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    PTR2 peptide transporter 2 [ Arabidopsis thaliana (thale cress) ]

    Gene ID: 814735, updated on 18-Sep-2024

    Summary

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    Official Symbol
    PTR2
    Official Full Name
    peptide transporter 2
    Primary source
    TAIR:AT2G02040
    Locus tag
    AT2G02040
    See related
    Araport:AT2G02040
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Arabidopsis thaliana (ecotype: Columbia)
    Lineage
    Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta; Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis
    Also known as
    ARABIDOPSIS THALIANA PEPTIDE TRANSPORTER 2; AtNPF8.3; ATPTR2; ATPTR2-B; F14H20.11; F14H20_11; HISTIDINE TRANSPORT PROTEIN; NITRATE TRANSPORTER 1; NPF8.3; NRT1/ PTR family 8.3; NTR1; peptide transporter 2; PTR2-B
    Summary
    Encodes a di- and tri-peptide transporter that recognizes a variety of different amino acid combinations. Expression of the transcripts for this gene can be detected in the embryo through in situ hybridization. This protein does not have nitrate transporter activity based on oocyte transport assays.
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    Genomic context

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    See PTR2 in Genome Data Viewer
    Location:
    chromosome: 2
    Exon count:
    4
    Sequence:
    Chromosome: 2; NC_003071.7 (487398..489941)

    Chromosome 2 - NC_003071.7Genomic Context describing neighboring genes Neighboring gene F-box family protein Neighboring gene ncRNA Neighboring gene NADH-ubiquinone oxidoreductase B18 subunit Neighboring gene Homeodomain-like superfamily protein

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_003071.7

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Peptide transporter2 (PTR2) enhances water uptake during early seed germination in Arabidopsis thaliana. Choi MG, et al. Plant Mol Biol, 2020 Apr. PMID 31997111, Free PMC Article
    2. Cloning of a second Arabidopsis peptide transport gene. Song W, et al. Plant Physiol, 1996 Jan. PMID 8587981, Free PMC Article
    3. Antisense expression of the peptide transport gene AtPTR2-B delays flowering and arrests seed development in transgenic Arabidopsis plants. Song W, et al. Plant Physiol, 1997 Jul. PMID 9232875, Free PMC Article
    4. Spliceosome disassembly factors ILP1 and NTR1 promote miRNA biogenesis in Arabidopsis thaliana. Wang J, et al. Nucleic Acids Res, 2019 Sep 5. PMID 31216029, Free PMC Article
    5. NTR1 encodes a high affinity oligopeptide transporter in Arabidopsis. Rentsch D, et al. FEBS Lett, 1995 Aug 21. PMID 7656990

    See all (17) citations in PubMed

    GeneRIFs: Gene References Into Functions

    What's a GeneRIF?
    1. PTR2 in Arabidopsis thaliana is negatively regulated by ABI4 and plays a key role in water uptake by seeds, ensuring that imbibed seeds proceed to germination.
      Title: Peptide transporter2 (PTR2) enhances water uptake during early seed germination in Arabidopsis thaliana.
    2. Spliceosome disassembly factors ILP1 and NTR1 promote miRNA biogenesis in Arabidopsis thaliana.
      Title: Spliceosome disassembly factors ILP1 and NTR1 promote miRNA biogenesis in Arabidopsis thaliana.
    Submit: New GeneRIF Correction

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Homology

    NM_126265.4

    Gene Ontology Provided by TAIR

    Function Evidence Code Pubs
    enables dipeptide transmembrane transporter activity IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    enables dipeptide transmembrane transporter activity IGI
    Inferred from Genetic Interaction
    more info
    		 PubMed 
    enables high-affinity oligopeptide transmembrane transporter activity IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    NOT enables nitrate transmembrane transporter activity IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    enables peptide transmembrane transporter activity ISS
    Inferred from Sequence or Structural Similarity
    more info
    		 PubMed 
    enables tripeptide transmembrane transporter activity IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    Process Evidence Code Pubs
    acts_upstream_of_or_within dipeptide transport IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    acts_upstream_of_or_within peptide transport TAS
    Traceable Author Statement
    more info
    		 PubMed 
    acts_upstream_of_or_within tripeptide transport IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in Golgi apparatus HDA PubMed 
    located_in plant-type vacuole HDA PubMed 
    located_in plant-type vacuole membrane IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    located_in vacuolar membrane HDA PubMed 
    located_in vacuole HDA PubMed 

    General protein information

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    Preferred Names
    peptide transporter 2
    NP_178313.1
    • peptide transporter 2 (PTR2); FUNCTIONS IN: dipeptide transporter activity, high affinity oligopeptide transporter activity, tripeptide transporter activity, peptide transporter activity, transporter activity; INVOLVED IN: dipeptide transport, tripeptide transport, peptide transport; LOCATED IN: vacuolar membrane, plasma membrane, vacuole, plant-type vacuole; EXPRESSED IN: 24 plant structures; EXPRESSED DURING: 13 growth stages; CONTAINS InterPro DOMAIN/s: PTR2 family proton/oligopeptide symporter, conserved site (InterPro:IPR018456), Oligopeptide transporter (InterPro:IPR000109), Major facilitator superfamily, general substrate transporter (InterPro:IPR016196); BEST Arabidopsis thaliana protein match is: Major facilitator superfamily protein (TAIR:AT1G62200.1); Has 8080 Blast hits to 7668 proteins in 1494 species: Archae - 0; Bacteria - 3960; Metazoa - 799; Fungi - 488; Plants - 2224; Viruses - 0; Other Eukaryotes - 609 (source: NCBI BLink).

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003071.7 Reference assembly

      Range
      487398..489941
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_126265.4 → NP_178313.1  peptide transporter 2 [Arabidopsis thaliana]

      See identical proteins and their annotated locations for NP_178313.1

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      P46032
      UniProtKB/TrEMBL
      A0A178VV15, A0A5S9WWG6
      Conserved Domains (1) summary
      cd17418
      Location:45 → 579
      MFS_NPF8; NRT1/PTR family (NPF), subfamily 8 of the Major Facilitator Superfamily of transporters
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    P46032.1

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