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These reference sequences exist independently of genome builds. Explain
These reference sequences are curated independently of the genome
annotation cycle, so their versions may not match the RefSeq versions in the current
genome build. Identify version mismatches by comparing the version of the RefSeq in
this section to the one reported in Genomic regions,
transcripts, and products above.
mRNA and Protein(s)
-
NM_001242837.2 → NP_001229766.1 AP-2 complex subunit alpha-2 isoform 1
See identical proteins and their annotated locations for NP_001229766.1
Status: REVIEWED
- Description
- Transcript Variant: This variant (1) represents the longest transcript and encodes the longer isoform (1).
- Source sequence(s)
-
AK223558, AP006477, BU735076, DB461570
- Consensus CDS
-
CCDS73234.1
- UniProtKB/TrEMBL
-
B7Z5S9
- Related
- ENSP00000327694.5, ENST00000332231.9
- Conserved Domains (5) summary
-
- smart00809
Location:718 → 821
- Alpha_adaptinC2; Adaptin C-terminal domain
- pfam01602
Location:29 → 591
- Adaptin_N; Adaptin N terminal region
- pfam02296
Location:827 → 935
- Alpha_adaptin_C; Alpha adaptin AP2, C-terminal domain
- pfam12717
Location:163 → 235
- Cnd1; non-SMC mitotic condensation complex subunit 1
- sd00044
Location:332 → 355
- HEAT; HEAT repeat [structural motif]
-
NM_012305.4 → NP_036437.1 AP-2 complex subunit alpha-2 isoform 2
See identical proteins and their annotated locations for NP_036437.1
Status: REVIEWED
- Description
- Transcript Variant: This variant (2) uses an alternate in-frame splice site in the central coding region, compared to variant 1, resulting in an isoform (2) that is 1 aa shorter than isoform 1.
- Source sequence(s)
-
AP006477, BC006155, BU735076, DB461570
- Consensus CDS
-
CCDS44512.1
- UniProtKB/Swiss-Prot
- O75403, O94973, Q53ET1, Q96SI8
- UniProtKB/TrEMBL
-
B7Z5S9
- Related
- ENSP00000413234.3, ENST00000448903.7
- Conserved Domains (5) summary
-
- smart00809
Location:717 → 820
- Alpha_adaptinC2; Adaptin C-terminal domain
- pfam01602
Location:29 → 590
- Adaptin_N; Adaptin N terminal region
- pfam02296
Location:826 → 934
- Alpha_adaptin_C; Alpha adaptin AP2, C-terminal domain
- pfam12717
Location:163 → 235
- Cnd1; non-SMC mitotic condensation complex subunit 1
- sd00044
Location:331 → 354
- HEAT; HEAT repeat [structural motif]
RNA
-
NR_144509.2 RNA Sequence
Status: REVIEWED
- Description
- Transcript Variant: This variant (3) uses an alternate splice junction and lacks an alternate exon compared to variant 1. This variant is represented as non-coding because the use of the 5'-most expected translational start codon renders the transcript a candidate for nonsense-mediated mRNA decay (NMD).
- Source sequence(s)
-
AP006477, AP006623
- Related
-
ENST00000687890.1
-
NR_144510.2 RNA Sequence
Status: REVIEWED
- Description
- Transcript Variant: This variant (4) lacks an alternate exon compared to variant 1. This variant is represented as non-coding because the use of the 5'-most expected translational start codon renders the transcript a candidate for nonsense-mediated mRNA decay (NMD).
- Source sequence(s)
-
AP006477, AP006623
The following sections contain reference sequences that belong to a
specific genome build. Explain
This section includes genomic Reference
Sequences (RefSeqs) from all assemblies on which this gene is annotated, such as
RefSeqs for chromosomes and scaffolds (contigs) from both reference and alternate
assemblies. Model RNAs and proteins are also reported here.
Reference GRCh38.p14 Primary Assembly
Genomic
-
NC_000011.10 Reference GRCh38.p14 Primary Assembly
- Range
-
925870..1012240
- Download
- GenBank, FASTA, Sequence Viewer (Graphics)
mRNA and Protein(s)
-
XM_047426480.1 → XP_047282436.1 AP-2 complex subunit alpha-2 isoform X1
- UniProtKB/TrEMBL
-
A0A0G2JS82
-
XM_047426479.1 → XP_047282435.1 AP-2 complex subunit alpha-2 isoform X1
- UniProtKB/TrEMBL
-
A0A0G2JS82
-
XM_011519930.4 → XP_011518232.1 AP-2 complex subunit alpha-2 isoform X3
- UniProtKB/TrEMBL
-
A0A8I5KPP9
- Related
- ENSP00000431630.1, ENST00000528815.5
- Conserved Domains (3) summary
-
- pfam01602
Location:29 → 591
- Adaptin_N; Adaptin N terminal region
- pfam12717
Location:163 → 235
- Cnd1; non-SMC mitotic condensation complex subunit 1
- sd00044
Location:369 → 398
- HEAT; HEAT repeat [structural motif]
-
XM_011519929.2 → XP_011518231.1 AP-2 complex subunit alpha-2 isoform X1
See identical proteins and their annotated locations for XP_011518231.1
- UniProtKB/TrEMBL
-
A0A0G2JS82
- Conserved Domains (3) summary
-
- smart00809
Location:642 → 745
- Alpha_adaptinC2; Adaptin C-terminal domain
- COG5096
Location:1 → 525
- COG5096; Vesicle coat complex, various subunits [Intracellular trafficking, secretion, and vesicular transport]
- pfam02296
Location:751 → 859
- Alpha_adaptin_C; Alpha adaptin AP2, C-terminal domain
-
XM_047426482.1 → XP_047282438.1 AP-2 complex subunit alpha-2 isoform X1
- UniProtKB/TrEMBL
-
A0A0G2JS82
-
XM_047426485.1 → XP_047282441.1 AP-2 complex subunit alpha-2 isoform X1
- UniProtKB/TrEMBL
-
A0A0G2JS82
-
XM_047426484.1 → XP_047282440.1 AP-2 complex subunit alpha-2 isoform X2
- UniProtKB/TrEMBL
-
A0A0G2JS82
-
XM_047426481.1 → XP_047282437.1 AP-2 complex subunit alpha-2 isoform X1
- UniProtKB/TrEMBL
-
A0A0G2JS82
Reference GRCh38.p14 ALT_REF_LOCI_2
Genomic
-
NT_187656.1 Reference GRCh38.p14 ALT_REF_LOCI_2
- Range
-
14000..74983
- Download
- GenBank, FASTA, Sequence Viewer (Graphics)
Reference GRCh38.p14 ALT_REF_LOCI_3
Genomic
-
NT_187681.1 Reference GRCh38.p14 ALT_REF_LOCI_3
- Range
-
14000..81831
- Download
- GenBank, FASTA, Sequence Viewer (Graphics)
Alternate T2T-CHM13v2.0
Genomic
-
NC_060935.1 Alternate T2T-CHM13v2.0
- Range
-
977298..1071157
- Download
- GenBank, FASTA, Sequence Viewer (Graphics)
mRNA and Protein(s)
-
XM_054367870.1 → XP_054223845.1 AP-2 complex subunit alpha-2 isoform X1
- UniProtKB/TrEMBL
-
A0A0G2JS82
-
XM_054367869.1 → XP_054223844.1 AP-2 complex subunit alpha-2 isoform X1
- UniProtKB/TrEMBL
-
A0A0G2JS82
-
XM_054367875.1 → XP_054223850.1 AP-2 complex subunit alpha-2 isoform X3
- UniProtKB/TrEMBL
-
A0A8I5KPP9
-
XM_054367868.1 → XP_054223843.1 AP-2 complex subunit alpha-2 isoform X1
- UniProtKB/TrEMBL
-
A0A0G2JS82
-
XM_054367872.1 → XP_054223847.1 AP-2 complex subunit alpha-2 isoform X1
- UniProtKB/TrEMBL
-
A0A0G2JS82
-
XM_054367874.1 → XP_054223849.1 AP-2 complex subunit alpha-2 isoform X1
- UniProtKB/TrEMBL
-
A0A0G2JS82
-
XM_054367873.1 → XP_054223848.1 AP-2 complex subunit alpha-2 isoform X2
- UniProtKB/TrEMBL
-
A0A0G2JS82
-
XM_054367871.1 → XP_054223846.1 AP-2 complex subunit alpha-2 isoform X1
- UniProtKB/TrEMBL
-
A0A0G2JS82