NR_111951.1 RNA Sequence

      Status: VALIDATED

      Description
      Transcript Variant: This variant (7) lacks multiple 3' exons and contains an alternate 3' exon structure, resulting in a shorter transcript, compared to variant 6.
      Source sequence(s)
      AC242842, AC243772
      Related
      ENST00000778182.1

    3. NR_111952.1 RNA Sequence

      Status: VALIDATED

      Description
      Transcript Variant: This variant (8) lacks multiple 3' exons and contains an alternate 3' exon structure, resulting in a shorter transcript, compared to variant 6.
      Source sequence(s)
      AC242842, AC243772

    4. NR_111953.1 RNA Sequence

      Status: VALIDATED

      Description
      Transcript Variant: This variant (9) lacks multiple 3' exons and contains an alternate 3' exon structure, resulting in a shorter transcript, compared to variant 6.
      Source sequence(s)
      AC242842, AC243772, BU602007
      Related
      ENST00000778181.1

    RefSeqs of Annotated Genomes: GCF_000001405.40-RS_2024_08

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCh38.p14 Primary Assembly

    Genomic

    1. NC_000001.11 Reference GRCh38.p14 Primary Assembly

      Range
      149607012..149679523
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    Alternate T2T-CHM13v2.0

    Genomic

    1. NC_060925.1 Alternate T2T-CHM13v2.0

      Range
      148731162..148803659
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    Suppressed Reference Sequence(s)

    The following Reference Sequences have been suppressed. Explain

    1. NR_046135.1: Suppressed sequence

      Description
      NR_046135.1: This RefSeq was permanently suppressed because currently there is insufficient support for the transcript.

    2. NR_046136.1: Suppressed sequence

      Description
      NR_046136.1: This RefSeq was permanently suppressed because currently there is insufficient support for the transcript.

    3. NR_046137.1: Suppressed sequence

      Description
      NR_046137.1: This RefSeq was permanently suppressed because currently there is insufficient support for the transcript.

    4. NR_046138.1: Suppressed sequence

      Description
      NR_046138.1: This RefSeq was permanently suppressed because currently there is insufficient support for the transcript.

    5. NR_046139.1: Suppressed sequence

      Description
      NR_046139.1: This RefSeq was permanently suppressed because currently there is insufficient support for the transcript.
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    P0C866.1 GenPept UniProtKB/Swiss-Prot:P0C866

    Gene LinkOut

    The following LinkOut resources are supplied by external providers. These providers are responsible for maintaining the links.