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    C2orf66 chromosome 2 open reading frame 66 [ Homo sapiens (human) ]

    Gene ID: 401027, updated on 10-Dec-2024

    Summary

    Official Symbol
    C2orf66provided by HGNC
    Official Full Name
    chromosome 2 open reading frame 66provided by HGNC
    Primary source
    HGNC:HGNC:33809
    See related
    Ensembl:ENSG00000187944 AllianceGenome:HGNC:33809
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Homo sapiens
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
    Also known as
    UNQ6411; IIDS6411
    Summary
    Predicted to be located in extracellular region. [provided by Alliance of Genome Resources, Dec 2024]
    Expression
    Low expression observed in reference dataset See more
    Orthologs
    NEW
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    Genomic context

    See C2orf66 in Genome Data Viewer
    Location:
    2q33.1
    Exon count:
    4
    Annotation release Status Assembly Chr Location
    RS_2024_08 current GRCh38.p14 (GCF_000001405.40) 2 NC_000002.12 (196804417..196832139, complement)
    RS_2024_08 current T2T-CHM13v2.0 (GCF_009914755.1) 2 NC_060926.1 (197288090..197315820, complement)
    RS_2024_09 previous assembly GRCh37.p13 (GCF_000001405.25) 2 NC_000002.11 (197669141..197674079, complement)

    Chromosome 2 - NC_000002.12Genomic Context describing neighboring genes Neighboring gene coiled-coil domain containing 150 Neighboring gene uncharacterized LOC100130452 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 16912 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 16913 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 16914 Neighboring gene general transcription factor IIIC subunit 3 Neighboring gene post-GPI attachment to proteins inositol deacylase 1 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 16915 Neighboring gene ATAC-STARR-seq lymphoblastoid silent region 12206 Neighboring gene ATAC-STARR-seq lymphoblastoid silent region 12207 Neighboring gene ankyrin repeat domain 44 Neighboring gene heterogeneous nuclear ribonucleoprotein A3 pseudogene 15

    Genomic regions, transcripts, and products

    Expression

    • Project title: Tissue-specific circular RNA induction during human fetal development
    • Description: 35 human fetal samples from 6 tissues (3 - 7 replicates per tissue) collected between 10 and 20 weeks gestational time were sequenced using Illumina TruSeq Stranded Total RNA
    • BioProject: PRJNA270632
    • Publication: PMID 26076956
    • Analysis date: Mon Apr 2 22:54:59 2018

    Interactions

    Products Interactant Other Gene Complex Source Pubs Description

    General protein information

    Preferred Names
    uncharacterized protein C2orf66

    NCBI Reference Sequences (RefSeq)

    NEW Try the new Transcript table

    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_213608.3NP_998773.2  uncharacterized protein C2orf66 precursor

      Status: VALIDATED

      Source sequence(s)
      AC012486, AW768745, AY358249
      Consensus CDS
      CCDS2317.2
      UniProtKB/Swiss-Prot
      B2RNW3, Q6UXQ4
      UniProtKB/TrEMBL
      A0A5K1VW65
      Related
      ENSP00000339384.3, ENST00000342506.4
      Conserved Domains (1) summary
      pfam15846
      Location:1798
      DUF4720; Domain of unknown function (DUF4720)

    RefSeqs of Annotated Genomes: GCF_000001405.40-RS_2024_08

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCh38.p14 Primary Assembly

    Genomic

    1. NC_000002.12 Reference GRCh38.p14 Primary Assembly

      Range
      196804417..196832139 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_047444338.1XP_047300294.1  uncharacterized protein C2orf66 isoform X2

      UniProtKB/Swiss-Prot
      B2RNW3, Q6UXQ4
      UniProtKB/TrEMBL
      A0A5K1VW65
    2. XM_047444337.1XP_047300293.1  uncharacterized protein C2orf66 isoform X1

    Alternate T2T-CHM13v2.0

    Genomic

    1. NC_060926.1 Alternate T2T-CHM13v2.0

      Range
      197288090..197315820 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_054342041.1XP_054198016.1  uncharacterized protein C2orf66 isoform X2

      UniProtKB/Swiss-Prot
      B2RNW3, Q6UXQ4
      UniProtKB/TrEMBL
      A0A5K1VW65
    2. XM_054342040.1XP_054198015.1  uncharacterized protein C2orf66 isoform X1