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    ZML2 ZIM-LIKE 2 [ Arabidopsis thaliana (thale cress) ]

    Gene ID: 841585, updated on 18-Sep-2024

    Summary

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    Official Symbol
    ZML2
    Official Full Name
    ZIM-LIKE 2
    Primary source
    TAIR:AT1G51600
    Locus tag
    AT1G51600
    See related
    Araport:AT1G51600
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Arabidopsis thaliana (ecotype: Columbia)
    Lineage
    Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta; Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis
    Also known as
    F5D21.22; F5D21_22; GATA TRANSCRIPTION FACTOR 28; GATA28; TIFY2A; ZIM-LIKE 2
    Summary
    member of a novel family of plant-specific GATA-type transcription factors.
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    Genomic context

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    See ZML2 in Genome Data Viewer
    Location:
    chromosome: 1
    Exon count:
    8
    Sequence:
    Chromosome: 1; NC_003070.9 (19132221..19135630)

    Chromosome 1 - NC_003070.9Genomic Context describing neighboring genes Neighboring gene RNA-binding KH domain-containing protein Neighboring gene alpha-mannosidase 1 Neighboring gene ncRNA Neighboring gene Cation efflux family protein Neighboring gene Protein kinase superfamily protein Neighboring gene O-fucosyltransferase family protein

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_003070.9

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. The CRYPTOCHROME1-dependent response to excess light is mediated through the transcriptional activators ZINC FINGER PROTEIN EXPRESSED IN INFLORESCENCE MERISTEM LIKE1 and ZML2 in Arabidopsis. Shaikhali J, et al. Plant Cell, 2012 Jul. PMID 22786870, Free PMC Article
    2. Telomerase Interaction Partners-Insight from Plants. Fulnečková J, et al. Int J Mol Sci, 2021 Dec 29. PMID 35008793, Free PMC Article
    3. Tandem affinity purification of AtTERT reveals putative interaction partners of plant telomerase in vivo. Majerská J, et al. Protoplasma, 2017 Jul. PMID 27853871
    4. Transcriptional Regulation of Arabidopsis Polycomb Repressive Complex 2 Coordinates Cell-Type Proliferation and Differentiation. de Lucas M, et al. Plant Cell, 2016 Oct. PMID 27650334, Free PMC Article
    5. Promoter-based integration in plant defense regulation. Li B, et al. Plant Physiol, 2014 Dec. PMID 25352272, Free PMC Article

    See all (12) citations in PubMed

    GeneRIFs: Gene References Into Functions

    What's a GeneRIF?
    1. The ZML2 and ZML1 GATA transcription factors are two essential components of the cry1-mediated photoprotective response.
      Title: The CRYPTOCHROME1-dependent response to excess light is mediated through the transcriptional activators ZINC FINGER PROTEIN EXPRESSED IN INFLORESCENCE MERISTEM LIKE1 and ZML2 in Arabidopsis.
    Submit: New GeneRIF Correction

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    NM_104038.4
    NM_202273.3

    Gene Ontology Provided by TAIR

    Function Evidence Code Pubs
    enables identical protein binding IPI
    Inferred from Physical Interaction
    more info
    		 PubMed 
    enables protein binding IPI
    Inferred from Physical Interaction
    more info
    		 PubMed 
    enables transcription cis-regulatory region binding IPI
    Inferred from Physical Interaction
    more info
    		 PubMed 
    enables zinc ion binding IEA
    Inferred from Electronic Annotation
    more info
    		  
    Process Evidence Code Pubs
    involved_in regulation of DNA-templated transcription IEA
    Inferred from Electronic Annotation
    more info
    		  
    Component Evidence Code Pubs
    located_in nucleus ISM
    Inferred from Sequence Model
    more info
    		  

    General protein information

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    Preferred Names
    ZIM-LIKE 2
    NP_564593.1
    • ZIM-LIKE 2 (ZML2); FUNCTIONS IN: sequence-specific DNA binding, zinc ion binding, sequence-specific DNA binding transcription factor activity; INVOLVED IN: regulation of transcription, DNA-dependent; EXPRESSED IN: 24 plant structures; EXPRESSED DURING: 14 growth stages; CONTAINS InterPro DOMAIN/s: Tify (InterPro:IPR010399), Zinc finger, GATA-type (InterPro:IPR000679), CCT domain (InterPro:IPR010402); BEST Arabidopsis thaliana protein match is: ZIM-like 1 (TAIR:AT3G21175.1); Has 2012 Blast hits to 2008 proteins in 187 species: Archae - 0; Bacteria - 0; Metazoa - 0; Fungi - 371; Plants - 1601; Viruses - 0; Other Eukaryotes - 40 (source: NCBI BLink).
    NP_974002.1
    • ZIM-LIKE 2 (ZML2); FUNCTIONS IN: sequence-specific DNA binding, sequence-specific DNA binding transcription factor activity, zinc ion binding; INVOLVED IN: regulation of transcription, DNA-dependent; EXPRESSED IN: 24 plant structures; EXPRESSED DURING: 14 growth stages; CONTAINS InterPro DOMAIN/s: Tify (InterPro:IPR010399), Zinc finger, GATA-type (InterPro:IPR000679), CCT domain (InterPro:IPR010402); BEST Arabidopsis thaliana protein match is: ZIM-like 1 (TAIR:AT3G21175.1); Has 35333 Blast hits to 34131 proteins in 2444 species: Archae - 798; Bacteria - 22429; Metazoa - 974; Fungi - 991; Plants - 531; Viruses - 0; Other Eukaryotes - 9610 (source: NCBI BLink).

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003070.9 Reference assembly

      Range
      19132221..19135630
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_104038.4 → NP_564593.1  ZIM-LIKE 2 [Arabidopsis thaliana]

      See identical proteins and their annotated locations for NP_564593.1

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      Q8H1G0, Q94AN8, Q9C541
      UniProtKB/TrEMBL
      A0A178WGN1, A0A654EJ17
      Conserved Domains (3) summary
      cd00202
      Location:222 → 265
      ZnF_GATA; Zinc finger DNA binding domain; binds specifically to DNA consensus sequence [AT]GATA[AG] promoter elements; a subset of family members may also bind protein; zinc-finger consensus topology is C-X(2)-C-X(17)-C-X(2)-C
      pfam06200
      Location:78 → 111
      tify; tify domain
      pfam06203
      Location:147 → 190
      CCT; CCT motif

    2. NM_202273.3 → NP_974002.1  ZIM-LIKE 2 [Arabidopsis thaliana]

      See identical proteins and their annotated locations for NP_974002.1

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      Q8H1G0, Q94AN8, Q9C541
      UniProtKB/TrEMBL
      A0A178WGN1, A0A654EJ17
      Conserved Domains (3) summary
      cd00202
      Location:222 → 265
      ZnF_GATA; Zinc finger DNA binding domain; binds specifically to DNA consensus sequence [AT]GATA[AG] promoter elements; a subset of family members may also bind protein; zinc-finger consensus topology is C-X(2)-C-X(17)-C-X(2)-C
      pfam06200
      Location:78 → 111
      tify; tify domain
      pfam06203
      Location:147 → 190
      CCT; CCT motif
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q8H1G0.1

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