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    GFAT putative glucosamine-fructose-6-phosphate aminotransferase [ Arabidopsis thaliana (thale cress) ]

    Gene ID: 821995, updated on 18-Sep-2024

    Summary

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    Official Symbol
    GFAT
    Official Full Name
    putative glucosamine-fructose-6-phosphate aminotransferase
    Primary source
    TAIR:AT3G24090
    Locus tag
    AT3G24090
    See related
    Araport:AT3G24090
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Arabidopsis thaliana (ecotype: Columbia)
    Lineage
    Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta; Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis
    Also known as
    L-glutamine D-fructose-6-phosphate amidotransferase
    Summary
    Encodes a glutamine-fructose-6-phosphate transaminase that likely plays a role in UDP-N-acetylglucosamine biosynthesis.
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    Genomic context

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    See GFAT in Genome Data Viewer
    Location:
    chromosome: 3
    Exon count:
    10
    Sequence:
    Chromosome: 3; NC_003074.8 (8697685..8701052, complement)

    Chromosome 3 - NC_003074.8Genomic Context describing neighboring genes Neighboring gene Zinc knuckle (CCHC-type) family protein Neighboring gene KRR1 family protein Neighboring gene Paired amphipathic helix (PAH2) superfamily protein Neighboring gene Uncharacterized protein family SERF Neighboring gene Calcium-binding EF-hand family protein

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_003074.8

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Deficiency of AtGFAT1 activity impairs growth, pollen germination and tolerance to tunicamycin in Arabidopsis. Vu KV, et al. J Exp Bot, 2019 Mar 27. PMID 30775776, Free PMC Article
    2. Sequence and analysis of chromosome 3 of the plant Arabidopsis thaliana. Salanoubat M, et al. Nature, 2000 Dec 14. PMID 11130713

    GeneRIFs: Gene References Into Functions

    General gene information

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    Homology

    NM_113314.4

    Gene Ontology Provided by TAIR

    Function Evidence Code Pubs
    enables carbohydrate derivative binding IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables glutamine-fructose-6-phosphate transaminase (isomerizing) activity IDA
    Inferred from Direct Assay
    more info
    		  
    enables glutamine-fructose-6-phosphate transaminase (isomerizing) activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    Process Evidence Code Pubs
    involved_in UDP-N-acetylglucosamine biosynthetic process IEA
    Inferred from Electronic Annotation
    more info
    		  
    involved_in UDP-N-acetylglucosamine metabolic process IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    acts_upstream_of_or_within glucosamine biosynthetic process IDA
    Inferred from Direct Assay
    more info
    		  
    involved_in glutamine metabolic process IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    involved_in pollen wall assembly IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    involved_in protein N-linked glycosylation IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    involved_in response to dithiothreitol IEP
    Inferred from Expression Pattern
    more info
    		 PubMed 
    involved_in response to endoplasmic reticulum stress IEP
    Inferred from Expression Pattern
    more info
    		 PubMed 
    involved_in response to endoplasmic reticulum stress IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in cytoplasm ISM
    Inferred from Sequence Model
    more info
    		  

    General protein information

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    Preferred Names
    putative glucosamine-fructose-6-phosphate aminotransferase
    NP_189051.3
    • glutamine-fructose-6-phosphate transaminase (isomerizing)s;sugar binding;transaminases; FUNCTIONS IN: sugar binding, transaminase activity, glutamine-fructose-6-phosphate transaminase (isomerizing) activity; INVOLVED IN: carbohydrate biosynthetic process, carbohydrate metabolic process, metabolic process; LOCATED IN: cytoplasm; EXPRESSED IN: 20 plant structures; EXPRESSED DURING: 12 growth stages; CONTAINS InterPro DOMAIN/s: Glutamine amidotransferase, class-II (InterPro:IPR000583), Sugar isomerase (SIS) (InterPro:IPR001347), Glucosamine-fructose-6-phosphate aminotransferase, isomerising (InterPro:IPR005855), Glutamine amidotransferase, type II (InterPro:IPR017932); Has 19000 Blast hits to 18984 proteins in 2800 species: Archae - 500; Bacteria - 10467; Metazoa - 411; Fungi - 223; Plants - 106; Viruses - 14; Other Eukaryotes - 7279 (source: NCBI BLink).

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003074.8 Reference assembly

      Range
      8697685..8701052 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_113314.4 → NP_189051.3  putative glucosamine-fructose-6-phosphate aminotransferase [Arabidopsis thaliana]

      See identical proteins and their annotated locations for NP_189051.3

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      A0A178V979, Q9LIP9
      UniProtKB/TrEMBL
      A0A384L621
      Conserved Domains (1) summary
      PLN02981
      Location:1 → 677
      PLN02981; glucosamine:fructose-6-phosphate aminotransferase
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q9LIP9.1

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