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    EBS3 Alg9-like mannosyltransferase family [ Arabidopsis thaliana (thale cress) ]

    Gene ID: 838261, updated on 18-Sep-2024

    Summary

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    Official Symbol
    EBS3
    Official Full Name
    Alg9-like mannosyltransferase family
    Primary source
    TAIR:AT1G16900
    Locus tag
    AT1G16900
    See related
    Araport:AT1G16900
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Arabidopsis thaliana (ecotype: Columbia)
    Lineage
    Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta; Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis
    Also known as
    EMS-mutagenized bri1 suppressor 3; F17F16.20
    Summary
    Encodes the Arabidopsis ortholog of the yeast/human ALG9 catalyzing the luminal addition of two alpha-1,2 Man residues in assembling Glc3Man9GlcNAc2.
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    Genomic context

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    See EBS3 in Genome Data Viewer
    Location:
    chromosome: 1
    Exon count:
    10
    Sequence:
    Chromosome: 1; NC_003070.9 (5779008..5782433, complement)

    Chromosome 1 - NC_003070.9Genomic Context describing neighboring genes Neighboring gene uridylyltransferase-like protein Neighboring gene ubiquitin-conjugating enzyme 36 Neighboring gene ncRNA Neighboring gene Curculin-like (mannose-binding) lectin family protein Neighboring gene LIGHT-DEPENDENT SHORT HYPOCOTYLS-like protein (DUF640)

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_003070.9

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Mutations of an alpha1,6 mannosyltransferase inhibit endoplasmic reticulum-associated degradation of defective brassinosteroid receptors in Arabidopsis. Hong Z, et al. Plant Cell, 2009 Dec. PMID 20023196, Free PMC Article
    2. Evolutionarily conserved glycan signal to degrade aberrant brassinosteroid receptors in Arabidopsis. Hong Z, et al. Proc Natl Acad Sci U S A, 2012 Jul 10. PMID 22733738, Free PMC Article
    3. Putative glycosyltransferases and other plant Golgi apparatus proteins are revealed by LOPIT proteomics. Nikolovski N, et al. Plant Physiol, 2012 Oct. PMID 22923678, Free PMC Article
    4. Evidence for network evolution in an Arabidopsis interactome map. Arabidopsis Interactome Mapping Consortium. Science, 2011 Jul 29. PMID 21798944, Free PMC Article
    5. Sequence and analysis of chromosome 1 of the plant Arabidopsis thaliana. Theologis A, et al. Nature, 2000 Dec 14. PMID 11130712

    GeneRIFs: Gene References Into Functions

    Pathways from PubChem

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    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Homology

    NM_101551.4

    Gene Ontology Provided by TAIR

    Function Evidence Code Pubs
    enables GDP-Man:Man3GlcNAc2-PP-Dol alpha-1,2-mannosyltransferase activity NAS
    Non-traceable Author Statement
    more info
    		 PubMed 
    enables alpha-1,2-mannosyltransferase activity IGI
    Inferred from Genetic Interaction
    more info
    		 PubMed 
    enables dol-P-Man:Man(6)GlcNAc(2)-PP-Dol alpha-1,2-mannosyltransferase activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables dol-P-Man:Man(8)GlcNAc(2)-PP-Dol alpha-1,2-mannosyltransferase activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables glycosyltransferase activity ISS
    Inferred from Sequence or Structural Similarity
    more info
    		  
    Process Evidence Code Pubs
    acts_upstream_of_or_within ERAD pathway IGI
    Inferred from Genetic Interaction
    more info
    		 PubMed 
    involved_in dolichol-linked oligosaccharide biosynthetic process NAS
    Non-traceable Author Statement
    more info
    		 PubMed 
    involved_in protein glycosylation IEA
    Inferred from Electronic Annotation
    more info
    		  
    Component Evidence Code Pubs
    located_in endoplasmic reticulum HDA PubMed 

    General protein information

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    Preferred Names
    Alg9-like mannosyltransferase family
    NP_173134.2
    • Alg9-like mannosyltransferase family; FUNCTIONS IN: sugar binding, transferase activity, transferring glycosyl groups; INVOLVED IN: GPI anchor biosynthetic process; LOCATED IN: intrinsic to endoplasmic reticulum membrane; EXPRESSED IN: 22 plant structures; EXPRESSED DURING: 14 growth stages; CONTAINS InterPro DOMAIN/s: Alg9-like mannosyltransferase (InterPro:IPR005599); BEST Arabidopsis thaliana protein match is: Alg9-like mannosyltransferase family (TAIR:AT5G14850.2); Has 817 Blast hits to 803 proteins in 193 species: Archae - 0; Bacteria - 22; Metazoa - 302; Fungi - 301; Plants - 91; Viruses - 0; Other Eukaryotes - 101 (source: NCBI BLink).

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003070.9 Reference assembly

      Range
      5779008..5782433 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_101551.4 → NP_173134.2  Alg9-like mannosyltransferase family [Arabidopsis thaliana]

      See identical proteins and their annotated locations for NP_173134.2

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      Q9FZ49
      UniProtKB/TrEMBL
      A0A178W2J0, A0A654EAJ3, W8QPA0
      Conserved Domains (1) summary
      pfam03901
      Location:48 → 451
      Glyco_transf_22; Alg9-like mannosyltransferase family
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q9FZ49.1

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