TIFY domain/Divergent CCT motif family protein [Arabidopsis thaliana (thale cress)] - Gene

Summary

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Official Full Name: TIFY domain/Divergent CCT motif family protein
Primary source: TAIR:AT4G14720
Locus tag: AT4G14720
See related: Araport:AT4G14720
Gene type: protein coding
RefSeq status: REVIEWED
Organism: Arabidopsis thaliana (ecotype: Columbia)
Lineage: Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta; Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis
Also known as: DL3400C; FCAALL.297; PEAPOD 2; PPD2; TIFY4B
Summary: PPD2 (and its paralog, PPD1) encode plant-specific putative DNA-binding proteins. Deletion of the PPD locus increases leaf lamina size and results in dome-shaped rather than flat leaves. Siliques are also altered in shape because of extra lamina growth.
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Genomic context

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See in Genome Data Viewer

Location:: chromosome: 4

Exon count:: 9

Sequence:: Chromosome: 4; NC_003075.7 (8431973..8435105, complement)

Chromosome 4 - NC_003075.7 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Go to reference sequence details

Genomic Sequence:: NC_003075.7

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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GeneRIFs: Gene References Into Functions

What's a GeneRIF?

Arabidopsis PEAPODs function with LIKE HETEROCHROMATIN PROTEIN1 to regulate lateral organ growth.
Title: Arabidopsis PEAPODs function with LIKE HETEROCHROMATIN PROTEIN1 to regulate lateral organ growth.
Transcriptional regulator PEAPOD2 (PPD2) and NOVEL INTERACTOR OF JAZ (NINJA) mutants have a similar increase in the expression of CYCLIN D3;2 (CYCD3;2).
Title: Arabidopsis Leaf Flatness Is Regulated by PPD2 and NINJA through Repression of CYCLIN D3 Genes.
SAP controls organ size by targeting PEAROD1 and PEAPOD2 proteins for degradation in Arabidopsis thaliana.
Title: SCF(SAP) controls organ size by targeting PPD proteins for degradation in Arabidopsis thaliana.
Data show that two proteins containing a KIX (kinase-inducible domain interacting) domain, encoded by AT3G24150 and AT4G32295 and named KIX8 and KIX9 are required for transcriptional regulator PEAPOD2 (PPD2) target gene expression.
Title: A Repressor Protein Complex Regulates Leaf Growth in Arabidopsis.
PPD2 interacts with geminivirus TrAP and can form a complex associated with coat protein promoter sequences required for activation but not repression.
Title: The Arabidopsis PEAPOD2 transcription factor interacts with geminivirus AL2 protein and the coat protein promoter.
PPD locus is composed of two homologous genes, PPD1 and PPD2, which encode putative DNA-binding proteins. Overexpression of PPD reduces lamina size by promoting the early arrest of DMC proliferation during leaf and silique development. [PPD2]
Title: PEAPOD regulates lamina size and curvature in Arabidopsis.

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Interactions

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Products	Interactant	Other Gene	Complex	Source	Pubs	Description

General gene information

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NM_001340962.1

Supported by ESTs:

NM_117557.3

Supported by ESTs:

Gene Ontology Provided by TAIR

Function	Evidence Code	Pubs
enables protein binding	IPI Inferred from Physical Interaction more info	PubMed

Process	Evidence Code	Pubs
acts_upstream_of_or_within leaf development	IMP Inferred from Mutant Phenotype more info	PubMed
acts_upstream_of_or_within regulation of leaf morphogenesis	IMP Inferred from Mutant Phenotype more info	PubMed

Component	Evidence Code	Pubs
located_in nucleus	IDA Inferred from Direct Assay more info	PubMed
located_in nucleus	ISM Inferred from Sequence Model more info

General protein information

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Preferred Names: TIFY domain/Divergent CCT motif family protein

NP_193208.2

TIFY domain/Divergent CCT motif family protein; CONTAINS InterPro DOMAIN/s: Tify (InterPro:IPR010399), Acireductone dioxygenase, ARD (InterPro:IPR004313), CCT domain-like (InterPro:IPR018467); BEST Arabidopsis thaliana protein match is: TIFY domain/Divergent CCT motif family protein (TAIR:AT4G14713.1); Has 315 Blast hits to 312 proteins in 29 species: Archae - 0; Bacteria - 0; Metazoa - 0; Fungi - 0; Plants - 313; Viruses - 0; Other Eukaryotes - 2 (source: NCBI BLink).

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

NC_003075.7 Reference assembly

Range

8431973..8435105 complement

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GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

NM_117557.3 → NP_193208.2 TIFY domain/Divergent CCT motif family protein [Arabidopsis thaliana]

See identical proteins and their annotated locations for NP_193208.2

Status: REVIEWED

UniProtKB/Swiss-Prot

O23328, Q8GY55

UniProtKB/TrEMBL

A0A178UTC8, A0A190V505, A0A384LC06, A0A7G2F0B1

Conserved Domains (2) summary

pfam06200
Location:157 → 185

tify; tify domain

pfam09425
Location:233 → 254

CCT_2; Divergent CCT motif
NM_001340962.1 → NP_001329427.1 TIFY domain/Divergent CCT motif family protein [Arabidopsis thaliana]

Status: REVIEWED

UniProtKB/TrEMBL

A0A1P8B7N6, A0A654FP90, A0A7G2F0B1

Conserved Domains (2) summary

pfam06200
Location:157 → 185

tify; tify domain

pfam09425
Location:233 → 254

CCT_2; Divergent CCT motif