MAP1C methionine aminopeptidase 1B [Arabidopsis thaliana (thale cress)] - Gene

Summary

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Official Symbol: MAP1C
Official Full Name: methionine aminopeptidase 1B
Primary source: TAIR:AT1G13270
Locus tag: AT1G13270
See related: Araport:AT1G13270
Gene type: protein coding
RefSeq status: REVIEWED
Organism: Arabidopsis thaliana (ecotype: Columbia)
Lineage: Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta; Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis
Also known as: MAP1B; methionine aminopeptidase 1B; METHIONINE AMINOPEPTIDASE 1B
Summary: Encodes a methionine aminopeptidase formerly called MAP1B, renamed to MAP1C.
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Genomic context

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See MAP1C in Genome Data Viewer

Location:: chromosome: 1

Exon count:: 9

Sequence:: Chromosome: 1; NC_003070.9 (4544889..4547373)

Chromosome 1 - NC_003070.9 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Go to reference sequence details

Genomic Sequence:: NC_003070.9

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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GeneRIFs: Gene References Into Functions

What's a GeneRIF?

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Interactions

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Products	Interactant	Other Gene	Complex	Source	Pubs	Description

General gene information

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NM_101198.4

Supported by ESTs:

NM_202086.1

Supported by ESTs:

Gene Ontology Provided by TAIR

Function	Evidence Code	Pubs
enables initiator methionyl aminopeptidase activity	IEA Inferred from Electronic Annotation more info
enables mRNA binding	IDA Inferred from Direct Assay more info	PubMed

Process	Evidence Code	Pubs
acts_upstream_of_or_within N-terminal protein amino acid modification	TAS Traceable Author Statement more info	PubMed

Component	Evidence Code	Pubs
located_in chloroplast	HDA more info	PubMed
located_in chloroplast	ISM Inferred from Sequence Model more info
located_in chloroplast	TAS Traceable Author Statement more info	PubMed
located_in extracellular region	HDA more info	PubMed
located_in mitochondrion	TAS Traceable Author Statement more info	PubMed

General protein information

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Preferred Names: methionine aminopeptidase 1B

NP_172785.1

methionine aminopeptidase 1B (MAP1C); FUNCTIONS IN: metalloexopeptidase activity, aminopeptidase activity; INVOLVED IN: proteolysis, N-terminal protein amino acid modification; LOCATED IN: mitochondrion, chloroplast; EXPRESSED IN: 22 plant structures; EXPRESSED DURING: 13 growth stages; CONTAINS InterPro DOMAIN/s: Peptidase M24, structural domain (InterPro:IPR000994), Peptidase M24A, methionine aminopeptidase, subfamily 1 (InterPro:IPR002467), Peptidase M24, methionine aminopeptidase (InterPro:IPR001714); BEST Arabidopsis thaliana protein match is: methionine aminopeptidase 1C (TAIR:AT3G25740.1); Has 18008 Blast hits to 17988 proteins in 2832 species: Archae - 481; Bacteria - 12145; Metazoa - 393; Fungi - 260; Plants - 253; Viruses - 0; Other Eukaryotes - 4476 (source: NCBI BLink).

NP_973815.1

methionine aminopeptidase 1B (MAP1C); FUNCTIONS IN: metalloexopeptidase activity, aminopeptidase activity; INVOLVED IN: proteolysis, N-terminal protein amino acid modification; LOCATED IN: mitochondrion, chloroplast; EXPRESSED IN: 22 plant structures; EXPRESSED DURING: 13 growth stages; CONTAINS InterPro DOMAIN/s: Peptidase M24, structural domain (InterPro:IPR000994), Peptidase M24A, methionine aminopeptidase, subfamily 1 (InterPro:IPR002467), Peptidase M24, methionine aminopeptidase (InterPro:IPR001714); BEST Arabidopsis thaliana protein match is: methionine aminopeptidase 1C (TAIR:AT3G25740.1); Has 35333 Blast hits to 34131 proteins in 2444 species: Archae - 798; Bacteria - 22429; Metazoa - 974; Fungi - 991; Plants - 531; Viruses - 0; Other Eukaryotes - 9610 (source: NCBI BLink).

NCBI Reference Sequences (RefSeq)

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Genome Annotation

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Reference assembly

Genomic

NC_003070.9 Reference assembly

Range

4544889..4547373

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GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

NM_101198.4 → NP_172785.1 methionine aminopeptidase 1B [Arabidopsis thaliana]

See identical proteins and their annotated locations for NP_172785.1

Status: REVIEWED

UniProtKB/Swiss-Prot

Q9FV52, Q9FX70

UniProtKB/TrEMBL

A0A178W4W1

Conserved Domains (1) summary

cd01086
Location:132 → 368

MetAP1; Methionine Aminopeptidase 1. E.C. 3.4.11.18. Also known as methionyl aminopeptidase and Peptidase M. Catalyzes release of N-terminal amino acids, preferentially methionine, from peptides and arylamides.
NM_202086.1 → NP_973815.1 methionine aminopeptidase 1B [Arabidopsis thaliana]

See identical proteins and their annotated locations for NP_973815.1

Status: REVIEWED

UniProtKB/TrEMBL

F4HQQ8

Conserved Domains (1) summary

cl00279
Location:132 → 272

APP_MetAP; A family including aminopeptidase P, aminopeptidase M, and prolidase. Also known as metallopeptidase family M24. This family of enzymes is able to cleave amido-, imido- and amidino-containing bonds. Members exibit relatively narrow substrate specificity ...