Protein interactions
Protein |
Gene |
Interaction |
Pubs |
Nef
|
nef
|
Genome-wide shRNA screening identifies GGA2, which is required for HIV-1 Nef-induced downregulation of CD4 in HeLa CD4+ cells |
PubMed
|
Pr55(Gag)
|
gag
|
siRNA-mediated depletion of GGA2 leads to a significant increase in particle release in an HIV-1 Gag late domain-dependent manner, while GGA2 overexpression severely reduces virus particle production by impairing Gag trafficking to the membrane |
PubMed
|
Vpr
|
vpr
|
Expression of a patient-derived HIV-1 Vpr protein reveals a significant reduction in Vpr nuclear import. Vpr F72L mutation is responsible for this decreased Vpr nuclear import and the F72L mutant is co-localized with gamma-adaptin in the Golgi apparatus |
PubMed
|
Go to the HIV-1, Human Interaction Database