RGF3 root meristem growth factor [Arabidopsis thaliana (thale cress)] - Gene

Summary

Official Symbol: RGF3
Official Full Name: root meristem growth factor
Primary source: TAIR:AT2G04025
Locus tag: AT2G04025
See related: Araport:AT2G04025
Gene type: protein coding
RefSeq status: REVIEWED
Organism: Arabidopsis thaliana (ecotype: Columbia)
Lineage: Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta; Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis
Also known as: F3C11.1; F3C11_1; GLV7; GOLVEN 7; root meristem growth factor 3
Summary: Encodes a root meristem growth factor (RGF). Belongs to a family of functionally redundant homologous peptides that are secreted, tyrosine-sulfated, and expressed mainly in the stem cell area and the innermost layer of central columella cells. RGFs are required for maintenance of the root stem cell niche and transit amplifying cell proliferation. Members of this family include: At5g60810 (RGF1), At1g13620 (RGF2), At2g04025 (RGF3), At3g30350 (RGF4), At5g51451 (RGF5), At4g16515 (RGF6), At3g02240 (RGF7), At2g03830 (RGF8) and At5g64770 (RGF9).
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Chromosome 2 - NC_003071.7 Genomic Context describing neighboring genes

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Function	Evidence Code	Pubs
enables growth factor activity	IDA Inferred from Direct Assay more info	PubMed
enables protein binding	IPI Inferred from Physical Interaction more info	PubMed

Process	Evidence Code	Pubs
involved_in cell differentiation	IDA Inferred from Direct Assay more info	PubMed
involved_in positive regulation of cell population proliferation	IDA Inferred from Direct Assay more info	PubMed
acts_upstream_of_or_within positive regulation of gene expression	IEP Inferred from Expression Pattern more info	PubMed
involved_in regulation of asymmetric cell division	ISS Inferred from Sequence or Structural Similarity more info
involved_in regulation of lateral root development	ISS Inferred from Sequence or Structural Similarity more info
acts_upstream_of_or_within regulation of root meristem growth	IGI Inferred from Genetic Interaction more info	PubMed
involved_in regulation of root meristem growth	ISS Inferred from Sequence or Structural Similarity more info
involved_in regulation of root morphogenesis	ISS Inferred from Sequence or Structural Similarity more info

Component	Evidence Code	Pubs
located_in extracellular region	ISM Inferred from Sequence Model more info
located_in extracellular space	ISS Inferred from Sequence or Structural Similarity more info	PubMed
located_in nucleus	ISM Inferred from Sequence Model more info

NP_178486.2

root meristem growth factor 3 (RGF3); FUNCTIONS IN: molecular_function unknown; INVOLVED IN: regulation of root meristem growth, positive regulation of gene expression; LOCATED IN: endomembrane system; EXPRESSED IN: stem, root, carpel; EXPRESSED DURING: 4 anthesis; BEST Arabidopsis thaliana protein match is: unknown protein (TAIR:AT1G13620.1); Has 35333 Blast hits to 34131 proteins in 2444 species: Archae - 798; Bacteria - 22429; Metazoa - 974; Fungi - 991; Plants - 531; Viruses - 0; Other Eukaryotes - 9610 (source: NCBI BLink).