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    CFAP107 cilia and flagella associated protein 107 [ Homo sapiens (human) ]

    Gene ID: 93190, updated on 27-Nov-2024

    Summary

    Official Symbol
    CFAP107provided by HGNC
    Official Full Name
    cilia and flagella associated protein 107provided by HGNC
    Primary source
    HGNC:HGNC:28567
    See related
    Ensembl:ENSG00000157330 AllianceGenome:HGNC:28567
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Homo sapiens
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
    Also known as
    C1orf158
    Summary
    Predicted to be involved in flagellated sperm motility. Located in axonemal microtubule. [provided by Alliance of Genome Resources, Nov 2024]
    Expression
    Restricted expression toward testis (RPKM 23.3) See more
    Orthologs
    NEW
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    Try the new Transcript table

    Genomic context

    See CFAP107 in Genome Data Viewer
    Location:
    1p36.21
    Exon count:
    4
    Annotation release Status Assembly Chr Location
    RS_2024_08 current GRCh38.p14 (GCF_000001405.40) 1 NC_000001.11 (12746200..12763699)
    RS_2024_08 current T2T-CHM13v2.0 (GCF_009914755.1) 1 NC_060925.1 (12290298..12307996)
    RS_2024_09 previous assembly GRCh37.p13 (GCF_000001405.25) 1 NC_000001.10 (12806148..12823847)

    Chromosome 1 - NC_000001.11Genomic Context describing neighboring genes Neighboring gene P300/CBP strongly-dependent group 1 enhancer GRCh37_chr1:12775588-12776787 Neighboring gene arylacetamide deacetylase like 3 Neighboring gene small nucleolar RNA U13 Neighboring gene PRAME family member 12 Neighboring gene PRAME family member 1

    Genomic regions, transcripts, and products

    Expression

    • Project title: HPA RNA-seq normal tissues
    • Description: RNA-seq was performed of tissue samples from 95 human individuals representing 27 different tissues in order to determine tissue-specificity of all protein-coding genes
    • BioProject: PRJEB4337
    • Publication: PMID 24309898
    • Analysis date: Wed Apr 4 07:08:55 2018

    Interactions

    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

    Markers

    Clone Names

    • MGC35194, DKFZp686C0236

    Gene Ontology Provided by GOA

    Process Evidence Code Pubs
    involved_in flagellated sperm motility ISS
    Inferred from Sequence or Structural Similarity
    more info
     
    Component Evidence Code Pubs
    is_active_in axonemal A tubule inner sheath ISS
    Inferred from Sequence or Structural Similarity
    more info
     
    is_active_in axonemal microtubule IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    located_in axonemal microtubule IDA
    Inferred from Direct Assay
    more info
    PubMed 
    located_in axonemal microtubule ISS
    Inferred from Sequence or Structural Similarity
    more info
     
    is_active_in sperm flagellum ISS
    Inferred from Sequence or Structural Similarity
    more info
     

    General protein information

    Preferred Names
    cilia- and flagella-associated protein 107
    Names
    protein CFAP107
    uncharacterized protein C1orf158

    NCBI Reference Sequences (RefSeq)

    NEW Try the new Transcript table

    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001330361.2NP_001317290.1  cilia- and flagella-associated protein 107 isoform 2

      Status: VALIDATED

      Description
      Transcript Variant: This variant (2) lacks an alternate in-frame exon compared to variant 1. The resulting isoform (2) has the same N- and C-termini but is shorter compared to isoform 1.
      Source sequence(s)
      AC244670
      Consensus CDS
      CCDS81264.1
      UniProtKB/TrEMBL
      Q5VUY5
      Related
      ENSP00000365383.3, ENST00000376210.3
    2. NM_152290.4NP_689503.3  cilia- and flagella-associated protein 107 isoform 1

      See identical proteins and their annotated locations for NP_689503.3

      Status: VALIDATED

      Description
      Transcript Variant: This variant (1) represents the longer transcript and encodes the longer isoform (1).
      Source sequence(s)
      AC244670, BC029894, HY002971
      Consensus CDS
      CCDS147.1
      UniProtKB/Swiss-Prot
      Q5VUY4, Q8N1D5
      Related
      ENSP00000477802.1, ENST00000614859.5

    RefSeqs of Annotated Genomes: GCF_000001405.40-RS_2024_08

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCh38.p14 Primary Assembly

    Genomic

    1. NC_000001.11 Reference GRCh38.p14 Primary Assembly

      Range
      12746200..12763699
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    Alternate T2T-CHM13v2.0

    Genomic

    1. NC_060925.1 Alternate T2T-CHM13v2.0

      Range
      12290298..12307996
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)