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    Gal3st4 galactose-3-O-sulfotransferase 4 [ Mus musculus (house mouse) ]

    Gene ID: 330217, updated on 9-Dec-2024

    Summary

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    Official Symbol
    Gal3st4provided by MGI
    Official Full Name
    galactose-3-O-sulfotransferase 4provided by MGI
    Primary source
    MGI:MGI:1916254
    See related
    Ensembl:ENSMUSG00000075593 AllianceGenome:MGI:1916254
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Mus musculus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
    Also known as
    1500031A01Rik
    Summary
    Predicted to enable galactose 3-O-sulfotransferase activity. Predicted to act upstream of or within glycoprotein biosynthetic process. Predicted to be located in membrane. Orthologous to human GAL3ST4 (galactose-3-O-sulfotransferase 4). [provided by Alliance of Genome Resources, Dec 2024]
    Expression
    Biased expression in genital fat pad adult (RPKM 9.2), CNS E11.5 (RPKM 1.4) and 14 other tissues See more
    Orthologs
    human all
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    Genomic context

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    See Gal3st4 in Genome Data Viewer
    Location:
    5 G2; 5 77.0 cM
    Exon count:
    6
    Annotation release Status Assembly Chr Location
    RS_2024_02 current GRCm39 (GCF_000001635.27) 5 NC_000071.7 (138263180..138271261, complement)
    108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 5 NC_000071.6 (138264918..138273057, complement)

    Chromosome 5 - NC_000071.7Genomic Context describing neighboring genes Neighboring gene STARR-positive B cell enhancer ABC_E532 Neighboring gene RIKEN cDNA 6330418K02 gene Neighboring gene late endosomal/lysosomal adaptor, MAPK and MTOR activator 4 Neighboring gene STARR-positive B cell enhancer ABC_E4800 Neighboring gene trafficking protein particle complex 14 Neighboring gene STARR-positive B cell enhancer ABC_E3630 Neighboring gene STAG3 cohesin complex component Neighboring gene glypican 2 cerebroglycan Neighboring gene poliovirus receptor related immunoglobulin domain containing Neighboring gene poliovirus receptor related immunoglobulin domain containing, pseudogene

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Expression

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    • Project title: Mouse ENCODE transcriptome data
    • Description: RNA profiling data sets generated by the Mouse ENCODE project.
    • BioProject: PRJNA66167
    • Publication: PMID 25409824
    • Analysis date: n/a

    Bibliography

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    Related articles in PubMed

    1. Gpr126/Adgrg6 deletion in cartilage models idiopathic scoliosis and pectus excavatum in mice. Karner CM, et al. Hum Mol Genet, 2015 Aug 1. PMID 25954032, Free PMC Article
    2. A conditional knockout resource for the genome-wide study of mouse gene function. Skarnes WC, et al. Nature, 2011 Jun 15. PMID 21677750, Free PMC Article
    3. Normalization and subtraction: two approaches to facilitate gene discovery. Bonaldo MF, et al. Genome Res, 1996 Sep. PMID 8889548
    4. A high-resolution anatomical atlas of the transcriptome in the mouse embryo. Diez-Roux G, et al. PLoS Biol, 2011 Jan 18. PMID 21267068, Free PMC Article
    5. Antisense transcription in the mammalian transcriptome. Katayama S, et al. Science, 2005 Sep 2. PMID 16141073

    See all (12) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Pathways from PubChem

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    General gene information

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    Homology

    Gene Ontology Provided by MGI

    Function Evidence Code Pubs
    enables galactose 3-O-sulfotransferase activity IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    enables galactose 3-O-sulfotransferase activity ISO
    Inferred from Sequence Orthology
    more info
    		  
    Process Evidence Code Pubs
    acts_upstream_of_or_within glycoprotein biosynthetic process ISO
    Inferred from Sequence Orthology
    more info
    		  
    Component Evidence Code Pubs
    located_in membrane ISO
    Inferred from Sequence Orthology
    more info
    		  

    General protein information

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    Preferred Names
    galactose-3-O-sulfotransferase 4

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001347507.1 → NP_001334436.1  galactose-3-O-sulfotransferase 4 isoform 2

      Status: VALIDATED

      Source sequence(s)
      AC159257
      Consensus CDS
      CCDS84982.1
      UniProtKB/TrEMBL
      E9Q7N6, Q3UTX9
      Related
      ENSMUSP00000125084.2, ENSMUST00000161647.8

    2. NM_001361283.1 → NP_001348212.1  galactose-3-O-sulfotransferase 4 isoform 1

      Status: VALIDATED

      Source sequence(s)
      AK138993, AK162468, BY282992, BY619135, CX243736
      Consensus CDS
      CCDS19798.1
      UniProtKB/TrEMBL
      Q3UTX9, Q3V1B8
      Related
      ENSMUSP00000124841.2, ENSMUST00000161279.8
      Conserved Domains (1) summary
      cl22970
      Location:1 → 463
      Sulfotransfer_2; Sulfotransferase family

    RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCm39 C57BL/6J

    Genomic

    1. NC_000071.7 Reference GRCm39 C57BL/6J

      Range
      138263180..138271261 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_006504583.5 → XP_006504646.1  galactose-3-O-sulfotransferase 4 isoform X3

      UniProtKB/TrEMBL
      Q3TRU1
      Conserved Domains (1) summary
      cl22970
      Location:1 → 316
      Sulfotransfer_2; Sulfotransferase family

    2. XM_017320935.3 → XP_017176424.1  galactose-3-O-sulfotransferase 4 isoform X1

      UniProtKB/TrEMBL
      Q3UTX9, Q3V1B8
      Conserved Domains (1) summary
      cl22970
      Location:1 → 463
      Sulfotransfer_2; Sulfotransferase family

    3. XM_036165230.1 → XP_036021123.1  galactose-3-O-sulfotransferase 4 isoform X2

      UniProtKB/TrEMBL
      Q3UTX9
      Conserved Domains (1) summary
      cl22970
      Location:4 → 454
      Sulfotransfer_2; Sulfotransferase family

    4. XM_036165229.1 → XP_036021122.1  galactose-3-O-sulfotransferase 4 isoform X1

      UniProtKB/TrEMBL
      Q3UTX9, Q3V1B8
      Related
      ENSMUSP00000098099.2, ENSMUST00000100530.8
      Conserved Domains (1) summary
      cl22970
      Location:1 → 463
      Sulfotransfer_2; Sulfotransferase family

    5. XM_006504582.4 → XP_006504645.1  galactose-3-O-sulfotransferase 4 isoform X2

      UniProtKB/TrEMBL
      Q3UTX9
      Conserved Domains (1) summary
      cl22970
      Location:4 → 454
      Sulfotransfer_2; Sulfotransferase family

    6. XM_006504579.5 → XP_006504642.1  galactose-3-O-sulfotransferase 4 isoform X1

      See identical proteins and their annotated locations for XP_006504642.1

      UniProtKB/TrEMBL
      Q3UTX9, Q3V1B8
      Conserved Domains (1) summary
      cl22970
      Location:1 → 463
      Sulfotransfer_2; Sulfotransferase family

    Suppressed Reference Sequence(s)

    The following Reference Sequences have been suppressed. Explain

    1. NM_001033416.2: Suppressed sequence

      Description
      NM_001033416.2: This RefSeq has been removed because currently there is insufficient support for the transcript.
    Nucleotide Protein Strain
    Heading Accession and Version

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