U.S. flag

An official website of the United States government

Format

Send to:

Choose Destination

Links from GEO Profiles

    • Showing Current items.

    CDPF1 cysteine rich DPF motif domain containing 1 [ Homo sapiens (human) ]

    Gene ID: 150383, updated on 10-Dec-2024

    Summary

    Go to the top of the page Help
    Official Symbol
    CDPF1provided by HGNC
    Official Full Name
    cysteine rich DPF motif domain containing 1provided by HGNC
    Primary source
    HGNC:HGNC:33710
    See related
    Ensembl:ENSG00000205643 AllianceGenome:HGNC:33710
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Homo sapiens
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
    Also known as
    CDKN1A; C22orf40
    Expression
    Ubiquitous expression in ovary (RPKM 2.6), spleen (RPKM 2.6) and 25 other tissues See more
    Orthologs
    mouse all
    NEW
    Try the new Gene table
    Try the new Transcript table

    Genomic context

    Go to the top of the page Help
    See CDPF1 in Genome Data Viewer
    Location:
    22q13.31
    Exon count:
    5
    Annotation release Status Assembly Chr Location
    RS_2024_08 current GRCh38.p14 (GCF_000001405.40) 22 NC_000022.11 (46244013..46250293, complement)
    RS_2024_08 current T2T-CHM13v2.0 (GCF_009914755.1) 22 NC_060946.1 (46728714..46734994, complement)
    RS_2024_09 previous assembly GRCh37.p13 (GCF_000001405.25) 22 NC_000022.10 (46639910..46646190, complement)

    Chromosome 22 - NC_000022.11Genomic Context describing neighboring genes Neighboring gene uncharacterized LOC124905137 Neighboring gene uncharacterized LOC124905138 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr22:46533901-46534402 Neighboring gene ATAC-STARR-seq lymphoblastoid silent region 13903 Neighboring gene ATAC-STARR-seq lymphoblastoid silent region 13904 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 19232 Neighboring gene uncharacterized LOC105373074 Neighboring gene peroxisome proliferator activated receptor alpha Neighboring gene H3K4me1 hESC enhancer GRCh37_chr22:46591783-46592283 Neighboring gene NANOG-H3K27ac-H3K4me1 hESC enhancer GRCh37_chr22:46596710-46597314 Neighboring gene NANOG-H3K27ac-H3K4me1 hESC enhancer GRCh37_chr22:46597315-46597919 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr22:46610267-46610768 Neighboring gene ATAC-STARR-seq lymphoblastoid silent region 13905 Neighboring gene H3K27ac-H3K4me1 hESC enhancer GRCh37_chr22:46645973-46646480 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 19233 Neighboring gene ATAC-STARR-seq lymphoblastoid silent region 13907 Neighboring gene ATAC-STARR-seq lymphoblastoid silent region 13908 Neighboring gene polycystin family receptor for egg jelly Neighboring gene tetratricopeptide repeat domain 38

    Genomic regions, transcripts, and products

    Go to the top of the page Help

    Go to nucleotide: Graphics FASTA GenBank

    Expression

    Go to the top of the page Help
    • Project title: Tissue-specific circular RNA induction during human fetal development
    • Description: 35 human fetal samples from 6 tissues (3 - 7 replicates per tissue) collected between 10 and 20 weeks gestational time were sequenced using Illumina TruSeq Stranded Total RNA
    • BioProject: PRJNA270632
    • Publication: PMID 26076956
    • Analysis date: Mon Apr 2 22:54:59 2018

    Bibliography

    Go to the top of the pageHelp

    Related articles in PubMed

    1. A genome annotation-driven approach to cloning the human ORFeome. Collins JE, et al. Genome Biol, 2004. PMID 15461802, Free PMC Article
    2. Assessment of community efforts to advance network-based prediction of protein-protein interactions. Wang XW, et al. Nat Commun, 2023 Mar 22. PMID 36949045, Free PMC Article
    3. Systematic protein-protein interaction mapping for clinically relevant human GPCRs. Sokolina K, et al. Mol Syst Biol, 2017 Mar 15. PMID 28298427, Free PMC Article
    4. A dual-activity topoisomerase complex regulates mRNA translation and turnover. Su S, et al. Nucleic Acids Res, 2022 Jul 8. PMID 35748872, Free PMC Article
    5. Interactions of pathological hallmark proteins: tubulin polymerization promoting protein/p25, beta-amyloid, and alpha-synuclein. Oláh J, et al. J Biol Chem, 2011 Sep 30. PMID 21832049, Free PMC Article

    See all (10) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Phenotypes

    Go to the top of the page Help

    Find tests for this gene in the NIH Genetic Testing Registry (GTR)

    Review eQTL and phenotype association data in this region using PheGenI

    Variation

    Go to the top of the page Help

    See variants in ClinVar

    See studies and variants in dbVar

    See Variation Viewer (GRCh37.p13)

    See Variation Viewer (GRCh38)

    Interactions

    Go to the top of the page Help
    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

    Go to the top of the page Help

    Markers

    Homology

    Gene Ontology Provided by GOA

    Function Evidence Code Pubs
    enables protein binding IPI
    Inferred from Physical Interaction
    more info
    		 PubMed 

    General protein information

    Go to the top of the page Help
    Preferred Names
    cysteine-rich DPF motif domain-containing protein 1
    Names
    UPF0595 protein C22orf40

    NCBI Reference Sequences (RefSeq)

    Go to the top of the page Help

    NEW Try the new Transcript table

    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_207327.5 → NP_997210.3  cysteine-rich DPF motif domain-containing protein 1

      See identical proteins and their annotated locations for NP_997210.3

      Status: VALIDATED

      Source sequence(s)
      AW085176, BC067871
      Consensus CDS
      CCDS33670.1
      UniProtKB/Swiss-Prot
      A6NCA1, A9IU12, A9IU16, Q3ZCR8, Q6NVV7
      UniProtKB/TrEMBL
      F6RAJ7
      Related
      ENSP00000325301.3, ENST00000314567.8
      Conserved Domains (1) summary
      pfam10170
      Location:13 → 106
      C6_DPF; Cysteine-rich domain

    RefSeqs of Annotated Genomes: GCF_000001405.40-RS_2024_08

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCh38.p14 Primary Assembly

    Genomic

    1. NC_000022.11 Reference GRCh38.p14 Primary Assembly

      Range
      46244013..46250293 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_011529960.3 → XP_011528262.1  cysteine-rich DPF motif domain-containing protein 1 isoform X1

      See identical proteins and their annotated locations for XP_011528262.1

      Conserved Domains (1) summary
      pfam10170
      Location:13 → 75
      C6_DPF; Cysteine-rich domain

    2. XM_011529965.3 → XP_011528267.1  cysteine-rich DPF motif domain-containing protein 1 isoform X2

      See identical proteins and their annotated locations for XP_011528267.1

      UniProtKB/Swiss-Prot
      A6NCA1, A9IU12, A9IU16, Q3ZCR8, Q6NVV7
      UniProtKB/TrEMBL
      F6RAJ7
      Conserved Domains (1) summary
      pfam10170
      Location:13 → 106
      C6_DPF; Cysteine-rich domain

    3. XM_047441165.1 → XP_047297121.1  cysteine-rich DPF motif domain-containing protein 1 isoform X3

      UniProtKB/TrEMBL
      F6UL18
      Related
      ENSP00000385460.1, ENST00000404744.1

    Alternate T2T-CHM13v2.0

    Genomic

    1. NC_060946.1 Alternate T2T-CHM13v2.0

      Range
      46728714..46734994 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_054325185.1 → XP_054181160.1  cysteine-rich DPF motif domain-containing protein 1 isoform X1

    2. XM_054325186.1 → XP_054181161.1  cysteine-rich DPF motif domain-containing protein 1 isoform X2

      UniProtKB/TrEMBL
      F6RAJ7

    3. XM_054325187.1 → XP_054181162.1  cysteine-rich DPF motif domain-containing protein 1 isoform X3

    Suppressed Reference Sequence(s)

    The following Reference Sequences have been suppressed. Explain

    1. NM_001008917.1: Suppressed sequence

      Description
      NM_001008917.1: This RefSeq was permanently suppressed because it is a nonsense-mediated mRNA decay (NMD) candidate.
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q6NVV7.1 GenPept UniProtKB/Swiss-Prot:Q6NVV7

    Gene LinkOut

    The following LinkOut resources are supplied by external providers. These providers are responsible for maintaining the links.

    Chemical Information
    Molecular Biology Databases
    Research Materials
    Tools