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    SCL30A SC35-like splicing factor 30A [ Arabidopsis thaliana (thale cress) ]

    Gene ID: 820559, updated on 18-Sep-2024

    Summary

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    Official Symbol
    SCL30A
    Official Full Name
    SC35-like splicing factor 30A
    Primary source
    TAIR:AT3G13570
    Locus tag
    AT3G13570
    See related
    Araport:AT3G13570
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Arabidopsis thaliana (ecotype: Columbia)
    Lineage
    Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta; Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis
    Also known as
    At-SCL30A; SC35-like splicing factor 30A
    Summary
    encodes an SC35-like splicing factor of 30 kD that is localized to the nuclear specks. Barta et al (2010) have proposed a nomenclature for Serine/Arginine-Rich Protein Splicing Factors (SR proteins): Plant Cell. 2010, 22:2926.
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    Genomic context

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    See SCL30A in Genome Data Viewer
    Location:
    chromosome: 3
    Exon count:
    6
    Sequence:
    Chromosome: 3; NC_003074.8 (4429256..4432159, complement)

    Chromosome 3 - NC_003074.8Genomic Context describing neighboring genes Neighboring gene Ubiquitin-conjugating enzyme family protein Neighboring gene O-Glycosyl hydrolases family 17 protein Neighboring gene Ribosomal protein L30/L7 family protein Neighboring gene Cysteine/Histidine-rich C1 domain family protein

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_003074.8

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. The SCL30a SR protein regulates ABA-dependent seed traits and germination under stress. Laloum T, et al. Plant Cell Environ, 2023 Jul. PMID 37098235
    2. Identification of an intronic splicing regulatory element involved in auto-regulation of alternative splicing of SCL33 pre-mRNA. Thomas J, et al. Plant J, 2012 Dec. PMID 22913769
    3. Dynamic nucleocytoplasmic shuttling of an Arabidopsis SR splicing factor: role of the RNA-binding domains. Rausin G, et al. Plant Physiol, 2010 May. PMID 20237019, Free PMC Article
    4. Co-localisation studies of Arabidopsis SR splicing factors reveal different types of speckles in plant cell nuclei. Lorković ZJ, et al. Exp Cell Res, 2008 Oct 15. PMID 18674533
    5. Network of interactions of a novel plant-specific Arg/Ser-rich protein, atRSZ33, with atSC35-like splicing factors. Lopato S, et al. J Biol Chem, 2002 Oct 18. PMID 12176998

    See all (14) citations in PubMed

    GeneRIFs: Gene References Into Functions

    What's a GeneRIF?
    1. The SCL30a SR protein regulates ABA-dependent seed traits and germination under stress.
      Title: The SCL30a SR protein regulates ABA-dependent seed traits and germination under stress.
    Submit: New GeneRIF Correction

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    NM_112203.4

    Gene Ontology Provided by TAIR

    Function Evidence Code Pubs
    enables mRNA binding HDA PubMed 
    enables mRNA binding IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    enables protein binding IPI
    Inferred from Physical Interaction
    more info
    		 PubMed 
    Process Evidence Code Pubs
    acts_upstream_of_or_within RNA splicing NAS
    Non-traceable Author Statement
    more info
    		 PubMed 
    acts_upstream_of_or_within mRNA splicing, via spliceosome IGI
    Inferred from Genetic Interaction
    more info
    		 PubMed 
    acts_upstream_of_or_within mRNA splicing, via spliceosome TAS
    Traceable Author Statement
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in cytosol HDA PubMed 
    located_in nuclear speck IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    located_in nucleus ISM
    Inferred from Sequence Model
    more info
    		  

    General protein information

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    Preferred Names
    SC35-like splicing factor 30A
    NP_187966.1
    • SC35-like splicing factor 30A (SCL30A); FUNCTIONS IN: RNA binding, nucleotide binding, nucleic acid binding; INVOLVED IN: nuclear mRNA splicing, via spliceosome, RNA splicing; LOCATED IN: nuclear speck; EXPRESSED IN: 26 plant structures; EXPRESSED DURING: 14 growth stages; CONTAINS InterPro DOMAIN/s: RNA recognition motif, RNP-1 (InterPro:IPR000504), Nucleotide-binding, alpha-beta plait (InterPro:IPR012677); BEST Arabidopsis thaliana protein match is: SC35-like splicing factor 33 (TAIR:AT1G55310.3); Has 39411 Blast hits to 22154 proteins in 1003 species: Archae - 84; Bacteria - 1991; Metazoa - 19033; Fungi - 3968; Plants - 4828; Viruses - 731; Other Eukaryotes - 8776 (source: NCBI BLink).

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003074.8 Reference assembly

      Range
      4429256..4432159 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_112203.4 → NP_187966.1  SC35-like splicing factor 30A [Arabidopsis thaliana]

      See identical proteins and their annotated locations for NP_187966.1

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      Q9FYA8, Q9LHP2
      UniProtKB/TrEMBL
      A0A178VJ91, A0A5S9XBT6, A0A654F8H6
      Conserved Domains (3) summary
      COG0724
      Location:36 → 225
      RRM; RNA recognition motif (RRM) domain [Translation, ribosomal structure and biogenesis]
      pfam10446
      Location:196 → 262
      DUF2457; Protein of unknown function (DUF2457)
      cl17169
      Location:37 → 120
      RRM_SF; RNA recognition motif (RRM) superfamily
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q9LHP2.1

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