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    FMO GS-OX2 flavin-monooxygenase glucosinolate S-oxygenase 2 [ Arabidopsis thaliana (thale cress) ]

    Gene ID: 842551, updated on 18-Sep-2024

    Summary

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    Official Symbol
    FMO GS-OX2
    Official Full Name
    flavin-monooxygenase glucosinolate S-oxygenase 2
    Primary source
    TAIR:AT1G62540
    Locus tag
    AT1G62540
    See related
    Araport:AT1G62540
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Arabidopsis thaliana (ecotype: Columbia)
    Lineage
    Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta; Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis
    Also known as
    flavin-monooxygenase glucosinolate S-oxygenase 2; T3P18.10; T3P18_10
    Summary
    belongs to the flavin-monooxygenase (FMO) family, encodes a glucosinolate S-oxygenase that catalyzes the conversion of methylthioalkyl glucosinolates to methylsulfinylalkyl glucosinolates
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    Genomic context

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    See FMO GS-OX2 in Genome Data Viewer
    Location:
    chromosome: 1
    Exon count:
    6
    Sequence:
    Chromosome: 1; NC_003070.9 (23151634..23155728)

    Chromosome 1 - NC_003070.9Genomic Context describing neighboring genes Neighboring gene sulfated surface-like glycoprotein Neighboring gene hypothetical protein (DUF863) Neighboring gene pseudo Neighboring gene miscRNA

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_003070.9

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Subclade of flavin-monooxygenases involved in aliphatic glucosinolate biosynthesis. Li J, et al. Plant Physiol, 2008 Nov. PMID 18799661, Free PMC Article
    2. Sequence and analysis of chromosome 1 of the plant Arabidopsis thaliana. Theologis A, et al. Nature, 2000 Dec 14. PMID 11130712

    GeneRIFs: Gene References Into Functions

    Pathways from PubChem

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    General gene information

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    NM_001334037.1
    NM_104933.3

    Gene Ontology Provided by TAIR

    Function Evidence Code Pubs
    enables 3-methylthiopropyl glucosinolate S-oxygenase activity IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    enables 4-methylthiopropyl glucosinolate S-oxygenase activity IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    enables 4-methylthiopropyl glucosinolate S-oxygenase activity IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    enables 5-methylthiopropyl glucosinolate S-oxygenase activity IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    enables 7-methylthiopropyl glucosinolate S-oxygenase activity IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    enables 8-methylthiopropyl glucosinolate S-oxygenase activity IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    enables 8-methylthiopropyl glucosinolate S-oxygenase activity IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    enables N,N-dimethylaniline monooxygenase activity IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    enables N,N-dimethylaniline monooxygenase activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables NADP binding IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables flavin adenine dinucleotide binding IEA
    Inferred from Electronic Annotation
    more info
    		  
    Process Evidence Code Pubs
    acts_upstream_of_or_within glucosinolate biosynthetic process IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in nucleus ISM
    Inferred from Sequence Model
    more info
    		  

    General protein information

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    Preferred Names
    flavin-monooxygenase glucosinolate S-oxygenase 2
    NP_564796.1
    • flavin-monooxygenase glucosinolate S-oxygenase 2 (FMO GS-OX2); CONTAINS InterPro DOMAIN/s: Flavin-containing monooxygenase FMO (InterPro:IPR000960), Flavin-containing monooxygenase-like (InterPro:IPR020946); BEST Arabidopsis thaliana protein match is: flavin-monooxygenase glucosinolate S-oxygenase 1 (TAIR:AT1G65860.1); Has 12235 Blast hits to 11922 proteins in 1493 species: Archae - 60; Bacteria - 6240; Metazoa - 1058; Fungi - 1528; Plants - 820; Viruses - 0; Other Eukaryotes - 2529 (source: NCBI BLink).

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003070.9 Reference assembly

      Range
      23151634..23155728
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_001334036.1 → NP_001320894.1  flavin-monooxygenase glucosinolate S-oxygenase 2 [Arabidopsis thaliana]

      Status: REVIEWED

      UniProtKB/TrEMBL
      A0A1P8AP83, A0A5S9WRV2

    2. NM_104933.3 → NP_564796.1  flavin-monooxygenase glucosinolate S-oxygenase 2 [Arabidopsis thaliana]

      See identical proteins and their annotated locations for NP_564796.1

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      Q94K43, Q9SXE3
      UniProtKB/TrEMBL
      A0A5S9WRV2
      Conserved Domains (2) summary
      PLN02172
      Location:1 → 457
      PLN02172; flavin-containing monooxygenase FMO GS-OX
      cl21454
      Location:21 → 235
      NADB_Rossmann; Rossmann-fold NAD(P)(+)-binding proteins

    3. NM_001334037.1 → NP_001320895.1  flavin-monooxygenase glucosinolate S-oxygenase 2 [Arabidopsis thaliana]

      Status: REVIEWED

      UniProtKB/TrEMBL
      A0A1P8APF2, A0A5S9WRV2
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q94K43.1

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