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    ZIFL1 zinc induced facilitator-like 1 [ Arabidopsis thaliana (thale cress) ]

    Gene ID: 831220, updated on 18-Sep-2024

    Summary

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    Official Symbol
    ZIFL1
    Official Full Name
    zinc induced facilitator-like 1
    Primary source
    TAIR:AT5G13750
    Locus tag
    AT5G13750
    See related
    Araport:AT5G13750
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Arabidopsis thaliana (ecotype: Columbia)
    Lineage
    Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta; Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis
    Also known as
    MXE10.2; MXE10_2; zinc induced facilitator-like 1
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    Genomic context

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    See ZIFL1 in Genome Data Viewer
    Location:
    chromosome: 5
    Exon count:
    16
    Sequence:
    Chromosome: 5; NC_003076.8 (4437804..4441701)

    Chromosome 5 - NC_003076.8Genomic Context describing neighboring genes Neighboring gene Uncharacterized protein family (UPF0114) Neighboring gene sigma factor 4 Neighboring gene zinc induced facilitator 1 Neighboring gene Plasma-membrane choline transporter family protein Neighboring gene Pentatricopeptide repeat (PPR-like) superfamily protein Neighboring gene Acyl-CoA N-acyltransferases (NAT) superfamily protein

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_003076.8

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. A major facilitator superfamily transporter plays a dual role in polar auxin transport and drought stress tolerance in Arabidopsis. Remy E, et al. Plant Cell, 2013 Mar. PMID 23524662, Free PMC Article
    2. Functional overlap of two major facilitator superfamily transporter, ZIF1, and ZIFL1 in zinc and iron homeostasis. Lee S, et al. Biochem Biophys Res Commun, 2021 Jun 30. PMID 33964505
    3. Sequence and analysis of chromosome 5 of the plant Arabidopsis thaliana. Tabata S, et al. Nature, 2000 Dec 14. PMID 11130714

    GeneRIFs: Gene References Into Functions

    What's a GeneRIF?
    1. Functional overlap of two major facilitator superfamily transporter, ZIF1, and ZIFL1 in zinc and iron homeostasis.
      Title: Functional overlap of two major facilitator superfamily transporter, ZIF1, and ZIFL1 in zinc and iron homeostasis.
    2. ZIFL1.1 modulates polar auxin transport in the Arabidopsis root.
      Title: A major facilitator superfamily transporter plays a dual role in polar auxin transport and drought stress tolerance in Arabidopsis.
    Submit: New GeneRIF Correction

    General gene information

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    NM_001036800.2
    NM_001343292.1
    NM_121378.5
    NM_180705.3

    Gene Ontology Provided by TAIR

    Function Evidence Code Pubs
    enables solute:potassium antiporter activity IGI
    Inferred from Genetic Interaction
    more info
    		 PubMed 
    Process Evidence Code Pubs
    acts_upstream_of_or_within basipetal auxin transport IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    acts_upstream_of_or_within gravitropism IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    acts_upstream_of_or_within regulation of stomatal closure IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    acts_upstream_of_or_within response to water deprivation IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    acts_upstream_of_or_within root development IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in plant-type vacuole membrane IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    located_in plasma membrane IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    located_in plasma membrane ISM
    Inferred from Sequence Model
    more info
    		  

    General protein information

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    Preferred Names
    zinc induced facilitator-like 1
    NP_001318556.1
    • zinc induced facilitator-like 1 (ZIFL1); FUNCTIONS IN: tetracycline:hydrogen antiporter activity; INVOLVED IN: response to karrikin; LOCATED IN: integral to membrane; EXPRESSED IN: 24 plant structures; EXPRESSED DURING: 15 growth stages; CONTAINS InterPro DOMAIN/s: Major facilitator superfamily (InterPro:IPR020846), Tetracycline resistance protein, TetA (InterPro:IPR001958), Major facilitator superfamily MFS-1 (InterPro:IPR011701), Major facilitator superfamily, general substrate transporter (InterPro:IPR016196); BEST Arabidopsis thaliana protein match is: zinc induced facilitator 1 (TAIR:AT5G13740.1); Has 18147 Blast hits to 17729 proteins in 2581 species: Archae - 337; Bacteria - 13496; Metazoa - 505; Fungi - 2137; Plants - 360; Viruses - 0; Other Eukaryotes - 1312 (source: NCBI BLink).
    NP_568290.3
    • zinc induced facilitator-like 1 (ZIFL1); FUNCTIONS IN: tetracycline:hydrogen antiporter activity; INVOLVED IN: response to karrikin; LOCATED IN: integral to membrane; EXPRESSED IN: 24 plant structures; EXPRESSED DURING: 15 growth stages; CONTAINS InterPro DOMAIN/s: Major facilitator superfamily (InterPro:IPR020846), Tetracycline resistance protein, TetA (InterPro:IPR001958), Major facilitator superfamily MFS-1 (InterPro:IPR011701), Major facilitator superfamily, general substrate transporter (InterPro:IPR016196); BEST Arabidopsis thaliana protein match is: zinc induced facilitator 1 (TAIR:AT5G13740.1); Has 14029 Blast hits to 13852 proteins in 2396 species: Archae - 230; Bacteria - 10365; Metazoa - 433; Fungi - 1573; Plants - 330; Viruses - 0; Other Eukaryotes - 1098 (source: NCBI BLink).
    NP_851036.1
    • zinc induced facilitator-like 1 (ZIFL1); FUNCTIONS IN: tetracycline:hydrogen antiporter activity; INVOLVED IN: response to karrikin; LOCATED IN: integral to membrane; EXPRESSED IN: 24 plant structures; EXPRESSED DURING: 15 growth stages; CONTAINS InterPro DOMAIN/s: Major facilitator superfamily (InterPro:IPR020846), Tetracycline resistance protein, TetA (InterPro:IPR001958), Major facilitator superfamily MFS-1 (InterPro:IPR011701), Major facilitator superfamily, general substrate transporter (InterPro:IPR016196); BEST Arabidopsis thaliana protein match is: zinc induced facilitator 1 (TAIR:AT5G13740.1); Has 19294 Blast hits to 18859 proteins in 2587 species: Archae - 361; Bacteria - 14367; Metazoa - 620; Fungi - 2172; Plants - 389; Viruses - 0; Other Eukaryotes - 1385 (source: NCBI BLink).

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003076.8 Reference assembly

      Range
      4437804..4441701
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_180705.3 → NP_851036.1  zinc induced facilitator-like 1 [Arabidopsis thaliana]

      See identical proteins and their annotated locations for NP_851036.1

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      C0Z283, Q2V381, Q56WZ9, Q8LC71, Q94BZ1, Q9FKI7
      UniProtKB/TrEMBL
      A0A178UFA6, A0A5S9Y465
      Conserved Domains (1) summary
      cd17330
      Location:41 → 470
      MFS_SLC46_TetA_like; Eukaryotic Solute carrier 46 (SLC46) family, Bacterial Tetracycline resistance proteins, and similar proteins of the Major Facilitator Superfamily of transporters

    2. NM_001343292.1 → NP_001318556.1  zinc induced facilitator-like 1 [Arabidopsis thaliana]

      Status: REVIEWED

      UniProtKB/TrEMBL
      A0A178UCE9

    3. NM_001036800.2 → NP_001031877.1  zinc induced facilitator-like 1 [Arabidopsis thaliana]

      See identical proteins and their annotated locations for NP_001031877.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      A0A178UCE9
      Conserved Domains (2) summary
      cd06174
      Location:38 → 190
      MFS; The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of ...
      pfam07690
      Location:41 → 378
      MFS_1; Major Facilitator Superfamily

    4. NM_121378.5 → NP_568290.3  zinc induced facilitator-like 1 [Arabidopsis thaliana]

      See identical proteins and their annotated locations for NP_568290.3

      Status: REVIEWED

      UniProtKB/TrEMBL
      A0A5S9Y465
      Conserved Domains (2) summary
      cd06174
      Location:1 → 383
      MFS; The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of ...
      pfam07690
      Location:1 → 342
      MFS_1; Major Facilitator Superfamily
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q94BZ1.1

    Gene LinkOut

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