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These reference sequences exist independently of genome builds. Explain
These reference sequences are curated independently of the genome
annotation cycle, so their versions may not match the RefSeq versions in the current
genome build. Identify version mismatches by comparing the version of the RefSeq in
this section to the one reported in Genomic regions,
transcripts, and products above.
mRNA and Protein(s)
-
NM_001306050.2 → NP_001292979.1 SPRY domain-containing SOCS box protein 2 isoform 1
See identical proteins and their annotated locations for NP_001292979.1
Status: VALIDATED
- Description
- Transcript Variant: This variant (2) differs in the 5' UTR compared to variant 1. Variants 1-4 and 6-7 all encode the same isoform (1).
- Source sequence(s)
-
AC142254
- Consensus CDS
-
CCDS20529.1
- UniProtKB/Swiss-Prot
- O88838, Q8CBA5, Q91Z15
- UniProtKB/TrEMBL
-
D3YX10
- Conserved Domains (2) summary
-
- cd03719
Location:223 → 264
- SOCS_SSB2; SOCS (suppressors of cytokine signaling) box of SSB2 (SPRY domain-containing SOCS box proteins)-like proteins. SSB proteins contain a central SPRY domain and a C-terminal SOCS. SSB2 has been shown to bind to MET, the receptor protein-tyrosine kinase for ...
- cd12906
Location:46 → 217
- SPRY_SOCS1-2-4; SPRY domain in the suppressor of cytokine signaling 1, 2, 4 families (SOCS1, SOCS2, SOCS4)
-
NM_001306051.2 → NP_001292980.1 SPRY domain-containing SOCS box protein 2 isoform 1
See identical proteins and their annotated locations for NP_001292980.1
Status: VALIDATED
- Description
- Transcript Variant: This variant (3) differs in the 5' UTR compared to variant 1. Variants 1-4 and 6-7 all encode the same isoform (1).
- Source sequence(s)
-
AC142254
- Consensus CDS
-
CCDS20529.1
- UniProtKB/Swiss-Prot
- O88838, Q8CBA5, Q91Z15
- UniProtKB/TrEMBL
-
D3YX10
- Related
- ENSMUSP00000041585.4, ENSMUST00000047760.10
- Conserved Domains (2) summary
-
- cd03719
Location:223 → 264
- SOCS_SSB2; SOCS (suppressors of cytokine signaling) box of SSB2 (SPRY domain-containing SOCS box proteins)-like proteins. SSB proteins contain a central SPRY domain and a C-terminal SOCS. SSB2 has been shown to bind to MET, the receptor protein-tyrosine kinase for ...
- cd12906
Location:46 → 217
- SPRY_SOCS1-2-4; SPRY domain in the suppressor of cytokine signaling 1, 2, 4 families (SOCS1, SOCS2, SOCS4)
-
NM_001306052.2 → NP_001292981.1 SPRY domain-containing SOCS box protein 2 isoform 1
See identical proteins and their annotated locations for NP_001292981.1
Status: VALIDATED
- Description
- Transcript Variant: This variant (4) differs in the 5' UTR compared to variant 1. Variants 1-4 and 6-7 all encode the same isoform (1).
- Source sequence(s)
-
AC142254
- Consensus CDS
-
CCDS20529.1
- UniProtKB/Swiss-Prot
- O88838, Q8CBA5, Q91Z15
- UniProtKB/TrEMBL
-
D3YX10
- Related
- ENSMUSP00000118347.2, ENSMUST00000143040.8
- Conserved Domains (2) summary
-
- cd03719
Location:223 → 264
- SOCS_SSB2; SOCS (suppressors of cytokine signaling) box of SSB2 (SPRY domain-containing SOCS box proteins)-like proteins. SSB proteins contain a central SPRY domain and a C-terminal SOCS. SSB2 has been shown to bind to MET, the receptor protein-tyrosine kinase for ...
- cd12906
Location:46 → 217
- SPRY_SOCS1-2-4; SPRY domain in the suppressor of cytokine signaling 1, 2, 4 families (SOCS1, SOCS2, SOCS4)
-
NM_001306053.2 → NP_001292982.1 SPRY domain-containing SOCS box protein 2 isoform 2
Status: VALIDATED
- Description
- Transcript Variant: This variant (5) uses an alternate splice site in the coding region, which results in a frameshift and an early stop codon, compared to variant 1. It encodes isoform 2, which has a shorter and distinct C-terminus, compared to isoform 1. Variants 5 and 8-10 all encode the same isoform (2).
- Source sequence(s)
-
AC142254
- UniProtKB/TrEMBL
-
D3Z7N7
- Conserved Domains (1) summary
-
- cd12906
Location:46 → 201
- SPRY_SOCS1-2-4; SPRY domain in the suppressor of cytokine signaling 1, 2, 4 families (SOCS1, SOCS2, SOCS4)
-
NM_001409886.1 → NP_001396815.1 SPRY domain-containing SOCS box protein 2 isoform 1
Status: VALIDATED
- Source sequence(s)
-
AC142254
- UniProtKB/Swiss-Prot
- O88838, Q8CBA5, Q91Z15
- UniProtKB/TrEMBL
-
D3YX10
-
NM_001409887.1 → NP_001396816.1 SPRY domain-containing SOCS box protein 2 isoform 1
Status: VALIDATED
- Source sequence(s)
-
AC142254
- UniProtKB/Swiss-Prot
- O88838, Q8CBA5, Q91Z15
- UniProtKB/TrEMBL
-
D3YX10
-
NM_001409888.1 → NP_001396817.1 SPRY domain-containing SOCS box protein 2 isoform 2
Status: VALIDATED
- Source sequence(s)
-
AC142254
- UniProtKB/TrEMBL
-
D3Z7N7
-
NM_001409889.1 → NP_001396818.1 SPRY domain-containing SOCS box protein 2 isoform 2
Status: VALIDATED
- Source sequence(s)
-
AC142254
- UniProtKB/TrEMBL
-
D3Z7N7
-
NM_001409890.1 → NP_001396819.1 SPRY domain-containing SOCS box protein 2 isoform 2
Status: VALIDATED
- Source sequence(s)
-
AC142254
- UniProtKB/TrEMBL
-
D3Z7N7
-
NM_013539.3 → NP_038567.1 SPRY domain-containing SOCS box protein 2 isoform 1
See identical proteins and their annotated locations for NP_038567.1
Status: VALIDATED
- Description
- Transcript Variant: This variant (1) encodes the longer isoform (1). Variants 1-4 and 6-7 all encode the same isoform (1).
- Source sequence(s)
-
AC142254
- Consensus CDS
-
CCDS20529.1
- UniProtKB/Swiss-Prot
- O88838, Q8CBA5, Q91Z15
- UniProtKB/TrEMBL
-
D3YX10
- Related
- ENSMUSP00000060124.5, ENSMUST00000052727.5
- Conserved Domains (2) summary
-
- cd03719
Location:223 → 264
- SOCS_SSB2; SOCS (suppressors of cytokine signaling) box of SSB2 (SPRY domain-containing SOCS box proteins)-like proteins. SSB proteins contain a central SPRY domain and a C-terminal SOCS. SSB2 has been shown to bind to MET, the receptor protein-tyrosine kinase for ...
- cd12906
Location:46 → 217
- SPRY_SOCS1-2-4; SPRY domain in the suppressor of cytokine signaling 1, 2, 4 families (SOCS1, SOCS2, SOCS4)
The following sections contain reference sequences that belong to a
specific genome build. Explain
This section includes genomic Reference
Sequences (RefSeqs) from all assemblies on which this gene is annotated, such as
RefSeqs for chromosomes and scaffolds (contigs) from both reference and alternate
assemblies. Model RNAs and proteins are also reported here.
Reference GRCm39 C57BL/6J
Genomic
-
NC_000072.7 Reference GRCm39 C57BL/6J
- Range
-
124785640..124787582
- Download
- GenBank, FASTA, Sequence Viewer (Graphics)
mRNA and Protein(s)
-
XM_036165855.1 → XP_036021748.1 SPRY domain-containing SOCS box protein 2 isoform X1
- UniProtKB/TrEMBL
-
D3Z7N7
- Conserved Domains (1) summary
-
- cd12906
Location:46 → 201
- SPRY_SOCS1-2-4; SPRY domain in the suppressor of cytokine signaling 1, 2, 4 families (SOCS1, SOCS2, SOCS4)