U.S. flag

An official website of the United States government

Format

Send to:

Choose Destination

Links from GEO Profiles

    • Showing Current items.

    NIC3 nicotinamidase 3 [ Arabidopsis thaliana (thale cress) ]

    Gene ID: 832386, updated on 18-Sep-2024

    Summary

    Go to the top of the page Help
    Official Symbol
    NIC3
    Official Full Name
    nicotinamidase 3
    Primary source
    TAIR:AT5G23220
    Locus tag
    AT5G23220
    See related
    Araport:AT5G23220
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Arabidopsis thaliana (ecotype: Columbia)
    Lineage
    Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta; Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis
    Also known as
    MKD15.8; MKD15_8; nicotinamidase 3
    NEW
    Try the new Gene table
    Try the new Transcript table

    Genomic context

    Go to the top of the page Help
    See NIC3 in Genome Data Viewer
    Location:
    chromosome: 5
    Exon count:
    1
    Sequence:
    Chromosome: 5; NC_003076.8 (7819608..7820760, complement)

    Chromosome 5 - NC_003076.8Genomic Context describing neighboring genes Neighboring gene serine carboxypeptidase-like 34 Neighboring gene Defensin-like (DEFL) family protein Neighboring gene ncRNA Neighboring gene DNAJ heat shock N-terminal domain-containing protein Neighboring gene miscRNA Neighboring gene nicotinamidase 2

    Genomic regions, transcripts, and products

    Go to the top of the page Help
    Genomic Sequence:
    NC_003076.8

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

    Go to the top of the pageHelp

    Related articles in PubMed

    1. Overexpression of nicotinamidase 3 (NIC3) gene and the exogenous application of nicotinic acid (NA) enhance drought tolerance and increase biomass in Arabidopsis. Ahmad Z, et al. Plant Mol Biol, 2021 Sep. PMID 34460049
    2. Nicotinamidase activity is important for germination. Hunt L, et al. Plant J, 2007 Aug. PMID 17587307
    3. Evidence for network evolution in an Arabidopsis interactome map. Arabidopsis Interactome Mapping Consortium. Science, 2011 Jul 29. PMID 21798944, Free PMC Article
    4. Sequence and analysis of chromosome 5 of the plant Arabidopsis thaliana. Tabata S, et al. Nature, 2000 Dec 14. PMID 11130714

    GeneRIFs: Gene References Into Functions

    What's a GeneRIF?
    1. Overexpression of nicotinamidase 3 (NIC3) gene and the exogenous application of nicotinic acid (NA) enhance drought tolerance and increase biomass in Arabidopsis.
      Title: Overexpression of nicotinamidase 3 (NIC3) gene and the exogenous application of nicotinic acid (NA) enhance drought tolerance and increase biomass in Arabidopsis.
    2. able to degrade nicotinamide
      Title: Nicotinamidase activity is important for germination.
    Submit: New GeneRIF Correction

    Pathways from PubChem

    Go to the top of the page

    Interactions

    Go to the top of the page Help
    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

    Go to the top of the page Help

    Homology

    NM_122228.3

    Gene Ontology Provided by TAIR

    Function Evidence Code Pubs
    enables nicotinamidase activity IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in response to acid chemical IEP
    Inferred from Expression Pattern
    more info
    		 PubMed 
    Component Evidence Code Pubs
    is_active_in cellular_component ND
    No biological Data available
    more info
    		  

    General protein information

    Go to the top of the page Help
    Preferred Names
    nicotinamidase 3
    NP_197713.1
    • nicotinamidase 3 (NIC3); FUNCTIONS IN: nicotinamidase activity, catalytic activity; INVOLVED IN: metabolic process; EXPRESSED IN: root; CONTAINS InterPro DOMAIN/s: Isochorismatase-like (InterPro:IPR000868); BEST Arabidopsis thaliana protein match is: nicotinamidase 2 (TAIR:AT5G23230.1); Has 1807 Blast hits to 1807 proteins in 277 species: Archae - 0; Bacteria - 0; Metazoa - 736; Fungi - 347; Plants - 385; Viruses - 0; Other Eukaryotes - 339 (source: NCBI BLink).

    NCBI Reference Sequences (RefSeq)

    Go to the top of the page Help

    NEW Try the new Transcript table

    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003076.8 Reference assembly

      Range
      7819608..7820760 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_122228.3 → NP_197713.1  nicotinamidase 3 [Arabidopsis thaliana]

      See identical proteins and their annotated locations for NP_197713.1

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      Q9FMX8
      UniProtKB/TrEMBL
      A0A5S9Y6R4, A0A654G3E0
      Conserved Domains (1) summary
      PLN02621
      Location:1 → 198
      PLN02621; nicotinamidase
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q9FMX8.1

    Gene LinkOut

    The following LinkOut resources are supplied by external providers. These providers are responsible for maintaining the links.

    Molecular Biology Databases
    Research Materials
    Tools