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    U11/U12-31K RNA recognition motif and CCHC-type zinc finger domains containing protein [ Arabidopsis thaliana (thale cress) ]

    Gene ID: 820203, updated on 18-Sep-2024

    Summary

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    Official Symbol
    U11/U12-31K
    Official Full Name
    RNA recognition motif and CCHC-type zinc finger domains containing protein
    Primary source
    TAIR:AT3G10400
    Locus tag
    AT3G10400
    See related
    Araport:AT3G10400
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Arabidopsis thaliana (ecotype: Columbia)
    Lineage
    Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta; Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis
    Summary
    Encodes a U12-type spliceosomal protein U11/U12-31K. Involved in U12 intron splicing via RNA chaperone activity and affects plant development.
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    Genomic context

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    See U11/U12-31K in Genome Data Viewer
    Location:
    chromosome: 3
    Exon count:
    1
    Sequence:
    Chromosome: 3; NC_003074.8 (3232608..3233690)

    Chromosome 3 - NC_003074.8Genomic Context describing neighboring genes Neighboring gene subunit of exocyst complex 8 Neighboring gene protein FLOWERING locus D-like protein Neighboring gene vacuolar acid trehalase Neighboring gene SERINE CARBOXYPEPTIDASE-LIKE 49 Neighboring gene tRNA-Tyr

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_003074.8

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. The minor spliceosomal protein U11/U12-31K is an RNA chaperone crucial for U12 intron splicing and the development of dicot and monocot plants. Kwak KJ, et al. PLoS One, 2012. PMID 22912901, Free PMC Article
    2. The Arabidopsis U12-type spliceosomal protein U11/U12-31K is involved in U12 intron splicing via RNA chaperone activity and affects plant development. Kim WY, et al. Plant Cell, 2010 Dec. PMID 21148817, Free PMC Article
    3. Sequence and analysis of chromosome 3 of the plant Arabidopsis thaliana. Salanoubat M, et al. Nature, 2000 Dec 14. PMID 11130713

    GeneRIFs: Gene References Into Functions

    What's a GeneRIF?
    1. Data shows that the U11/U12-31K protein is an indispensible RNA chaperone that functions in U12 intron splicing and for normal development of plants. [U11/U12-31K]
      Title: The minor spliceosomal protein U11/U12-31K is an RNA chaperone crucial for U12 intron splicing and the development of dicot and monocot plants.
    Submit: New GeneRIF Correction

    Pathways from PubChem

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    General gene information

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    Homology

    NM_111875.3

    Gene Ontology Provided by TAIR

    Function Evidence Code Pubs
    enables zinc ion binding IEA
    Inferred from Electronic Annotation
    more info
    		  
    Process Evidence Code Pubs
    acts_upstream_of_or_within developmental process IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    acts_upstream_of_or_within mRNA splicing, via spliceosome IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    acts_upstream_of_or_within regulation of cell division IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    Component Evidence Code Pubs
    part_of U12-type spliceosomal complex IEA
    Inferred from Electronic Annotation
    more info
    		  
    located_in nucleus IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    located_in nucleus ISM
    Inferred from Sequence Model
    more info
    		  

    General protein information

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    Preferred Names
    RNA recognition motif and CCHC-type zinc finger domains containing protein
    NP_187651.1
    • RNA recognition motif and CCHC-type zinc finger domains containing protein; FUNCTIONS IN: RNA binding, nucleotide binding, zinc ion binding, nucleic acid binding; INVOLVED IN: biological_process unknown; LOCATED IN: cellular_component unknown; EXPRESSED IN: 16 plant structures; EXPRESSED DURING: 7 growth stages; CONTAINS InterPro DOMAIN/s: RNA recognition motif, RNP-1 (InterPro:IPR000504), Ribonucleoprotein, BRUNO-like (InterPro:IPR015903), Nucleotide-binding, alpha-beta plait (InterPro:IPR012677), Zinc finger, CCHC-type (InterPro:IPR001878); BEST Arabidopsis thaliana protein match is: ortholog of human splicing factor SC35 (TAIR:AT5G64200.2); Has 867 Blast hits to 867 proteins in 310 species: Archae - 0; Bacteria - 0; Metazoa - 452; Fungi - 160; Plants - 158; Viruses - 0; Other Eukaryotes - 97 (source: NCBI BLink).

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003074.8 Reference assembly

      Range
      3232608..3233690
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_111875.3 → NP_187651.1  RNA recognition motif and CCHC-type zinc finger domains containing protein [Arabidopsis thaliana]

      See identical proteins and their annotated locations for NP_187651.1

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      Q0WQK5, Q9CAE4
      UniProtKB/TrEMBL
      A0A178VAL3, A0A5S9XAT5
      Conserved Domains (2) summary
      PTZ00368
      Location:154 → 173
      PTZ00368; universal minicircle sequence binding protein (UMSBP); Provisional
      cd12393
      Location:56 → 131
      RRM_ZCRB1; RNA recognition motif (RRM) found in Zinc finger CCHC-type and RNA-binding motif-containing protein 1 (ZCRB1) and similar proteins
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q9CAE4.1

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