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    MDA1 Mitochondrial transcription termination factor family protein [ Arabidopsis thaliana (thale cress) ]

    Gene ID: 827109, updated on 18-Sep-2024

    Summary

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    Official Symbol
    MDA1
    Official Full Name
    Mitochondrial transcription termination factor family protein
    Primary source
    TAIR:AT4G14605
    Locus tag
    AT4G14605
    See related
    Araport:AT4G14605
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Arabidopsis thaliana (ecotype: Columbia)
    Lineage
    Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta; Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis
    Also known as
    MTERF DEFECTIVE IN Arabidopsis1
    Summary
    Encodes a putative mitochondrial transcription termination factor whose mutation results in plants that exhibit altered chloroplast morphology and plant growth, and reduced pigmentation of cotyledons, leaves, stems and sepals.
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    Genomic context

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    See MDA1 in Genome Data Viewer
    Location:
    chromosome: 4
    Exon count:
    5
    Sequence:
    Chromosome: 4; NC_003075.7 (8378428..8380714)

    Chromosome 4 - NC_003075.7Genomic Context describing neighboring genes Neighboring gene embryo defective 2739 Neighboring gene Target SNARE coiled-coil domain protein Neighboring gene miscRNA Neighboring gene sporulation-specific protein

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_003075.7

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. The Arabidopsis mTERF-repeat MDA1 protein plays a dual function in transcription and stabilization of specific chloroplast transcripts within the psbE and ndhH operons. Méteignier LV, et al. New Phytol, 2020 Sep. PMID 32343843, Free PMC Article
    2. Arabidopsis MDA1, a nuclear-encoded protein, functions in chloroplast development and abiotic stress responses. Robles P, et al. PLoS One, 2012. PMID 22905186, Free PMC Article
    3. CrY2H-seq: a massively multiplexed assay for deep-coverage interactome mapping. Wanamaker SA, et al. Nat Methods, 2017 Aug. PMID 28650476, Free PMC Article
    4. Sequence and analysis of chromosome 4 of the plant Arabidopsis thaliana. Mayer K, et al. Nature, 1999 Dec 16. PMID 10617198

    GeneRIFs: Gene References Into Functions

    What's a GeneRIF?
    1. The Arabidopsis mTERF-repeat MDA1 protein plays a dual function in transcription and stabilization of specific chloroplast transcripts within the psbE and ndhH operons.
      Title: The Arabidopsis mTERF-repeat MDA1 protein plays a dual function in transcription and stabilization of specific chloroplast transcripts within the psbE and ndhH operons.
    Submit: New GeneRIF Correction

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Homology

    NM_001340949.1
    NM_117541.9

    Gene Ontology Provided by TAIR

    Function Evidence Code Pubs
    enables molecular_function ND
    No biological Data available
    more info
    		  
    Process Evidence Code Pubs
    acts_upstream_of_or_within chloroplast organization IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    acts_upstream_of_or_within response to abscisic acid IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    acts_upstream_of_or_within response to osmotic stress IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    acts_upstream_of_or_within response to salt stress IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in mitochondrion ISM
    Inferred from Sequence Model
    more info
    		  

    General protein information

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    Preferred Names
    Mitochondrial transcription termination factor family protein
    NP_567435.4
    • Mitochondrial transcription termination factor family protein; CONTAINS InterPro DOMAIN/s: Mitochodrial transcription termination factor-related (InterPro:IPR003690); BEST Arabidopsis thaliana protein match is: Mitochondrial transcription termination factor family protein (TAIR:AT2G21710.1); Has 1482 Blast hits to 884 proteins in 83 species: Archae - 0; Bacteria - 0; Metazoa - 114; Fungi - 0; Plants - 1279; Viruses - 0; Other Eukaryotes - 89 (source: NCBI BLink).

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003075.7 Reference assembly

      Range
      8378428..8380714
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_117541.9 → NP_567435.4  Mitochondrial transcription termination factor family protein [Arabidopsis thaliana]

      See identical proteins and their annotated locations for NP_567435.4

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      F4JVI3
      UniProtKB/TrEMBL
      A0A178V738, A0A5S9XSM7
      Conserved Domains (1) summary
      cl19765
      Location:211 → 468
      mTERF

    2. NM_001340949.1 → NP_001327961.1  Mitochondrial transcription termination factor family protein [Arabidopsis thaliana]

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      F4JVI3
      UniProtKB/TrEMBL
      A0A178V738, A0A5S9XSM7
      Conserved Domains (1) summary
      cl19765
      Location:211 → 468
      mTERF
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    F4JVI3.1

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