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    TOM20-2 translocase outer membrane 20-2 [ Arabidopsis thaliana (thale cress) ]

    Gene ID: 839629, updated on 18-Sep-2024

    Summary

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    Official Symbol
    TOM20-2
    Official Full Name
    translocase outer membrane 20-2
    Primary source
    TAIR:AT1G27390
    Locus tag
    AT1G27390
    See related
    Araport:AT1G27390
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Arabidopsis thaliana (ecotype: Columbia)
    Lineage
    Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta; Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis
    Also known as
    F17L21.18; F17L21_18; translocase outer membrane 20-2
    Summary
    Form of TOM20, which is a component of the TOM complex, involved in transport of nuclear-encoded mitochondrial proteins
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    Genomic context

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    See TOM20-2 in Genome Data Viewer
    Location:
    chromosome: 1
    Exon count:
    6
    Sequence:
    Chromosome: 1; NC_003070.9 (9513081..9515050, complement)

    Chromosome 1 - NC_003070.9Genomic Context describing neighboring genes Neighboring gene ROP-interactive CRIB motif-containing protein 2 Neighboring gene phosphoribosylformylglycinamidine synthase Neighboring gene Ribosomal protein L22p/L17e family protein Neighboring gene ncRNA Neighboring gene DNA repair metallo-beta-lactamase family protein

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_003070.9

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Purification and characterization of the preprotein translocase of the outer mitochondrial membrane from Arabidopsis. Identification of multiple forms of TOM20. Werhahn W, et al. Plant Physiol, 2001 Feb. PMID 11161051, Free PMC Article
    2. Arabidopsis DGD1 SUPPRESSOR1 Is a Subunit of the Mitochondrial Contact Site and Cristae Organizing System and Affects Mitochondrial Biogenesis. Li L, et al. Plant Cell, 2019 Aug. PMID 31118221, Free PMC Article
    3. Functional definition of outer membrane proteins involved in preprotein import into mitochondria. Lister R, et al. Plant Cell, 2007 Nov. PMID 17981999, Free PMC Article
    4. Proteomic identification of divalent metal cation binding proteins in plant mitochondria. Herald VL, et al. FEBS Lett, 2003 Feb 27. PMID 12606038
    5. A transcriptomic and proteomic characterization of the Arabidopsis mitochondrial protein import apparatus and its response to mitochondrial dysfunction. Lister R, et al. Plant Physiol, 2004 Feb. PMID 14730085, Free PMC Article

    See all (12) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Homology

    NM_001332759.1
    NM_102502.3

    Gene Ontology Provided by TAIR

    Function Evidence Code Pubs
    enables metal ion binding IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    enables protein-transporting ATPase activity TAS
    Traceable Author Statement
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in protein insertion into mitochondrial outer membrane IEA
    Inferred from Electronic Annotation
    more info
    		  
    acts_upstream_of_or_within protein targeting to mitochondrion IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    acts_upstream_of_or_within protein targeting to mitochondrion TAS
    Traceable Author Statement
    more info
    		 PubMed 
    Component Evidence Code Pubs
    part_of TIM23 mitochondrial import inner membrane translocase complex TAS
    Traceable Author Statement
    more info
    		 PubMed 
    NOT located_in cytosol RCA
    inferred from Reviewed Computational Analysis
    more info
    		 PubMed 
    located_in cytosolic ribosome HDA PubMed 
    located_in mitochondrial inner membrane HDA PubMed 
    located_in mitochondrial outer membrane HDA PubMed 
    located_in mitochondrial outer membrane IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    part_of mitochondrial outer membrane translocase complex IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    part_of mitochondrial outer membrane translocase complex IEA
    Inferred from Electronic Annotation
    more info
    		  
    located_in mitochondrion HDA PubMed 
    located_in mitochondrion IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    located_in mitochondrion ISM
    Inferred from Sequence Model
    more info
    		  
    located_in nucleus HDA PubMed 

    General protein information

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    Preferred Names
    translocase outer membrane 20-2
    NP_174059.2
    • translocase outer membrane 20-2 (TOM20-2); FUNCTIONS IN: P-P-bond-hydrolysis-driven protein transmembrane transporter activity, metal ion binding; INVOLVED IN: protein targeting to mitochondrion; LOCATED IN: in 6 components; EXPRESSED IN: 23 plant structures; EXPRESSED DURING: 13 growth stages; CONTAINS InterPro DOMAIN/s: Plant specific mitochondrial import receptor subunit TOM20 (InterPro:IPR010547); BEST Arabidopsis thaliana protein match is: translocase of outer membrane 20 kDa subunit 3 (TAIR:AT3G27080.1); Has 98 Blast hits to 94 proteins in 24 species: Archae - 0; Bacteria - 6; Metazoa - 1; Fungi - 0; Plants - 91; Viruses - 0; Other Eukaryotes - 0 (source: NCBI BLink).

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003070.9 Reference assembly

      Range
      9513081..9515050 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_102502.3 → NP_174059.2  translocase outer membrane 20-2 [Arabidopsis thaliana]

      See identical proteins and their annotated locations for NP_174059.2

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      P82873, Q2HIH9, Q9FZJ6
      UniProtKB/TrEMBL
      A0A178W7F2, A0A5S9W431, A0A654EF10
      Conserved Domains (2) summary
      sd00006
      Location:31 → 71
      TPR; TPR repeat [structural motif]
      pfam06552
      Location:8 → 201
      TOM20_plant; Plant specific mitochondrial import receptor subunit TOM20

    2. NM_001332759.1 → NP_001322710.1  translocase outer membrane 20-2 [Arabidopsis thaliana]

      Status: REVIEWED

      UniProtKB/TrEMBL
      A0A1P8AUU7
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    P82873.2

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