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    FRK1 FLG22-induced receptor-like kinase 1 [ Arabidopsis thaliana (thale cress) ]

    Gene ID: 816436, updated on 18-Sep-2024

    Summary

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    Official Symbol
    FRK1
    Official Full Name
    FLG22-induced receptor-like kinase 1
    Primary source
    TAIR:AT2G19190
    Locus tag
    AT2G19190
    See related
    Araport:AT2G19190
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Arabidopsis thaliana (ecotype: Columbia)
    Lineage
    Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta; Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis
    Also known as
    FLG22-induced receptor-like kinase 1; T20K24.21; T20K24_21
    Summary
    Receptor-like protein kinase. Involved in early defense signaling.
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    Genomic context

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    See FRK1 in Genome Data Viewer
    Location:
    chromosome: 2
    Exon count:
    13
    Sequence:
    Chromosome: 2; NC_003071.7 (8326049..8329944, complement)

    Chromosome 2 - NC_003071.7Genomic Context describing neighboring genes Neighboring gene Pectin lyase-like superfamily protein Neighboring gene Core-2/I-branching beta-1,6-N-acetylglucosaminyltransferase family protein Neighboring gene subtilisin-like serine protease 3 Neighboring gene uncharacterized protein Neighboring gene ncRNA Neighboring gene miscRNA

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_003071.7

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. A re-elicitation assay to correlate flg22-signaling competency with ligand-induced endocytic degradation of the FLS2 receptor. Leslie ME, et al. Methods Mol Biol, 2014. PMID 25117282
    2. Submergence confers immunity mediated by the WRKY22 transcription factor in Arabidopsis. Hsu FC, et al. Plant Cell, 2013 Jul. PMID 23897923, Free PMC Article
    3. Specific bacterial suppressors of MAMP signaling upstream of MAPKKK in Arabidopsis innate immunity. He P, et al. Cell, 2006 May 5. PMID 16678099
    4. A membrane protein/signaling protein interaction network for Arabidopsis version AMPv2. Lalonde S, et al. Front Physiol, 2010. PMID 21423366, Free PMC Article
    5. An extracellular network of Arabidopsis leucine-rich repeat receptor kinases. Smakowska-Luzan E, et al. Nature, 2018 Jan 18. PMID 29320478, Free PMC Article

    See all (8) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    NM_127476.2

    Gene Ontology Provided by TAIR

    Function Evidence Code Pubs
    enables kinase activity ISS
    Inferred from Sequence or Structural Similarity
    more info
    		  
    enables protein binding IPI
    Inferred from Physical Interaction
    more info
    		 PubMed 
    Process Evidence Code Pubs
    acts_upstream_of_or_within defense response to bacterium IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in extracellular region ISM
    Inferred from Sequence Model
    more info
    		  

    General protein information

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    Preferred Names
    FLG22-induced receptor-like kinase 1
    NP_179509.1
    • FLG22-induced receptor-like kinase 1 (FRK1); FUNCTIONS IN: kinase activity; INVOLVED IN: defense response to bacterium; LOCATED IN: endomembrane system; EXPRESSED IN: stem, sepal, stamen; EXPRESSED DURING: 4 anthesis; CONTAINS InterPro DOMAIN/s: Protein kinase, ATP binding site (InterPro:IPR017441), Serine/threonine-protein kinase domain (InterPro:IPR002290), Leucine-rich repeat (InterPro:IPR001611), Serine/threonine-protein kinase-like domain (InterPro:IPR017442), Protein kinase-like domain (InterPro:IPR011009), Serine/threonine-protein kinase, active site (InterPro:IPR008271), Protein kinase, catalytic domain (InterPro:IPR000719), Tyrosine-protein kinase, catalytic domain (InterPro:IPR020635); BEST Arabidopsis thaliana protein match is: Leucine-rich repeat transmembrane protein kinase protein (TAIR:AT4G29990.1); Has 158999 Blast hits to 129792 proteins in 4951 species: Archae - 135; Bacteria - 15029; Metazoa - 47296; Fungi - 11032; Plants - 64935; Viruses - 473; Other Eukaryotes - 20099 (source: NCBI BLink).

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003071.7 Reference assembly

      Range
      8326049..8329944 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_127476.2 → NP_179509.1  FLG22-induced receptor-like kinase 1 [Arabidopsis thaliana]

      See identical proteins and their annotated locations for NP_179509.1

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      O64483
      UniProtKB/TrEMBL
      A0A5S9WZI5, C0LGK5
      Conserved Domains (4) summary
      smart00221
      Location:576 → 839
      STYKc; Protein kinase; unclassified specificity
      cd14066
      Location:580 → 845
      STKc_IRAK; Catalytic domain of the Serine/Threonine kinases, Interleukin-1 Receptor Associated Kinases and related STKs
      sd00033
      Location:396 → 415
      LRR_RI; leucine-rich repeat [structural motif]
      pfam12819
      Location:33 → 358
      Malectin_like; Carbohydrate-binding protein of the ER
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    O64483.1

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